| HGNC Family | G protein-coupled receptors |
| Name | olfactory receptor, family 51, subfamily E, member 2 |
| Description | Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008] |
| Summary |
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nOR51E2, also known as the prostate‐specific G-protein–coupled receptor (PSGR), is a receptor ectopically expressed in prostate tissues where its activation exerts significant antitumor effects. In prostate cancer cells, binding of ligands such as androstenone derivatives, β-ionone, and endogenous fatty acid metabolites triggers intracellular Ca²⁺ increases and activates mitogen-activated protein kinases, resulting in reduced proliferation, cell cycle arrest, and even neuroendocrine trans-differentiation. Moreover, elevated OR51E2 expression has been detected in early prostate cancer lesions and persists in advanced disease, with its mRNA also being measurable in circulating blood, suggesting its potential utility as a diagnostic and prognostic biomarker. In addition, studies in experimental models have demonstrated that overexpression of OR51E2, particularly in synergy with other genetic lesions like PTEN loss or when released in exosomal form, contributes to altered signaling cascades that may offer novel therapeutic avenues."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "10"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nBeyond the prostate, OR51E2 is also functionally relevant in other tissues. In human epidermal melanocytes, activation by β-ionone leads not only to elevated intracellular Ca²⁺ and cAMP levels but also promotes melanogenesis and dendrite formation while inhibiting cell proliferation. Similarly, in melanoma cells, ligand-induced OR51E2 signaling results in increased Ca²⁺ flux, reduced cell migration, and induction of apoptosis, underscoring its potential role as a therapeutic target. Moreover, in airway smooth muscle, OR51E2 is highly enriched and responds to short-chain fatty acids such as acetate and propionate by slowing cytoskeletal remodeling and cell proliferation. Interestingly, its peripheral expression in tissues like the prostate and lung has been linked to co-expression with proteins such as TMPRSS2, suggesting broader roles in health and disease."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "11", "end_ref": "14"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nHigh-resolution structural and mechanistic studies have further illuminated OR51E2 function. Cryo–electron microscopy has revealed that specific fatty acids, such as propionate, bind within an occluded pocket of OR51E2, where tight packing interactions are essential for receptor activation. Inducible expression studies corroborate that activation of OR51E2 leads to rises in cyclic AMP and downstream activation of cytostatic and apoptotic markers, emphasizing its utility in negatively regulating cell proliferation in a cell context–dependent manner. Together, these insights not only enhance our understanding of OR51E2’s chemical recognition and signaling mechanisms but also support its candidacy as a therapeutic target in diseases such as prostate cancer."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "15"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Jinsheng Weng, Jianghua Wang, Yi Cai, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Increased expression of prostate-specific G-protein-coupled receptor in human prostate intraepithelial neoplasia and prostate cancers."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Int J Cancer (2005)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/ijc.20635"}], "href": "https://doi.org/10.1002/ijc.20635"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15499628"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15499628"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Jinsheng Weng, Wenbin Ma, Dianne Mitchell, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Regulation of human prostate-specific G-protein coupled receptor, PSGR, by two distinct promoters and growth factors."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cell Biochem (2005)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/jcb.20600"}], "href": "https://doi.org/10.1002/jcb.20600"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16149059"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16149059"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "L L Xu, C Sun, G Petrovics, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Quantitative expression profile of PSGR in prostate cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Prostate Cancer Prostatic Dis (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/sj.pcan.4500836"}], "href": "https://doi.org/10.1038/sj.pcan.4500836"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16231015"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16231015"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Jianghua Wang, Jinsheng Weng, Yi Cai, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The prostate-specific G-protein coupled receptors PSGR and PSGR2 are prostate cancer biomarkers that are complementary to alpha-methylacyl-CoA racemase."