NCAM1 Gene

HGNC Family	Fibronectin type III domain containing, CD molecules (CD), Immunoglobulin superfamily domain containing
Name	neural cell adhesion molecule 1
Description	This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein plays a role in the development of the nervous system by regulating neurogenesis, neurite outgrowth, and cell migration. This protein is also involved in the expansion of T lymphocytes, B lymphocytes and natural killer (NK) cells which play an important role in immune surveillance. This protein plays a role in signal transduction by interacting with fibroblast growth factor receptors, N-cadherin and other components of the extracellular matrix and by triggering signalling cascades involving FYN-focal adhesion kinase (FAK), mitogen-activated protein kinase (MAPK), and phosphatidylinositol 3-kinase (PI3K). One prominent isoform of this gene, cell surface molecule CD56, plays a role in several myeloproliferative disorders such as acute myeloid leukemia and differential expression of this gene is associated with differential disease progression. For example, increased expression of CD56 is correlated with lower survival in acute myeloid leukemia patients whereas increased severity of COVID-19 is correlated with decreased abundance of CD56-expressing NK cells in peripheral blood. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. [provided by RefSeq, Aug 2020]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nNCAM1, also known as CD56, is a multifunctional transmembrane glycoprotein with pivotal roles in the nervous system. It regulates synaptic plasticity, neurodevelopment, and neurogenesis, and its processing—including proteolytic cleavage and post‐translational modifications such as polysialylation and ubiquitylation—affects ligand binding and receptor recycling. For example, a cleaved NCAM variant has been linked to schizophrenia (1:"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": ", while overexpression of NCAM in ischemic cardiomyopathy suggests a role in cardiac remodeling (2:."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "2"}]}, {"type": "t", "text": " Genetic and functional studies further nominate NCAM1 as a candidate in psychiatric disorders such as bipolar disorder and schizophrenia, underscoring its importance in neural plasticity and signal transduction (3:"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "3"}]}, {"type": "t", "text": "; 7:."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "4"}]}, {"type": "t", "text": " In addition, regulated endocytosis and intracellular recycling of NCAM in neurons has been demonstrated to be critical for proper neuronal function (8:"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "5"}]}, {"type": "t", "text": "; 9:"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "6"}]}, {"type": "t", "text": ", and polysialylation of NCAM modulates its binding to dopamine and growth factors such as BDNF, a mechanism that may contribute to the pathogenesis of various psychiatric conditions (12:"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "7"}]}, {"type": "t", "text": "; 14:"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "8"}]}, {"type": "t", "text": "; 15:."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "9"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nIn oncology and immune-related disorders, NCAM1 serves both as a biological mediator and as a useful diagnostic marker. Interactions of NCAM1 with fibroblast growth factor receptor 1 (FGFR1) have been implicated in promoting cell migration and tumor progression in various cancers, including epithelial ovarian carcinoma and Wilms’ tumor, where NCAM1 marks progenitor cell fractions (5:"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "10"}]}, {"type": "t", "text": "; 11:"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "11"}]}, {"type": "t", "text": "; 13:."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "12"}]}, {"type": "t", "text": " Moreover, NCAM1 expression in tumor‐associated macrophages positively regulates migration and survival through PI3K–Akt and FGFR1 signaling in the esophageal cancer microenvironment (16:"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "13"}]}, {"type": "t", "text": "; 17:."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "14"}]}, {"type": "t", "text": " As a neuroendocrine marker, NCAM1 is used diagnostically to identify neuroendocrine differentiation in thoracic tumors (18:"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "15"}]}, {"type": "t", "text": ", and aberrant NCAM1 presentation can also lead to autoimmune responses, as observed in membranous lupus nephritis (20:."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "16"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nGenetic association studies have implicated NCAM1 in substance dependence and other complex traits. Although evidence for a direct role in nicotine dependence is modest (6:"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "17"}]}, {"type": "t", "text": ", significant haplotype associations with alcohol dependence have been reported (10:."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "18"}]}, {"type": "t", "text": " In addition, large-scale genome‐wide analyses of irritable bowel syndrome have identified NCAM1 among a group of susceptibility loci that also relate to mood and anxiety disorders (21:."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "19"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nBeyond its classical role in neural cells, NCAM1 functions as a key molecule in the innate immune system. In natural killer (NK) cells, which characteristically express CD56, NCAM1 has been shown to participate in pathogen sensing; recent studies indicate that it acts as a pathogen recognition receptor mediating NK cell activation in response to fungal challenges, such as Aspergillus fumigatus (19:."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "20"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "M P Vawter, N Usen, L Thatcher, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Characterization of human cleaved N-CAM and association with schizophrenia."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Exp Neurol (2001)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1006/exnr.2001.7790"}], "href": "https://doi.org/10.1006/exnr.2001.7790"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "11681838"}], "href": "https://pubmed.ncbi.nlm.nih.gov/11681838"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Stefan Gattenlöhner, Christiane Waller, Georg Ertl, et al. "}, {"type": "b", "children": [{"type": "t", "text": "NCAM(CD56) and RUNX1(AML1) are up-regulated in human ischemic cardiomyopathy and a rat model of chronic cardiac ischemia."