PLGLB1 Gene

Name	plasminogen-like B1
Synonyms	PLGL, PRGB, PRP-B
Proteins	PLGB_HUMAN
NCBI Gene ID	5343
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Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

PLGLB1 has 1,060 functional associations with biological entities spanning 6 categories (molecular profile, organism, functional term, phrase or reference, disease, phenotype or trait, cell line, cell type or tissue, gene, protein or microRNA) extracted from 29 datasets.

Click the + buttons to view associations for PLGLB1 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome

PLGLB1 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference:

Funding

	Dataset	Summary
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of PLGLB1 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of PLGLB1 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	CHEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of PLGLB1 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	CHEA Transcription Factor Targets	transcription factors binding the promoter of PLGLB1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing PLGLB1 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with PLGLB1 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Assocation Evidence Scores	diseases co-occuring with PLGLB1 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of PLGLB1 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of PLGLB1 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	GeneSigDB Published Gene Signatures	PubMedIDs of publications reporting gene signatures containing PLGLB1 from the GeneSigDB Published Gene Signatures dataset.
	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	kinase perturbations changing expression of PLGLB1 gene from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.
	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	transcription factor perturbations changing expression of PLGLB1 gene from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.
	GEO Signatures of Differentially Expressed Genes for Viral Infections	virus perturbations changing expression of PLGLB1 gene from the GEO Signatures of Differentially Expressed Genes for Viral Infections dataset.
	GTEx Tissue Gene Expression Profiles	tissues with high or low expression of PLGLB1 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset.
	GTEx Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of PLGLB1 gene relative to other tissue samples from the GTEx Tissue Sample Gene Expression Profiles dataset.
	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	cell lines with high or low expression of PLGLB1 gene relative to other cell lines from the Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles dataset.
	HPA Cell Line Gene Expression Profiles	cell lines with high or low expression of PLGLB1 gene relative to other cell lines from the HPA Cell Line Gene Expression Profiles dataset.
	HPA Tissue Gene Expression Profiles	tissues with high or low expression of PLGLB1 gene relative to other tissues from the HPA Tissue Gene Expression Profiles dataset.
	HPA Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of PLGLB1 gene relative to other tissue samples from the HPA Tissue Sample Gene Expression Profiles dataset.
	HuGE Navigator Gene-Phenotype Associations	phenotypes associated with PLGLB1 gene by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.
	JASPAR Predicted Transcription Factor Targets	transcription factors regulating expression of PLGLB1 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.
	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	cell lines with high or low copy number of PLGLB1 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.
	Pathway Commons Protein-Protein Interactions	interacting proteins for PLGLB1 from the Pathway Commons Protein-Protein Interactions dataset.
	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of PLGLB1 gene relative to other cell types and tissues from the Roadmap Epigenomics Cell and Tissue Gene Expression Profiles dataset.
	TargetScan Predicted Nonconserved microRNA Targets	microRNAs regulating expression of PLGLB1 gene predicted using nonconserved miRNA seed sequences from the TargetScan Predicted Nonconserved microRNA Targets dataset.
	TISSUES Curated Tissue Protein Expression Evidence Scores	tissues with high expression of PLGLB1 protein from the TISSUES Curated Tissue Protein Expression Evidence Scores dataset.
	TISSUES Experimental Tissue Protein Expression Evidence Scores	tissues with high expression of PLGLB1 protein in proteomics datasets from the TISSUES Experimental Tissue Protein Expression Evidence Scores dataset.
	TISSUES Text-mining Tissue Protein Expression Evidence Scores	tissues co-occuring with PLGLB1 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.
	TRANSFAC Predicted Transcription Factor Targets	transcription factors regulating expression of PLGLB1 gene predicted using known transcription factor binding site motifs from the TRANSFAC Predicted Transcription Factor Targets dataset.