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Prostate (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/pros.20389"}], "href": "https://doi.org/10.1002/pros.20389"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16491480"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16491480"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Eva M Neuhaus, Weiyi Zhang, Lian Gelis, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Activation of an olfactory receptor inhibits proliferation of prostate cancer cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M109.012096"}], "href": "https://doi.org/10.1074/jbc.M109.012096"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19389702"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19389702"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Heike Wiese, Lian Gelis, Sebastian Wiese, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Quantitative phosphoproteomics reveals the protein tyrosine kinase Pyk2 as a central effector of olfactory receptor signaling in prostate cancer cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochim Biophys Acta (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.bbapap.2014.09.002"}], "href": "https://doi.org/10.1016/j.bbapap.2014.09.002"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25219547"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25219547"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "M Rodriguez, S Siwko, L Zeng, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Prostate-specific G-protein-coupled receptor collaborates with loss of PTEN to promote prostate cancer progression."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Oncogene (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/onc.2015.170"}], "href": "https://doi.org/10.1038/onc.2015.170"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26028029"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26028029"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Marilesia Ferreira de Souza, Hellen Kuasne, Mateus de Camargo Barros-Filho, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Circulating mRNAs and miRNAs as candidate markers for the diagnosis and prognosis of prostate cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PLoS One (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1371/journal.pone.0184094"}], "href": "https://doi.org/10.1371/journal.pone.0184094"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28910345"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28910345"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Tatjana Abaffy, James R Bain, Michael J Muehlbauer, et al. 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"}, {"type": "b", "children": [{"type": "t", "text": "Exosome carrying PSGR promotes stemness and epithelial-mesenchymal transition of low aggressive prostate cancer cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Life Sci (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.lfs.2020.118638"}], "href": "https://doi.org/10.1016/j.lfs.2020.118638"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33164833"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33164833"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Lian Gelis, Nikolina Jovancevic, Sophie Veitinger, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Functional Characterization of the Odorant Receptor 51E2 in Human Melanocytes."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M116.734517"}], "href": "https://doi.org/10.1074/jbc.M116.734517"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27226631"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27226631"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "William H Aisenberg, Jessie Huang, Wanqu Zhu, et al. 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"}, {"type": "b", "children": [{"type": "t", "text": "Co‑expression of peripheral olfactory receptors with SARS‑CoV‑2 infection mediators: Potential implications beyond loss of smell as a COVID‑19 symptom."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Int J Mol Med (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3892/ijmm.2020.4646"}], "href": "https://doi.org/10.3892/ijmm.2020.4646"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32705281"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32705281"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Alexey Pronin, Vladlen Slepak "}, {"type": "b", "children": [{"type": "t", "text": "Ectopically expressed olfactory receptors OR51E1 and OR51E2 suppress proliferation and promote cell death in a prostate cancer cell line."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.jbc.2021.100475"}], "href": "https://doi.org/10.1016/j.jbc.2021.100475"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33640452"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33640452"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Christian B Billesbølle, Claire A de March, Wijnand J C van der Velden, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Structural basis of odorant recognition by a human odorant receptor."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nature (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41586-023-05798-y"}], "href": "https://doi.org/10.1038/s41586-023-05798-y"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "36922591"}], "href": "https://pubmed.ncbi.nlm.nih.gov/36922591"}]}]}]}
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| Synonyms | OR51E3P, PSGR, OR52A2, HPRAJ |
| Proteins | O51E2_HUMAN |
| NCBI Gene ID | 81285 |
| API | |
| Download Associations | |
| Predicted Functions |
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| Co-expressed Genes |
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| Expression in Tissues and Cell Lines |
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OR51E2 has 2,095 functional associations with biological entities spanning 9 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 87 datasets.
Click the + buttons to view associations for OR51E2 from the datasets below.