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Am J Pathol (2003)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/S0002-9440(10)63467-0"}], "href": "https://doi.org/10.1016/S0002-9440(10"}, {"type": "t", "text": "63467-0) PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12937148"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12937148"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Daisuke Nakata, Frederic A Troy "}, {"type": "b", "children": [{"type": "t", "text": "Degree of polymerization (DP) of polysialic acid (polySia) on neural cell adhesion molecules (N-CAMS): development and application of a new strategy to accurately determine the DP of polySia chains on N-CAMS."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2005)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M508762200"}], "href": "https://doi.org/10.1074/jbc.M508762200"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16172115"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16172115"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Mary E Atz, Brandi Rollins, Marquis P Vawter "}, {"type": "b", "children": [{"type": "t", "text": "NCAM1 association study of bipolar disorder and schizophrenia: polymorphisms and alternatively spliced isoforms lead to similarities and differences."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Psychiatr Genet (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1097/YPG.0b013e328012d850"}], "href": "https://doi.org/10.1097/YPG.0b013e328012d850"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17413444"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17413444"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "I Jakovcevski, Z Mo, N Zecevic "}, {"type": "b", "children": [{"type": "t", "text": "Down-regulation of the axonal polysialic acid-neural cell adhesion molecule expression coincides with the onset of myelination in the human fetal forebrain."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Neuroscience (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.neuroscience.2007.07.044"}], "href": "https://doi.org/10.1016/j.neuroscience.2007.07.044"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17900814"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17900814"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Simone Diestel, Daniel Schaefer, Harold Cremer, et al. "}, {"type": "b", "children": [{"type": "t", "text": "NCAM is ubiquitylated, endocytosed and recycled in neurons."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cell Sci (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1242/jcs.019729"}], "href": "https://doi.org/10.1242/jcs.019729"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17971410"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17971410"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Ryo Isomura, Ken Kitajima, Chihiro Sato "}, {"type": "b", "children": [{"type": "t", "text": "Structural and functional impairments of polysialic acid by a mutated polysialyltransferase found in schizophrenia."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M111.221143"}], "href": "https://doi.org/10.1074/jbc.M111.221143"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21464126"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21464126"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Emilio Varea, Ramón Guirado, Javier Gilabert-Juan, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Expression of PSA-NCAM and synaptic proteins in the amygdala of psychiatric disorder patients."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Psychiatr Res (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.jpsychires.2011.10.011"}], "href": "https://doi.org/10.1016/j.jpsychires.2011.10.011"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22099865"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22099865"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Javier Gilabert-Juan, Emilio Varea, Ramón Guirado, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Alterations in the expression of PSA-NCAM and synaptic proteins in the dorsolateral prefrontal cortex of psychiatric disorder patients."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Neurosci Lett (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.neulet.2012.09.032"}], "href": "https://doi.org/10.1016/j.neulet.2012.09.032"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23022470"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23022470"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Elena Sanchez-Heras, Fiona V Howell, Gareth Williams, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The fibroblast growth factor receptor acid box is essential for interactions with N-cadherin and all of the major isoforms of neural cell adhesion molecule."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M608655200"}], "href": "https://doi.org/10.1074/jbc.M608655200"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17005551"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17005551"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Naomi Pode-Shakked, Sally Metsuyanim, Eithan Rom-Gross, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Developmental tumourigenesis: NCAM as a putative marker for the malignant renal stem/progenitor cell population."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cell Mol Med (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1111/j.1582-4934.2008.00607.x"}], "href": "https://doi.org/10.1111/j.1582-4934.2008.00607.x"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20187302"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20187302"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Silvia Zecchini, Lorenzo Bombardelli, Alessandra Decio, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The adhesion molecule NCAM promotes ovarian cancer progression via FGFR signalling."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "EMBO Mol Med (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/emmm.201100152"}], "href": "https://doi.org/10.1002/emmm.201100152"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21739604"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21739604"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Nobuhisa Takase, Yu-Ichiro Koma, Naoki Urakawa, et al. "}, {"type": "b", "children": [{"type": "t", "text": "NCAM- and FGF-2-mediated FGFR1 signaling in the tumor microenvironment of esophageal cancer regulates the survival and migration of tumor-associated macrophages and cancer cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Lett (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.canlet.2016.06.009"}], "href": "https://doi.org/10.1016/j.canlet.2016.06.009"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27317650"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27317650"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Emily M Mace, Justin T Gunesch, Amera Dixon, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Human NK cell development requires CD56-mediated motility and formation of the developmental synapse."