PALB2 Gene

HGNC Family	Fanconi anemia, complementation groups (FANC)
Name	partner and localizer of BRCA2
Description	This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the stable intranuclear localization and accumulation of BRCA2. [provided by RefSeq, Jul 2008]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nPALB2 is a central mediator of error‐free repair of DNA double‐strand breaks by homologous recombination. It acts as a molecular scaffold that directly interacts with BRCA1 and BRCA2, thereby promoting the proper localization and stabilization of these tumor suppressors at chromatin. In addition, PALB2 physically binds DNA structures such as D loops and cooperates with the RAD51 recombinase to stimulate strand invasion—a critical step in homologous recombination repair. Through these interactions, PALB2 enables the assembly of multiprotein repair complexes that maintain genome integrity."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "6"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nGermline mutations—often truncating—in PALB2 disrupt its critical role in DNA repair and are associated with a broad spectrum of cancers. Studies have shown that biallelic mutations in PALB2 can lead to Fanconi anemia (designated FANCN/FA‐N) with a concomitant predisposition to early‐onset malignancies, while monoallelic mutations elevate the risk of familial breast cancer, pancreatic cancer, and even occur in male breast cancer. Population studies across different ethnic groups have further established that high‐penetrance PALB2 mutations contribute significantly to hereditary cancer predisposition."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "7", "end_ref": "17"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nCollectively, these findings underscore PALB2’s multifaceted role as a linchpin in the DNA damage response—a function that is crucial not only for orchestrating homologous recombination via its interactions with BRCA1, BRCA2, and RAD51, but also for suppressing tumorigenesis. Impaired PALB2 function, whether through inherited mutations or acquired defects, compromises genomic stability and consequently increases susceptibility to several cancers. As such, PALB2 serves both as an essential guardian of genome integrity and as a clinically relevant biomarker for hereditary cancer risk, with important implications for genetic testing and targeted therapies."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "17"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Bing Xia, Qing Sheng, Koji Nakanishi, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.molcel.2006.05.022"}], "href": "https://doi.org/10.1016/j.molcel.2006.05.022"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16793542"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16793542"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Shirley M H Sy, Michael S Y Huen, Junjie Chen "}, {"type": "b", "children": [{"type": "t", "text": "PALB2 is an integral component of the BRCA complex required for homologous recombination repair."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Proc Natl Acad Sci U S A (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1073/pnas.0811159106"}], "href": "https://doi.org/10.1073/pnas.0811159106"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19369211"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19369211"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Feng Zhang, Jianglin Ma, Jiaxue Wu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "PALB2 links BRCA1 and BRCA2 in the DNA-damage response."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Curr Biol (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.cub.2009.02.018"}], "href": "https://doi.org/10.1016/j.cub.2009.02.018"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19268590"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19268590"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Fan Zhang, Qiang Fan, Keqin Ren, et al. "}, {"type": "b", "children": [{"type": "t", "text": "PALB2 functionally connects the breast cancer susceptibility proteins BRCA1 and BRCA2."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cancer Res (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1158/1541-7786.MCR-09-0123"}], "href": "https://doi.org/10.1158/1541-7786.MCR-09-0123"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19584259"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19584259"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Rémi Buisson, Anne-Marie Dion-Côté, Yan Coulombe, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Cooperation of breast cancer proteins PALB2 and piccolo BRCA2 in stimulating homologous recombination."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Struct Mol Biol (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/nsmb.1915"}], "href": "https://doi.org/10.1038/nsmb.1915"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20871615"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20871615"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Agnieszka Dansonka-Mieszkowska, Anna Kluska, Joanna Moes, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A novel germline PALB2 deletion in Polish breast and ovarian cancer patients."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "BMC Med Genet (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/1471-2350-11-20"}], "href": "https://doi.org/10.1186/1471-2350-11-20"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20122277"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20122277"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Nazneen Rahman, Sheila Seal, Deborah Thompson, et al. "}, {"type": "b", "children": [{"type": "t", "text": "PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Genet (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/ng1959"}], "href": "https://doi.org/10.1038/ng1959"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17200668"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17200668"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Antonis C Antoniou, Silvia Casadei, Tuomas Heikkinen, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Breast-cancer risk in families with mutations in PALB2."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "N Engl J Med (2014)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1056/NEJMoa1400382"}], "href": "https://doi.org/10.1056/NEJMoa1400382"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25099575"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25099575"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Siân Jones, Ralph H Hruban, Mihoko Kamiyama, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Science (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1126/science.1171202"}], "href": "https://doi.org/10.1126/science.1171202"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19264984"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19264984"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Sarah Reid, Detlev Schindler, Helmut Hanenberg, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Genet (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/ng1947"}], "href": "https://doi.org/10.1038/ng1947"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17200671"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17200671"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Hannele Erkko, Bing Xia, Jenni Nikkilä, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A recurrent mutation in PALB2 in Finnish cancer families."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nature (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/nature05609"}], "href": "https://doi.org/10.1038/nature05609"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17287723"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17287723"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Xin Yang, Goska Leslie, Alicja Doroszuk, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Cancer Risks Associated With Germline "}, {"type": "a", "children": [{"type": "t", "text": "i"}], "href": "i"}, {"type": "t", "text": "PALB2"}, {"type": "a", "children": [{"type": "t", "text": "/i"}], "href": "/i"}, {"type": "t", "text": " Pathogenic Variants: An International Study of 524 Families."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Clin Oncol (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1200/JCO.19.01907"}], "href": "https://doi.org/10.1200/JCO.19.01907"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31841383"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31841383"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Silvia Casadei, Barbara M Norquist, Tom Walsh, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Contribution of inherited mutations in the BRCA2-interacting protein PALB2 to familial breast cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Res (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1158/0008-5472.CAN-10-3958"}], "href": "https://doi.org/10.1158/0008-5472.CAN-10-3958"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21285249"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21285249"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "E P Slater, P Langer, E Niemczyk, et al. "}, {"type": "b", "children": [{"type": "t", "text": "PALB2 mutations in European familial pancreatic cancer families."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Clin Genet (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1111/j.1399-0004.2010.01425.x"}], "href": "https://doi.org/10.1111/j.1399-0004.2010.01425.x"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20412113"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20412113"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Marc Tischkowitz, Bing Xia, Nelly Sabbaghian, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Analysis of PALB2/FANCN-associated breast cancer families."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Proc Natl Acad Sci U S A (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1073/pnas.0701724104"}], "href": "https://doi.org/10.1073/pnas.0701724104"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17420451"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17420451"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Yuan Chun Ding, Linda Steele, Chih-Jen Kuan, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Mutations in BRCA2 and PALB2 in male breast cancer cases from the United States."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Breast Cancer Res Treat (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s10549-010-1195-2"}], "href": "https://doi.org/10.1007/s10549-010-1195-2"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20927582"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20927582"}]}, {"type": "r", "ref": 17, "children": [{"type": "t", "text": "Kirsi M Kuusisto, Aleksandra Bebel, Mauno Vihinen, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Screening for BRCA1, BRCA2, CHEK2, PALB2, BRIP1, RAD50, and CDH1 mutations in high-risk Finnish BRCA1/2-founder mutation-negative breast and/or ovarian cancer individuals."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Breast Cancer Res (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/bcr2832"}], "href": "https://doi.org/10.1186/bcr2832"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21356067"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21356067"}]}]}]}
Synonyms	FANCN, PNCA3
Proteins	PALB2_HUMAN
NCBI Gene ID	79728
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

