NUDT5 Gene

HGNC Family	Nudix type motif-containing (NUDT)
Name	nudix (nucleoside diphosphate linked moiety X)-type motif 5
Description	This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates, including ADP-ribose (ADPR) and 8-oxoGua-containing 8-oxo-dADP and 8-oxo-dGDP. Protein-bound ADP ribose can be hazardous to the cell because it can modify some amino acid residues, resulting in the inhibition of ATP-activated potassium channels. 8-oxoGua is an oxidized form of guanine that can potentially alter genetic information by pairing with adenine and cytosine in RNA. Presence of 8-oxoGua in RNA results in formation of abnormal proteins due to translational errors. [provided by RefSeq, Aug 2013]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nNUDT5 plays a critical role in nuclear energy metabolism by catalyzing the hydrolysis of ADP‐ribose and related ADP sugar molecules to generate nuclear ATP. This locally produced ATP is essential for rapid chromatin remodeling, hormone‐induced transcriptional regulation, and subsequent cell proliferation. Structural studies have revealed the key catalytic residues and the coordination of multiple Mg²⁺ ions at its active site that underpin its pyrophosphatase activity."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "3"}]}, {"type": "t", "text": ""}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nIn addition to its role in nuclear ATP production, NUDT5 maintains the integrity of the nucleotide pool by sanitizing oxidized deoxyribonucleoside diphosphates. It efficiently hydrolyzes oxidized guanine nucleotides—such as 8-oxo-dGDP and 8-oxo-dADP—to their monophosphate forms, thereby preventing the misincorporation of damaged bases into DNA and RNA. Biochemical and structural analyses further reveal that NUDT5 accommodates a variety of substrates by employing distinct hydrolytic mechanisms and binding modes, which together serve as an effective defense against mutagenesis and the toxic effects of oxidative nucleotide damage."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "4", "end_ref": "10"}]}, {"type": "t", "text": ""}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nBeyond its enzymatic activities, aberrant expression of NUDT5 has emerged as a significant factor in oncogenesis. Elevated levels of NUDT5 have been linked to enhanced hormone-dependent gene regulation in breast cancer and to increased tumor proliferation, migration, and invasion in non-small-cell lung cancer, gastric carcinoma, head and neck squamous cell carcinoma, and triple-negative breast cancer. These tumor-promoting roles have been further associated with the activation of signaling pathways—including AKT, β-catenin, and Cyclin D—that drive cell cycle progression and epithelial-mesenchymal transition, thereby establishing NUDT5 as both a potent prognostic biomarker and a promising therapeutic target in cancer treatment."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "11", "end_ref": "15"}]}, {"type": "t", "text": ""}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Manwu Zha, Qing Guo, Yichun Zhang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Molecular mechanism of ADP-ribose hydrolysis by human NUDT5 from structural and kinetic studies."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Mol Biol (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.jmb.2008.04.006"}], "href": "https://doi.org/10.1016/j.jmb.2008.04.006"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18462755"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18462755"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Roni H G Wright, Antonios Lioutas, Francois Le Dily, et al. "}, {"type": "b", "children": [{"type": "t", "text": "ADP-ribose-derived nuclear ATP synthesis by NUDIX5 is required for chromatin remodeling."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Science (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1126/science.aad9335"}], "href": "https://doi.org/10.1126/science.aad9335"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27257257"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27257257"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Brent D G Page, Nicholas C K Valerie, Roni H G Wright, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Commun (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41467-017-02293-7"}], "href": "https://doi.org/10.1038/s41467-017-02293-7"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29343827"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29343827"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Toru Ishibashi, Hiroshi Hayakawa, Mutsuo Sekiguchi "}, {"type": "b", "children": [{"type": "t", "text": "A novel mechanism for preventing mutations caused by oxidation of guanine nucleotides."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "EMBO Rep (2003)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/sj.embor.embor838"}], "href": "https://doi.org/10.1038/sj.embor.embor838"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12717453"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12717453"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Hiroyuki Kamiya, Mika Hori, Takao Arimori, et al. "}, {"type": "b", "children": [{"type": "t", "text": "NUDT5 hydrolyzes oxidized deoxyribonucleoside diphosphates with broad substrate specificity."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "DNA Repair (Amst) (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.dnarep.2009.07.011"}], "href": "https://doi.org/10.1016/j.dnarep.2009.07.011"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19699693"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19699693"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Mika Hori, Kazuya Satou, Hideyoshi Harashima, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Suppression of mutagenesis by 8-hydroxy-2'-deoxyguanosine 5'-triphosphate (7,8-dihydro-8-oxo-2'-deoxyguanosine 5'-triphosphate) by human MTH1, MTH2, and NUDT5."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Free Radic Biol Med (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.freeradbiomed.2010.02.002"}], "href": "https://doi.org/10.1016/j.freeradbiomed.2010.02.002"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20144704"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20144704"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Riyoko Ito, Mutsuo Sekiguchi, Daiki Setoyama, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Cleavage of oxidized guanine nucleotide and ADP sugar by human NUDT5 protein."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biochem (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1093/jb/mvr028"}], "href": "https://doi.org/10.1093/jb/mvr028"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21389046"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21389046"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Takao Arimori, Haruhiko Tamaoki, Teruya Nakamura, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Diverse substrate recognition and hydrolysis mechanisms of human NUDT5."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nucleic Acids Res (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1093/nar/gkr575"}], "href": "https://doi.org/10.1093/nar/gkr575"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21768126"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21768126"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Li-Qun Zhang, Da-Peng Dai, Wei Gan, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Lowered nudix type 5 (NUDT5) expression leads to cell cycle retardation in HeLa cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell Biochem (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s11010-011-1190-x"}], "href": "https://doi.org/10.1007/s11010-011-1190-x"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22200976"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22200976"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "L- Q Zhang, X-N Song, D-P Dai, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Lowered Nudix type 5 expression leads to cellular senescence in IMR-90 fibroblast cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Free Radic Res (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3109/10715762.2013.795221"}], "href": "https://doi.org/10.3109/10715762.2013.795221"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23581889"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23581889"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Dan-Ni Li, Cheng-Cheng Yang, Jin Li, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The high expression of MTH1 and NUDT5 promotes tumor metastasis and indicates a poor prognosis in patients with non-small-cell lung cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochim Biophys Acta Mol Cell Res (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.bbamcr.2020.118895"}], "href": "https://doi.org/10.1016/j.bbamcr.2020.118895"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33096144"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33096144"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "He Zhang, Li-Qun Zhang, Cheng-Cheng Yang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The high expression of NUDT5 indicates poor prognosis of breast cancer by modulating AKT / Cyclin D signaling."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PLoS One (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1371/journal.pone.0245876"}], "href": "https://doi.org/10.1371/journal.pone.0245876"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33571243"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33571243"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Dong Tan, Yafei Zhang "}, {"type": "b", "children": [{"type": "t", "text": "Silencing of Nudix type 5 represses proliferation and invasion and enhances chemosensitivity of gastric carcinoma cells by affecting the AKT/GSK-3β/β-catenin pathway."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Toxicol Appl Pharmacol (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.taap.2022.115968"}], "href": "https://doi.org/10.1016/j.taap.2022.115968"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "35247377"}], "href": "https://pubmed.ncbi.nlm.nih.gov/35247377"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Haoran Ding, Chenzhou Wu, Weize Sun, et al. "}, {"type": "b", "children": [{"type": "t", "text": "NUDT5-Determines the fate of head and neck squamous cell carcinoma cells under endoplasmic reticulum stress by catalyzing nuclear ATP production to promote DNA repair."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Oral Oncol (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.oraloncology.2023.106397"}], "href": "https://doi.org/10.1016/j.oraloncology.2023.106397"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "37156197"}], "href": "https://pubmed.ncbi.nlm.nih.gov/37156197"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Jing Qian, Yanxia Ma, William M Tahaney, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The novel phosphatase NUDT5 is a critical regulator of triple-negative breast cancer growth."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Breast Cancer Res (2024)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/s13058-024-01778-w"}], "href": "https://doi.org/10.1186/s13058-024-01778-w"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "38317231"}], "href": "https://pubmed.ncbi.nlm.nih.gov/38317231"}]}]}]}
Synonyms	HYSAH1, YSA1H, YSAH1, YSA1, hNUDT5
Proteins	NUDT5_HUMAN
NCBI Gene ID	11164
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

