MTRNR2L3 Gene

Name	MT-RNR2-like 3
Description	Predicted to enable receptor antagonist activity. Predicted to be involved in negative regulation of execution phase of apoptosis. Predicted to be located in cytoplasm and extracellular region. [provided by Alliance of Genome Resources, Mar 2025]
Synonyms	HN3
Proteins	HMN3_HUMAN
NCBI Gene ID	100462983
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Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

MTRNR2L3 has 436 functional associations with biological entities spanning 5 categories (molecular profile, functional term, phrase or reference, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 19 datasets.

Click the + buttons to view associations for MTRNR2L3 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

MTRNR2L3 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of MTRNR2L3 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of MTRNR2L3 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of MTRNR2L3 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of MTRNR2L3 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at MTRNR2L3 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of MTRNR2L3 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of MTRNR2L3 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	GeneRIF Biological Term Annotations	biological terms co-occuring with MTRNR2L3 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
	GO Biological Process Annotations 2023	biological processes involving MTRNR2L3 gene from the curated GO Biological Process Annotations 2023 dataset.
	GO Cellular Component Annotations 2015	cellular components containing MTRNR2L3 protein from the curated GO Cellular Component Annotations 2015 dataset.
	GO Molecular Function Annotations 2023	molecular functions performed by MTRNR2L3 gene from the curated GO Molecular Function Annotations 2023 dataset.
	GTEx Tissue Gene Expression Profiles	tissues with high or low expression of MTRNR2L3 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset.
	InterPro Predicted Protein Domain Annotations	protein domains predicted for MTRNR2L3 protein from the InterPro Predicted Protein Domain Annotations dataset.
	JASPAR Predicted Transcription Factor Targets	transcription factors regulating expression of MTRNR2L3 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.
	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	cell lines with high or low copy number of MTRNR2L3 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.
	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	transcription factor perturbations changing expression of MTRNR2L3 gene from the KnockTF Gene Expression Profiles with Transcription Factor Perturbations dataset.
	Roadmap Epigenomics Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at MTRNR2L3 gene from the Roadmap Epigenomics Histone Modification Site Profiles dataset.
	TargetScan Predicted Conserved microRNA Targets	microRNAs regulating expression of MTRNR2L3 gene predicted using conserved miRNA seed sequences from the TargetScan Predicted Conserved microRNA Targets dataset.
	TargetScan Predicted Nonconserved microRNA Targets	microRNAs regulating expression of MTRNR2L3 gene predicted using nonconserved miRNA seed sequences from the TargetScan Predicted Nonconserved microRNA Targets dataset.