PALB2 has 8,068 functional associations with biological entities spanning 8 categories (molecular profile, organism, chemical, disease, phenotype or trait, functional term, phrase or reference, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 129 datasets.

Click the + buttons to view associations for PALB2 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

PALB2 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of PALB2 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of PALB2 gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of PALB2 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of PALB2 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of PALB2 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of PALB2 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of PALB2 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of PALB2 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of PALB2 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	small molecule perturbations changing expression of PALB2 gene from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of PALB2 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of PALB2 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CCLE Cell Line Gene Mutation Profiles	cell lines with PALB2 gene mutations from the CCLE Cell Line Gene Mutation Profiles dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with PALB2 gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of PALB2 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of PALB2 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of PALB2 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	ClinVar Gene-Phenotype Associations	phenotypes associated with PALB2 gene from the curated ClinVar Gene-Phenotype Associations dataset.
	ClinVar Gene-Phenotype Associations 2025	phenotypes associated with PALB2 gene from the curated ClinVar Gene-Phenotype Associations 2025 dataset.
	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	gene perturbations changing expression of PALB2 gene from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas dataset.
	CM4AI U2OS Cell Map Protein Localization Assemblies	assemblies containing PALB2 protein from integrated AP-MS and IF data from the CM4AI U2OS Cell Map Protein Localization Assemblies dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of PALB2 gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing PALB2 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing PALB2 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores	cellular components containing PALB2 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	cellular components containing PALB2 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with PALB2 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with PALB2 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of PALB2 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with PALB2 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Chemical Interactions	chemicals interacting with PALB2 gene/protein from the curated CTD Gene-Chemical Interactions dataset.
	CTD Gene-Disease Associations	diseases associated with PALB2 gene/protein from the curated CTD Gene-Disease Associations dataset.
	dbGAP Gene-Trait Associations	traits associated with PALB2 gene in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.
	DeepCoverMOA Drug Mechanisms of Action	small molecule perturbations with high or low expression of PALB2 protein relative to other small molecule perturbations from the DeepCoverMOA Drug Mechanisms of Action dataset.
	DepMap CRISPR Gene Dependency	cell lines with fitness changed by PALB2 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
	DGIdb Drug Targets 2026	interacting drugs for PALB2 protein from the DGIdb Drug Targets 2026 dataset.
	DISEASES Curated Gene-Disease Association Evidence Scores	diseases involving PALB2 gene from the DISEASES Curated Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Curated Gene-Disease Association Evidence Scores 2025	diseases involving PALB2 gene from the DISEASES Curated Gene-Disease Association Evidence Scores 2025 dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores	diseases associated with PALB2 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with PALB2 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.