If available, associations are ranked by standardized value
| Dataset | Summary | |
|---|---|---|
| Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray | tissue samples with high or low expression of OR51E2 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset. | |
| BioGPS Cell Line Gene Expression Profiles | cell lines with high or low expression of OR51E2 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset. | |
| BioGPS Human Cell Type and Tissue Gene Expression Profiles | cell types and tissues with high or low expression of OR51E2 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset. | |
| BioGPS Mouse Cell Type and Tissue Gene Expression Profiles | cell types and tissues with high or low expression of OR51E2 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset. | |
| CCLE Cell Line Gene CNV Profiles | cell lines with high or low copy number of OR51E2 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset. | |
| CCLE Cell Line Gene Expression Profiles | cell lines with high or low expression of OR51E2 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset. | |
| ChEA Transcription Factor Binding Site Profiles | transcription factor binding site profiles with transcription factor binding evidence at the promoter of OR51E2 gene from the CHEA Transcription Factor Binding Site Profiles dataset. | |
| ChEA Transcription Factor Targets | transcription factors binding the promoter of OR51E2 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset. | |
| ChEA Transcription Factor Targets 2022 | transcription factors binding the promoter of OR51E2 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset. | |
| CMAP Signatures of Differentially Expressed Genes for Small Molecules | small molecule perturbations changing expression of OR51E2 gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset. | |
| COMPARTMENTS Curated Protein Localization Evidence Scores | cellular components containing OR51E2 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset. | |
| COMPARTMENTS Curated Protein Localization Evidence Scores 2025 | cellular components containing OR51E2 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset. | |
| COMPARTMENTS Text-mining Protein Localization Evidence Scores | cellular components co-occuring with OR51E2 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset. | |
| COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 | cellular components co-occuring with OR51E2 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset. | |
| COSMIC Cell Line Gene Mutation Profiles | cell lines with OR51E2 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset. | |
| DepMap CRISPR Gene Dependency | cell lines with fitness changed by OR51E2 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset. | |
| DISEASES Experimental Gene-Disease Association Evidence Scores | diseases associated with OR51E2 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset. | |
| DISEASES Experimental Gene-Disease Association Evidence Scores 2025 | diseases associated with OR51E2 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset. | |
| DISEASES Text-mining Gene-Disease Association Evidence Scores | diseases co-occuring with OR51E2 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset. | |
| DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 | diseases co-occuring with OR51E2 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset. | |
| DisGeNET Gene-Disease Associations | diseases associated with OR51E2 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset. | |
| DisGeNET Gene-Phenotype Associations | phenotypes associated with OR51E2 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset. | |
| ENCODE Histone Modification Site Profiles | histone modification site profiles with high histone modification abundance at OR51E2 gene from the ENCODE Histone Modification Site Profiles dataset. | |
| ENCODE Transcription Factor Binding Site Profiles | transcription factor binding site profiles with transcription factor binding evidence at the promoter of OR51E2 gene from the ENCODE Transcription Factor Binding Site Profiles dataset. | |
| ENCODE Transcription Factor Targets | transcription factors binding the promoter of OR51E2 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset. | |
| GDSC Cell Line Gene Expression Profiles | cell lines with high or low expression of OR51E2 gene relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset. | |
| GeneRIF Biological Term Annotations | biological terms co-occuring with OR51E2 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. | |
| GeneSigDB Published Gene Signatures | PubMedIDs of publications reporting gene signatures containing OR51E2 from the GeneSigDB Published Gene Signatures dataset. | |
| GEO Signatures of Differentially Expressed Genes for Diseases | disease perturbations changing expression of OR51E2 gene from the GEO Signatures of Differentially Expressed Genes for Diseases dataset. | |
