MT-ND6 Gene

HGNC Family	Mitochondrial respiratory chain complexes
Name	NADH dehydrogenase, subunit 6 (complex I)
Synonyms	ND6, MTND6
Proteins	NU6M_HUMAN
NCBI Gene ID	4541
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Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

MT-ND6 has 901 functional associations with biological entities spanning 7 categories (organism, functional term, phrase or reference, chemical, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 26 datasets.

Click the + buttons to view associations for MT-ND6 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

MT-ND6 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	CORUM Protein Complexes	protein complexs containing MT-ND6 protein from the CORUM Protein Complexes dataset.
	CTD Gene-Chemical Interactions	chemicals interacting with MT-ND6 gene/protein from the curated CTD Gene-Chemical Interactions dataset.
	CTD Gene-Disease Associations	diseases associated with MT-ND6 gene/protein from the curated CTD Gene-Disease Associations dataset.
	DisGeNET Gene-Disease Associations	diseases associated with MT-ND6 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with MT-ND6 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing MT-ND6 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
	GAD Gene-Disease Associations	diseases associated with MT-ND6 gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
	GeneRIF Biological Term Annotations	biological terms co-occuring with MT-ND6 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
	GEO Signatures of Differentially Expressed Genes for Diseases	disease perturbations changing expression of MT-ND6 gene from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.
	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	gene perturbations changing expression of MT-ND6 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
	GEO Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of MT-ND6 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset.
	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	transcription factor perturbations changing expression of MT-ND6 gene from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.
	GEO Signatures of Differentially Expressed Genes for Viral Infections	virus perturbations changing expression of MT-ND6 gene from the GEO Signatures of Differentially Expressed Genes for Viral Infections dataset.
	GO Biological Process Annotations 2015	biological processes involving MT-ND6 gene from the curated GO Biological Process Annotations 2015 dataset.
	GO Cellular Component Annotations 2015	cellular components containing MT-ND6 protein from the curated GO Cellular Component Annotations 2015 dataset.
	GO Molecular Function Annotations 2015	molecular functions performed by MT-ND6 gene from the curated GO Molecular Function Annotations 2015 dataset.
	HPO Gene-Disease Associations	phenotypes associated with MT-ND6 gene by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.
	HuGE Navigator Gene-Phenotype Associations	phenotypes associated with MT-ND6 gene by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.
	InterPro Predicted Protein Domain Annotations	protein domains predicted for MT-ND6 protein from the InterPro Predicted Protein Domain Annotations dataset.
	KEGG Pathways	pathways involving MT-ND6 protein from the KEGG Pathways dataset.
	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	cell lines with high or low expression of MT-ND6 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles dataset.
	MGI Mouse Phenotype Associations 2023	phenotypes of transgenic mice caused by MT-ND6 gene mutations from the MGI Mouse Phenotype Associations 2023 dataset.
	MiRTarBase microRNA Targets	microRNAs targeting MT-ND6 gene in low- or high-throughput microRNA targeting studies from the MiRTarBase microRNA Targets dataset.
	MPO Gene-Phenotype Associations	phenotypes of transgenic mice caused by MT-ND6 gene mutations from the MPO Gene-Phenotype Associations dataset.
	PFOCR Pathway Figure Associations 2023	pathways involving MT-ND6 protein from the PFOCR Pathway Figure Associations 2023 dataset.
	WikiPathways Pathways 2014	pathways involving MT-ND6 protein from the Wikipathways Pathways 2014 dataset.