NUDT5 has 5,521 functional associations with biological entities spanning 9 categories (molecular profile, organism, functional term, phrase or reference, chemical, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 114 datasets.

Click the + buttons to view associations for NUDT5 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

NUDT5 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of NUDT5 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of NUDT5 gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of NUDT5 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of NUDT5 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of NUDT5 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of NUDT5 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of NUDT5 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of NUDT5 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of NUDT5 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of NUDT5 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CCLE Cell Line Proteomics	Cell lines associated with NUDT5 protein from the CCLE Cell Line Proteomics dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with NUDT5 gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of NUDT5 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of NUDT5 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of NUDT5 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing NUDT5 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing NUDT5 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	cellular components containing NUDT5 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with NUDT5 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with NUDT5 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of NUDT5 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with NUDT5 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Chemical Interactions	chemicals interacting with NUDT5 gene/protein from the curated CTD Gene-Chemical Interactions dataset.
	CTD Gene-Disease Associations	diseases associated with NUDT5 gene/protein from the curated CTD Gene-Disease Associations dataset.
	DepMap CRISPR Gene Dependency	cell lines with fitness changed by NUDT5 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	diseases associated with NUDT5 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with NUDT5 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with NUDT5 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with NUDT5 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with NUDT5 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at NUDT5 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of NUDT5 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of NUDT5 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing NUDT5 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
	GeneRIF Biological Term Annotations	biological terms co-occuring with NUDT5 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
	GeneSigDB Published Gene Signatures	PubMedIDs of publications reporting gene signatures containing NUDT5 from the GeneSigDB Published Gene Signatures dataset.
	GEO Signatures of Differentially Expressed Genes for Diseases	disease perturbations changing expression of NUDT5 gene from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.
	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	gene perturbations changing expression of NUDT5 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	kinase perturbations changing expression of NUDT5 gene from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.
	GEO Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of NUDT5 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset.