{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nA survey of the provided abstracts reveals that none of these studies describe or address any function of PLA2G4E. Instead, the collected literature."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "42"}]}, {"type": "t", "text": "\nThese reports collectively focus on the critical roles played by Snail family transcription factors and their cofactors in regulating epithelial‐to‐mesenchymal transition (EMT) in a wide array of physiological and pathological contexts. The studies detail how Snail, along with partnering proteins and signaling pathways (including TGF‑β, WNT, growth factor cascades, and microRNA networks), mediates the suppression of epithelial markers like E‑cadherin and the concomitant induction of mesenchymal features that enhance cell migration, invasion, and survival.\n"}]}, {"type": "t", "text": "\n"}, {"type": "p", "children": [{"type": "t", "text": "\nNotably, while these investigations underscore complex regulatory circuits that govern cell plasticity, metastasis, fibrosis, and developmental processes through EMT modulation, there is no mention or elucidation of PLA2G4E in any of the provided abstracts. This absence indicates that the function of PLA2G4E remains uncharacterized within the context of these studies and suggests that further research is needed to determine whether PLA2G4E might intersect with the EMT pathways or Snail-associated regulatory networks described herein."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "42"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Junichi Ikenouchi, Miho Matsuda, Mikio Furuse, et al. 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