NDFIP1 Gene

Name	Nedd4 family interacting protein 1
Description	The protein encoded by this gene belongs to a small group of evolutionarily conserved proteins with three transmembrane domains. It is a potential target for ubiquitination by the Nedd4 family of proteins. This protein is thought to be part of a family of integral Golgi membrane proteins. [provided by RefSeq, Jul 2008]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nNDFIP1 functions as a critical adaptor protein that recruits and activates members of the Nedd4 family of HECT domain E3 ubiquitin ligases. By binding to its targets via PY motifs, NDFIP1 relieves intrinsic autoinhibition of these ligases, thereby promoting both their self‐ubiquitination and the ubiquitination of diverse substrate proteins. This activation underlies its broad regulatory impact on key signaling molecules, such as MAVS and BRAT1, and modulates receptor tyrosine kinase pathways. Collectively, these molecular events regulate protein turnover and intracellular trafficking essential for maintaining cellular homeostasis."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "6"}]}, {"type": "t", "text": ""}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nBeyond its direct role in ubiquitin ligase activation, NDFIP1 crucially governs the trafficking and degradation of several membrane and mitochondrial proteins that impact metal ion homeostasis and cellular excitability. For example, NDFIP1 mediates the ubiquitination and degradation of the metal transporter DMT1, thereby limiting iron and cobalt entry into neurons, and it facilitates degradation of ferroportin to regulate systemic iron levels. In cardiac cells, NDFIP1 recruits Nedd4-2 to the Golgi apparatus to direct the degradation of mature hERG channels, a mechanism with implications for arrhythmia disorders. Moreover, by being upregulated in response to metal complexes and neurotoxic stress, NDFIP1 exerts neuroprotective effects in Parkinson’s disease models—ameliorating mitochondrial dysfunction via regulation of channels like VDAC and reducing accumulation of toxic proteins."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "7", "end_ref": "13"}]}, {"type": "t", "text": ""}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nIn addition to its roles in protein trafficking and neuroprotection, NDFIP1 has emerged as an important regulator in tumor suppression and immune cell function. In certain cancers such as uveal melanoma and non‐small cell lung cancer, reduced NDFIP1 expression (or its targeting by oncogenic microRNAs) permits the accumulation of oncogenic factors like TAZ, thereby promoting cell proliferation and invasion. In pancreatic β-cells, alterations in NDFIP1 levels modulate cytokine-induced apoptosis and influence the unfolded protein response, affecting insulin secretion. Finally, genetic variants and differential expression of NDFIP1 are linked with altered activation, metabolic activity, and homeostatic regulation in immune cells, underscoring its role as a negative regulator that limits excessive immune responses."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "14", "end_ref": "18"}]}, {"type": "t", "text": ""}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Ulrich Putz, Jason Howitt, Jenny Lackovic, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Nedd4 family-interacting protein 1 (Ndfip1) is required for the exosomal secretion of Nedd4 family proteins."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M804120200"}], "href": "https://doi.org/10.1074/jbc.M804120200"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18819914"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18819914"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Thomas Mund, Hugh R B Pelham "}, {"type": "b", "children": [{"type": "t", "text": "Control of the activity of WW-HECT domain E3 ubiquitin ligases by NDFIP proteins."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "EMBO Rep (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/embor.2009.30"}], "href": "https://doi.org/10.1038/embor.2009.30"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19343052"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19343052"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Thomas Mund, Hugh R B Pelham "}, {"type": "b", "children": [{"type": "t", "text": "Regulation of PTEN/Akt and MAP kinase signaling pathways by the ubiquitin ligase activators Ndfip1 and Ndfip2."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Proc Natl Acad Sci U S A (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1073/pnas.0911714107"}], "href": "https://doi.org/10.1073/pnas.0911714107"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20534535"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20534535"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Yetao Wang, Xiaomei Tong, Xin Ye "}, {"type": "b", "children": [{"type": "t", "text": "Ndfip1 negatively regulates RIG-I-dependent immune signaling by enhancing E3 ligase Smurf1-mediated MAVS degradation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Immunol (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.4049/jimmunol.1201445"}], "href": "https://doi.org/10.4049/jimmunol.1201445"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23087404"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23087404"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Ley-Hian Low, Yuh-Lit Chow, Yijia Li, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Nedd4 family interacting protein 1 (Ndfip1) is required for ubiquitination and nuclear trafficking of BRCA1-associated ATM activator 1 (BRAT1) during the DNA damage response."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M114.613687"}], "href": "https://doi.org/10.1074/jbc.M114.613687"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25631046"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25631046"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Hanjie Jiang, Stefani N Thomas, Zan Chen, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Comparative analysis of the catalytic regulation of NEDD4-1 and WWP2 ubiquitin ligases."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.RA119.009211"}], "href": "https://doi.org/10.1074/jbc.RA119.009211"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31578285"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31578285"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Jason Howitt, Ulrich Putz, Jenny Lackovic, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Divalent metal transporter 1 (DMT1) regulation by Ndfip1 prevents metal toxicity in human neurons."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Proc Natl Acad Sci U S A (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1073/pnas.0904880106"}], "href": "https://doi.org/10.1073/pnas.0904880106"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19706893"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19706893"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Jason Howitt, Amanda M Gysbers, Scott Ayton, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Increased Ndfip1 in the substantia nigra of Parkinsonian brains is associated with elevated iron levels."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PLoS One (2014)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1371/journal.pone.0087119"}], "href": "https://doi.org/10.1371/journal.pone.0087119"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24475238"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24475238"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Lisa Traeger, Steffen B Wiegand, Andrew J Sauer, et al. "}, {"type": "b", "children": [{"type": "t", "text": "UBA6 and NDFIP1 regulate the degradation of ferroportin."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Haematologica (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3324/haematol.2021.278530"}], "href": "https://doi.org/10.3324/haematol.2021.278530"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34320783"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34320783"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Yudi Kang, Jun Guo, Tonghua Yang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Regulation of the human ether-a-go-go-related gene (hERG) potassium channel by Nedd4 family interacting proteins (Ndfips)."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem J (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1042/BJ20141282"}], "href": "https://doi.org/10.1042/BJ20141282"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26363003"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26363003"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Christine Schieber, Jason Howitt, Ulrich Putz, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Cellular up-regulation of Nedd4 family interacting protein 1 (Ndfip1) using low levels of bioactive cobalt complexes."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M110.203448"}], "href": "https://doi.org/10.1074/jbc.M110.203448"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21187286"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21187286"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "L F Xing, H P Guo, D T Wang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Protective effects and mechanisms of Ndfipl on SH-SY5Y cell apoptosis in an in vitro Parkinson's disease model."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Genet Mol Res (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.4238/gmr.15026963"}], "href": "https://doi.org/10.4238/gmr.15026963"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27173227"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27173227"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Xiaomin Fu, Le Qu, Huamin Xu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Ndfip1 protected dopaminergic neurons via regulating mitochondrial function and ferroptosis in Parkinson's disease."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Exp Neurol (2024)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.expneurol.2024.114724"}], "href": "https://doi.org/10.1016/j.expneurol.2024.114724"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "38365133"}], "href": "https://pubmed.ncbi.nlm.nih.gov/38365133"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Jing Peng, Honglei Liu, Cuihong Liu "}, {"type": "b", "children": [{"type": "t", "text": "MiR-155 Promotes Uveal Melanoma Cell Proliferation and Invasion by Regulating NDFIP1 Expression."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Technol Cancer Res Treat (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1177/1533034617737923"}], "href": "https://doi.org/10.1177/1533034617737923"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29333944"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29333944"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Yirui Cheng, Xin Lu, Fan Li, et al. 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"}, {"type": "b", "children": [{"type": "t", "text": "Genetic variation in NDFIP1 modifies the metabolic patterns in immune cells of multiple sclerosis patients."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Sci Rep (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41598-021-00528-8"}], "href": "https://doi.org/10.1038/s41598-021-00528-8"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34725369"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34725369"}]}, {"type": "r", "ref": 18, "children": [{"type": "t", "text": "Ying-Le Tang, Lin Zhu, Hai-Fan Yang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Research progress on the role of "}, {"type": "a", "children": [{"type": "t", "text": "i"}], "href": "i"}, {"type": "t", "text": "Ndfip1"}, {"type": "a", "children": [{"type": "t", "text": "/i"}], "href": "/i"}, {"type": "t", "text": " (Nedd4 family interacting protein 1) in immune cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Allergol Immunopathol (Madr) (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.15586/aei.v51i1.739"}], "href": "https://doi.org/10.15586/aei.v51i1.739"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "36617825"}], "href": "https://pubmed.ncbi.nlm.nih.gov/36617825"}]}]}]}
Synonyms	N4WBP5
Proteins	NFIP1_HUMAN
NCBI Gene ID	80762
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

