{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nThe collection of abstracts provided does not include any mention of PCNX3. Instead, they consistently focus on the biological functions of the miR‑29 family. In several studies, miR‑29 is shown to serve as a key regulator of extracellular matrix homeostasis – for example, by directly targeting mRNAs that encode major fibrotic proteins (such as multiple collagens, elastin, and other matrix components) to control fibrosis in the heart, lung, liver, kidney, and other tissues. Additionally, dysregulation of miR‑29 is linked to pathological processes ranging from myocardial infarction and diabetic nephropathy to pulmonary fibrosis and skeletal muscle atrophy. These studies emphasize that reduced miR‑29 levels (or loss of its function) result in de‑repression of fibrogenic genes, whereas restoring miR‑29 levels can inhibit fibrosis and even improve tissue function."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "8"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nOther abstracts highlight the role of miR‑29 in modulating cellular processes beyond fibrosis. For instance, miR‑29 has been implicated in the regulation of cell apoptosis, differentiation, and inflammatory responses. In immune cells, altered miR‑29 levels can affect T‑cell polarization and cytokine production, while in neurons and muscle cells, miR‑29 influences survival, atrophy, and developmental pathways. Through targeting key molecules in signaling cascades like TGF‑β/Smad, Wnt, and PI3K/Akt, miR‑29 emerges as a multifaceted modulator in both normal physiology and disease contexts."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "9", "end_ref": "18"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nOther work within the collection further extends the known roles of miR‑29 to include the regulation of epigenetic modifiers, angiogenic factors, and metabolic enzymes, thereby affecting cellular reprogramming, glucose metabolism, and even responses to radiation. Cumulatively, these studies demonstrate that miR‑29 is central to coordinating a wide array of physiological and pathological processes by fine‑tuning the expression of gene networks involved in fibrosis, inflammation, apoptosis, and tissue remodeling. Notably, however, none of the provided abstracts mention or address the function of PCNX3. Thus, while miR‑29 is clearly established as a crucial regulatory molecule in numerous contexts, additional research would be needed to clarify any role for PCNX3 in similar or distinct biological pathways."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "19", "end_ref": "37"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Sébastien S Hébert, Katrien Horré, Laura Nicolaï, et al. 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"}, {"type": "b", "children": [{"type": "t", "text": "MicroRNA-29b is a therapeutic target in cerebral ischemia associated with aquaporin 4."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cereb Blood Flow Metab (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/jcbfm.2015.156"}], "href": "https://doi.org/10.1038/jcbfm.2015.156"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26126866"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26126866"}]}, {"type": "r", "ref": 18, "children": [{"type": "t", "text": "Bo Long, Na Li, Xi-Xia Xu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Long noncoding RNA FTX regulates cardiomyocyte apoptosis by targeting miR-29b-1-5p and Bcl2l2."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem Biophys Res Commun (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.bbrc.2017.11.030"}], "href": "https://doi.org/10.1016/j.bbrc.2017.11.030"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29117536"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29117536"}]}, {"type": "r", "ref": 19, "children": [{"type": "t", "text": "Xudong Guo, Qidong Liu, Guiying Wang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "microRNA-29b is a novel mediator of Sox2 function in the regulation of somatic cell reprogramming."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Res (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/cr.2012.180"}], "href": "https://doi.org/10.1038/cr.2012.180"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23266889"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23266889"}]}, {"type": "r", "ref": 20, "children": [{"type": "t", "text": "Jiayu Zhang, Maochong Chen, Jiawei Chen, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Long non-coding RNA MIAT acts as a biomarker in diabetic retinopathy by absorbing "}, {"type": "a", "children": [{"type": "t", "text": "i"}], "href": "i"}, {"type": "t", "text": "miR-29b"}, {"type": "a", "children": [{"type": "t", "text": "/i"}], "href": "/i"}, {"type": "t", "text": " and regulating cell apoptosis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biosci Rep (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1042/BSR20170036"}], "href": "https://doi.org/10.1042/BSR20170036"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28246353"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28246353"}]}, {"type": "r", "ref": 21, "children": [{"type": "t", "text": "Menaka Chanu Thounaojam, Deepak Kumar Kaushik, Kiran Kundu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "MicroRNA-29b modulates Japanese encephalitis virus-induced microglia activation by targeting tumor necrosis factor alpha-induced protein 3."