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Commun (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/ncomms12171"}], "href": "https://doi.org/10.1038/ncomms12171"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27435370"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27435370"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Lisa M Rooper, Rajni Sharma, Qing Kay Li, et al. "}, {"type": "b", "children": [{"type": "t", "text": "INSM1 Demonstrates Superior Performance to the Individual and Combined Use of Synaptophysin, Chromogranin and CD56 for Diagnosing Neuroendocrine Tumors of the Thoracic Cavity."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Am J Surg Pathol (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1097/PAS.0000000000000916"}], "href": "https://doi.org/10.1097/PAS.0000000000000916"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28719469"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28719469"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Tiffany N Caza, Samar I Hassen, Michael Kuperman, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Neural cell adhesion molecule 1 is a novel autoantigen in membranous lupus nephritis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Kidney Int (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.kint.2020.09.016"}], "href": "https://doi.org/10.1016/j.kint.2020.09.016"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33045259"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33045259"}]}, {"type": "r", "ref": 17, "children": [{"type": "t", "text": "Joel Gelernter, Yi Yu, Roger Weiss, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Haplotype spanning TTC12 and ANKK1, flanked by the DRD2 and NCAM1 loci, is strongly associated to nicotine dependence in two distinct American populations."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Hum Mol Genet (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1093/hmg/ddl426"}], "href": "https://doi.org/10.1093/hmg/ddl426"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17085484"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17085484"}]}, {"type": "r", "ref": 18, "children": [{"type": "t", "text": "Bao-Zhu Yang, Henry R Kranzler, Hongyu Zhao, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Haplotypic variants in DRD2, ANKK1, TTC12, and NCAM1 are associated with comorbid alcohol and drug dependence."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Alcohol Clin Exp Res (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1111/j.1530-0277.2008.00800.x"}], "href": "https://doi.org/10.1111/j.1530-0277.2008.00800.x"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18828801"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18828801"}]}, {"type": "r", "ref": 19, "children": [{"type": "t", "text": "Chris Eijsbouts, Tenghao Zheng, Nicholas A Kennedy, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Genet (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41588-021-00950-8"}], "href": "https://doi.org/10.1038/s41588-021-00950-8"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34741163"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34741163"}]}, {"type": "r", "ref": 20, "children": [{"type": "t", "text": "Sabrina Ziegler, Esther Weiss, Anna-Lena Schmitt, et al. "}, {"type": "b", "children": [{"type": "t", "text": "CD56 Is a Pathogen Recognition Receptor on Human Natural Killer Cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Sci Rep (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41598-017-06238-4"}], "href": "https://doi.org/10.1038/s41598-017-06238-4"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28733594"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28733594"}]}]}]}
Synonyms	MSK39, NCAM, CD56
Proteins	NCAM1_HUMAN
NCBI Gene ID	4684
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

NCAM1 has 15,765 functional associations with biological entities spanning 9 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 125 datasets.

Click the + buttons to view associations for NCAM1 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

NCAM1 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of NCAM1 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of NCAM1 gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of NCAM1 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of NCAM1 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of NCAM1 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of NCAM1 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of NCAM1 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of NCAM1 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of NCAM1 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of NCAM1 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CCLE Cell Line Gene Mutation Profiles	cell lines with NCAM1 gene mutations from the CCLE Cell Line Gene Mutation Profiles dataset.
	CCLE Cell Line Proteomics	Cell lines associated with NCAM1 protein from the CCLE Cell Line Proteomics dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with NCAM1 gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of NCAM1 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of NCAM1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of NCAM1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of NCAM1 gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing NCAM1 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing NCAM1 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores	cellular components containing NCAM1 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	cellular components containing NCAM1 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with NCAM1 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with NCAM1 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of NCAM1 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with NCAM1 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Chemical Interactions	chemicals interacting with NCAM1 gene/protein from the curated CTD Gene-Chemical Interactions dataset.
	CTD Gene-Disease Associations	diseases associated with NCAM1 gene/protein from the curated CTD Gene-Disease Associations dataset.
	dbGAP Gene-Trait Associations	traits associated with NCAM1 gene in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.
	DeepCoverMOA Drug Mechanisms of Action	small molecule perturbations with high or low expression of NCAM1 protein relative to other small molecule perturbations from the DeepCoverMOA Drug Mechanisms of Action dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores	diseases associated with NCAM1 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	diseases associated with NCAM1 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with NCAM1 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with NCAM1 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with NCAM1 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with NCAM1 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at NCAM1 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of NCAM1 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of NCAM1 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing NCAM1 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
	GAD Gene-Disease Associations	diseases associated with NCAM1 gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.