NDFIP1 has 7,561 functional associations with biological entities spanning 9 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 118 datasets.

Click the + buttons to view associations for NDFIP1 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

NDFIP1 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of NDFIP1 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of NDFIP1 gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of NDFIP1 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of NDFIP1 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of NDFIP1 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of NDFIP1 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of NDFIP1 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of NDFIP1 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of NDFIP1 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	small molecule perturbations changing expression of NDFIP1 gene from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of NDFIP1 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of NDFIP1 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CCLE Cell Line Proteomics	Cell lines associated with NDFIP1 protein from the CCLE Cell Line Proteomics dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with NDFIP1 gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of NDFIP1 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of NDFIP1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of NDFIP1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of NDFIP1 gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing NDFIP1 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing NDFIP1 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with NDFIP1 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with NDFIP1 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of NDFIP1 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with NDFIP1 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Disease Associations	diseases associated with NDFIP1 gene/protein from the curated CTD Gene-Disease Associations dataset.
	dbGAP Gene-Trait Associations	traits associated with NDFIP1 gene in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.
	DeepCoverMOA Drug Mechanisms of Action	small molecule perturbations with high or low expression of NDFIP1 protein relative to other small molecule perturbations from the DeepCoverMOA Drug Mechanisms of Action dataset.
	DepMap CRISPR Gene Dependency	cell lines with fitness changed by NDFIP1 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores	diseases associated with NDFIP1 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	diseases associated with NDFIP1 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with NDFIP1 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with NDFIP1 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with NDFIP1 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with NDFIP1 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at NDFIP1 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of NDFIP1 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of NDFIP1 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing NDFIP1 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
	GAD Gene-Disease Associations	diseases associated with NDFIP1 gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
	GAD High Level Gene-Disease Associations	diseases associated with NDFIP1 gene in GWAS and other genetic association datasets from the GAD High Level Gene-Disease Associations dataset.