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Neurochem (2014)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1111/jnc.12609"}], "href": "https://doi.org/10.1111/jnc.12609"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24236890"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24236890"}]}, {"type": "r", "ref": 22, "children": [{"type": "t", "text": "S Jagannathan, N Vad, S Vallabhapurapu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "MiR-29b replacement inhibits proteasomes and disrupts aggresome+autophagosome formation to enhance the antimyeloma benefit of bortezomib."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Leukemia (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/leu.2014.279"}], "href": "https://doi.org/10.1038/leu.2014.279"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25234165"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25234165"}]}, {"type": "r", "ref": 23, "children": [{"type": "t", "text": "Hua-Qing Zhu, Qing li, Liu-Yi Dong, et al. "}, {"type": "b", "children": [{"type": "t", "text": "MicroRNA-29b promotes high-fat diet-stimulated endothelial permeability and apoptosis in apoE knock-out mice by down-regulating MT1 expression."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Int J Cardiol (2014)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.ijcard.2014.07.095"}], "href": "https://doi.org/10.1016/j.ijcard.2014.07.095"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25131924"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25131924"}]}, {"type": "r", "ref": 24, "children": [{"type": "t", "text": "Yumin Zhu, Zhongwu Li, Yanling Wang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Overexpression of miR-29b reduces collagen biosynthesis by inhibiting heat shock protein 47 during skin wound healing."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Transl Res (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.trsl.2016.07.001"}], "href": "https://doi.org/10.1016/j.trsl.2016.07.001"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27477081"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27477081"}]}, {"type": "r", "ref": 25, "children": [{"type": "t", "text": "Xue-Jun Liu, Xue-Ping Zheng, Rui Zhang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Combinatorial effects of miR-20a and miR-29b on neuronal apoptosis induced by spinal cord injury."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Int J Clin Exp Pathol (2015)"}]}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26097563"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26097563"}]}, {"type": "r", "ref": 26, "children": [{"type": "t", "text": "Tao Xue, Li Wei, Ding-Jun Zha, et al. "}, {"type": "b", "children": [{"type": "t", "text": "miR-29b overexpression induces cochlear hair cell apoptosis through the regulation of SIRT1/PGC-1α signaling: Implications for age-related hearing loss."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Int J Mol Med (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3892/ijmm.2016.2735"}], "href": "https://doi.org/10.3892/ijmm.2016.2735"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27635430"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27635430"}]}, {"type": "r", "ref": 27, "children": [{"type": "t", "text": "Rebecca Kohnken, Jing Wen, Bethany Mundy-Bosse, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Diminished microRNA-29b level is associated with BRD4-mediated activation of oncogenes in cutaneous T-cell lymphoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Blood (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1182/blood-2017-09-805663"}], "href": "https://doi.org/10.1182/blood-2017-09-805663"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29180399"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29180399"}]}, {"type": "r", "ref": 28, "children": [{"type": "t", "text": "Gang Li, Jingfeng Zhao, Xianjing Peng, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The mechanism involved in the loss of PTEN expression in NSCLC tumor cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem Biophys Res Commun (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.bbrc.2012.01.065"}], "href": "https://doi.org/10.1016/j.bbrc.2012.01.065"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22290228"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22290228"}]}, {"type": "r", "ref": 29, "children": [{"type": "t", "text": "Kun Zhang, Hong-Xing Cai, Shan Gao, et al. "}, {"type": "b", "children": [{"type": "t", "text": "TNFSF15 suppresses VEGF production in endothelial cells by stimulating miR-29b expression via activation of JNK-GATA3 signals."