| GEO Signatures of Differentially Expressed Genes for Gene Perturbations | gene perturbations changing expression of OR51E2 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset. | |
| GEO Signatures of Differentially Expressed Genes for Kinase Perturbations | kinase perturbations changing expression of OR51E2 gene from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset. | |
| GEO Signatures of Differentially Expressed Genes for Small Molecules | small molecule perturbations changing expression of OR51E2 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset. | |
| GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations | transcription factor perturbations changing expression of OR51E2 gene from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset. | |
| GEO Signatures of Differentially Expressed Genes for Viral Infections | virus perturbations changing expression of OR51E2 gene from the GEO Signatures of Differentially Expressed Genes for Viral Infections dataset. | |
| GO Biological Process Annotations 2015 | biological processes involving OR51E2 gene from the curated GO Biological Process Annotations 2015 dataset. | |
| GO Biological Process Annotations 2023 | biological processes involving OR51E2 gene from the curated GO Biological Process Annotations 2023 dataset. | |
| GO Biological Process Annotations 2025 | biological processes involving OR51E2 gene from the curated GO Biological Process Annotations2025 dataset. | |
| GO Cellular Component Annotations 2015 | cellular components containing OR51E2 protein from the curated GO Cellular Component Annotations 2015 dataset. | |
| GO Cellular Component Annotations 2023 | cellular components containing OR51E2 protein from the curated GO Cellular Component Annotations 2023 dataset. | |
| GO Cellular Component Annotations 2025 | cellular components containing OR51E2 protein from the curated GO Cellular Component Annotations 2025 dataset. | |
| GO Molecular Function Annotations 2015 | molecular functions performed by OR51E2 gene from the curated GO Molecular Function Annotations 2015 dataset. | |
| GO Molecular Function Annotations 2023 | molecular functions performed by OR51E2 gene from the curated GO Molecular Function Annotations 2023 dataset. | |
| GO Molecular Function Annotations 2025 | molecular functions performed by OR51E2 gene from the curated GO Molecular Function Annotations 2025 dataset. | |
| GTEx eQTL 2025 | SNPs regulating expression of OR51E2 gene from the GTEx eQTL 2025 dataset. | |
| GTEx Tissue Gene Expression Profiles | tissues with high or low expression of OR51E2 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset. | |
| GTEx Tissue Gene Expression Profiles 2023 | tissues with high or low expression of OR51E2 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles 2023 dataset. | |
| GTEx Tissue Sample Gene Expression Profiles | tissue samples with high or low expression of OR51E2 gene relative to other tissue samples from the GTEx Tissue Sample Gene Expression Profiles dataset. | |
| GTEx Tissue-Specific Aging Signatures | tissue samples with high or low expression of OR51E2 gene relative to other tissue samples from the GTEx Tissue-Specific Aging Signatures dataset. | |
| GWASdb SNP-Disease Associations | diseases associated with OR51E2 gene in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset. | |
| GWASdb SNP-Phenotype Associations | phenotypes associated with OR51E2 gene in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset. | |
| Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles | cell lines with high or low expression of OR51E2 gene relative to other cell lines from the Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles dataset. | |
| HPA Tissue Gene Expression Profiles | tissues with high or low expression of OR51E2 gene relative to other tissues from the HPA Tissue Gene Expression Profiles dataset. | |
| HPA Tissue Sample Gene Expression Profiles | tissue samples with high or low expression of OR51E2 gene relative to other tissue samples from the HPA Tissue Sample Gene Expression Profiles dataset. | |
| HuBMAP ASCT+B Annotations | cell types associated with OR51E2 gene from the HuBMAP ASCT+B dataset. | |
| HuBMAP ASCT+B Augmented with RNA-seq Coexpression | cell types associated with OR51E2 gene from the HuBMAP ASCT+B Augmented with RNA-seq Coexpression dataset. | |
| HuBMAP Azimuth Cell Type Annotations | cell types associated with OR51E2 gene from the HuBMAP Azimuth Cell Type Annotations dataset. | |
| InterPro Predicted Protein Domain Annotations | protein domains predicted for OR51E2 protein from the InterPro Predicted Protein Domain Annotations dataset. | |
| JASPAR Predicted Transcription Factor Targets | transcription factors regulating expression of OR51E2 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset. | |
| Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles | cell lines with high or low copy number of OR51E2 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset. | |
| Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles | cell lines with OR51E2 gene mutations from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset. | |
| KnockTF Gene Expression Profiles with Transcription Factor Perturbations | transcription factor perturbations changing expression of OR51E2 gene from the KnockTF Gene Expression Profiles with Transcription Factor Perturbations dataset. | |
| LINCS L1000 CMAP Chemical Perturbation Consensus Signatures | small molecule perturbations changing expression of OR51E2 gene from the LINCS L1000 CMAP Chemical Perturbations Consensus Signatures dataset. | |
| LINCS L1000 CMAP CRISPR Knockout Consensus Signatures | gene perturbations changing expression of OR51E2 gene from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset. | |
| LOCATE Predicted Protein Localization Annotations | cellular components predicted to contain OR51E2 protein from the LOCATE Predicted Protein Localization Annotations dataset. | |
| MGI Mouse Phenotype Associations 2023 | phenotypes of transgenic mice caused by OR51E2 gene mutations from the MGI Mouse Phenotype Associations 2023 dataset. | |
| MiRTarBase microRNA Targets | microRNAs targeting OR51E2 gene in low- or high-throughput microRNA targeting studies from the MiRTarBase microRNA Targets dataset. | |
| MotifMap Predicted Transcription Factor Targets | transcription factors regulating expression of OR51E2 gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset. | |
| MPO Gene-Phenotype Associations | phenotypes of transgenic mice caused by OR51E2 gene mutations from the MPO Gene-Phenotype Associations dataset. | |
| MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations | gene perturbations changing expression of OR51E2 gene from the MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations dataset. | |
| PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations | gene perturbations changing expression of OR51E2 gene from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset. | |
| PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations | gene perturbations changing expression of OR51E2 gene from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset. | |
| PFOCR Pathway Figure Associations 2024 | pathways involving OR51E2 protein from the Wikipathways PFOCR 2024 dataset. | |
| Reactome Pathways 2014 | pathways involving OR51E2 protein from the Reactome Pathways dataset. | |
| Reactome Pathways 2024 | pathways involving OR51E2 protein from the Reactome Pathways 2024 dataset. | |
| Roadmap Epigenomics Histone Modification Site Profiles | histone modification site profiles with high histone modification abundance at OR51E2 gene from the Roadmap Epigenomics Histone Modification Site Profiles dataset. | |
| RummaGEO Drug Perturbation Signatures | drug perturbations changing expression of OR51E2 gene from the RummaGEO Drug Perturbation Signatures dataset. | |
| RummaGEO Gene Perturbation Signatures | gene perturbations changing expression of OR51E2 gene from the RummaGEO Gene Perturbation Signatures dataset. | |
| Tabula Sapiens Gene-Cell Associations | cell types with high or low expression of OR51E2 gene relative to other cell types from the Tabula Sapiens Gene-Cell Associations dataset. | |
| TargetScan Predicted Conserved microRNA Targets | microRNAs regulating expression of OR51E2 gene predicted using conserved miRNA seed sequences from the TargetScan Predicted Conserved microRNA Targets dataset. | |
| TargetScan Predicted Nonconserved microRNA Targets | microRNAs regulating expression of OR51E2 gene predicted using nonconserved miRNA seed sequences from the TargetScan Predicted Nonconserved microRNA Targets dataset. | |
| TCGA Signatures of Differentially Expressed Genes for Tumors | tissue samples with high or low expression of OR51E2 gene relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset. | |
| TISSUES Curated Tissue Protein Expression Evidence Scores | tissues with high expression of OR51E2 protein from the TISSUES Curated Tissue Protein Expression Evidence Scores dataset. | |
| TISSUES Curated Tissue Protein Expression Evidence Scores 2025 | tissues with high expression of OR51E2 protein from the TISSUES Curated Tissue Protein Expression Evidence Scores 2025 dataset. | |
| TISSUES Experimental Tissue Protein Expression Evidence Scores | tissues with high expression of OR51E2 protein in proteomics datasets from the TISSUES Experimental Tissue Protein Expression Evidence Scores dataset. | |
| TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 | tissues with high expression of OR51E2 protein in proteomics datasets from the TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 dataset. | |
| TISSUES Text-mining Tissue Protein Expression Evidence Scores | tissues co-occuring with OR51E2 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset. | |
| TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 | tissues co-occuring with OR51E2 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 dataset. | |