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Oncotarget (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.18632/oncotarget.11683"}], "href": "https://doi.org/10.18632/oncotarget.11683"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27589684"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27589684"}]}, {"type": "r", "ref": 30, "children": [{"type": "t", "text": "Yanjie Wang, Junhua Zhang, Jian Li, et al. "}, {"type": "b", "children": [{"type": "t", "text": "CircRNA_014511 affects the radiosensitivity of bone marrow mesenchymal stem cells by binding to miR-29b-2-5p."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Bosn J Basic Med Sci (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.17305/bjbms.2019.3935"}], "href": "https://doi.org/10.17305/bjbms.2019.3935"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30640591"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30640591"}]}, {"type": "r", "ref": 31, "children": [{"type": "t", "text": "Yu-Han Hung, Matt Kanke, C Lisa Kurtz, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Acute suppression of insulin resistance-associated hepatic miR-29 in vivo improves glycemic control in adult mice."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Physiol Genomics (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1152/physiolgenomics.00037.2019"}], "href": "https://doi.org/10.1152/physiolgenomics.00037.2019"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31251698"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31251698"}]}, {"type": "r", "ref": 32, "children": [{"type": "t", "text": "Yangyang Kong, Tingjuan Huang, Haiyan Zhang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The lncRNA NEAT1/miR-29b/Atg9a axis regulates IGFBPrP1-induced autophagy and activation of mouse hepatic stellate cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Life Sci (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.lfs.2019.116902"}], "href": "https://doi.org/10.1016/j.lfs.2019.116902"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31610195"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31610195"}]}, {"type": "r", "ref": 33, "children": [{"type": "t", "text": "Jing Zou, Kang-Cheng Liu, Wan-Peng Wang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Circular RNA COL1A2 promotes angiogenesis via regulating miR-29b/VEGF axis in diabetic retinopathy."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Life Sci (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.lfs.2020.117888"}], "href": "https://doi.org/10.1016/j.lfs.2020.117888"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32497630"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32497630"}]}, {"type": "r", "ref": 34, "children": [{"type": "t", "text": "Lan Xiao, Xiang-Xue Ma, Jason Luo, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Circular RNA CircHIPK3 Promotes Homeostasis of the Intestinal Epithelium by Reducing MicroRNA 29b Function."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Gastroenterology (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1053/j.gastro.2021.05.060"}], "href": "https://doi.org/10.1053/j.gastro.2021.05.060"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34116030"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34116030"}]}, {"type": "r", "ref": 35, "children": [{"type": "t", "text": "Jun-Yao Wang, Yu-Hong Cui, Lan Xiao, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Regulation of Intestinal Epithelial Barrier Function by Long Noncoding RNA "}, {"type": "a", "children": [{"type": "t", "text": "i"}], "href": "i"}, {"type": "t", "text": "uc.173"}, {"type": "a", "children": [{"type": "t", "text": "/i"}], "href": "/i"}, {"type": "t", "text": " through Interaction with MicroRNA 29b."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell Biol (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1128/MCB.00010-18"}], "href": "https://doi.org/10.1128/MCB.00010-18"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29632078"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29632078"}]}, {"type": "r", "ref": 36, "children": [{"type": "t", "text": "Christopher A Drummond, Xiaoming Fan, Steven T Haller, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Na/K-ATPase signaling mediates miR-29b-3p regulation and cardiac fibrosis formation in mice with chronic kidney disease."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PLoS One (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1371/journal.pone.0197688"}], "href": "https://doi.org/10.1371/journal.pone.0197688"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29775473"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29775473"}]}, {"type": "r", "ref": 37, "children": [{"type": "t", "text": "N E Calabro, A Barrett, A Chamorro-Jorganes, et al. 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