PPM1G Gene

HGNC Family	Phosphatases
Name	protein phosphatase, Mg2+/Mn2+ dependent, 1G
Description	The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression. [provided by RefSeq, Apr 2010]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nPPM1G, a serine/threonine phosphatase, plays a central role in maintaining cellular homeostasis by modulating key processes in response to stress. It is critical for the DNA damage response, for example by dephosphorylating USP7S to drive p53 accumulation under genotoxic stress. In addition, PPM1G is recruited to promoter‐bound 7SK small nuclear ribonucleoprotein (snRNP) complexes where its dephosphorylation activity disassembles these complexes to release P-TEFb and enable gene-specific transcription elongation. Furthermore, PPM1G functions as a histone chaperone by binding and dephosphorylating H2A–H2B dimers, thereby facilitating chromatin remodeling, and it modulates pre-mRNA splicing by altering the phosphorylation states of spliceosomal components such as SRSF3 and the SMN complex."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "6"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nIn addition to its roles in nucleic acid transactions, PPM1G is a key regulator of cell cycle progression and protein synthesis. Its overexpression promotes proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p21—an effect enhanced by Akt signaling—thereby favoring S-phase accumulation. The phosphatase also dephosphorylates 4E-BP1, decreasing its inhibition of cap-dependent translation, and acts as a molecular switch in ubiquitin ligase complexes by controlling the balance between p73 and its N-terminally truncated isoform, ΔNp73. Moreover, by forming a holoenzyme with the PP2A regulatory subunit B56δ, PPM1G directs its activity toward substrates such as α-catenin, thus contributing to the proper assembly of adherens junctions and preventing aberrant cell migration."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "7", "end_ref": "11"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nPPM1G’s multifaceted regulatory actions extend into transcriptional coactivation and cancer-related processes. It functions as a coactivator in the nuclear factor-κB (NF-κB) pathway—a role finely tuned by the tumor suppressor ARF—to ensure the proper magnitude and resolution of inflammatory and survival gene programs. Aberrant expression and epigenetic alterations of the PPM1G gene have been implicated in tumorigenesis across several malignancies, including hepatocellular carcinoma, lung adenocarcinoma, and pancreatic cancer, where high PPM1G levels correlate with poor clinical outcomes. In these contexts, the phosphatase is involved in modulating alternative splicing of cell cycle regulators, directly dephosphorylates upstream kinases such as MEK6 to control p38 MAPK signaling, and promotes autophagy via upregulation of HMGB1. Moreover, altered methylation of PPM1G has been linked to increased risk-taking behavior in alcohol use disorder, emphasizing its broad impact on both cellular physiology and organismal behavior."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "12", "end_ref": "18"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Hiroshi Kimura, Nanako Takizawa, Eric Allemand, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A novel histone exchange factor, protein phosphatase 2Cgamma, mediates the exchange and dephosphorylation of H2A-H2B."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cell Biol (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1083/jcb.200608001"}], "href": "https://doi.org/10.1083/jcb.200608001"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17074886"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17074886"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Eric Allemand, Michelle L Hastings, Michael V Murray, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Alternative splicing regulation by interaction of phosphatase PP2Cgamma with nucleic acid-binding protein YB-1."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Struct Mol Biol (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/nsmb1257"}], "href": "https://doi.org/10.1038/nsmb1257"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17572683"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17572683"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Sebastian Petri, Matthias Grimmler, Sabine Over, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Dephosphorylation of survival motor neurons (SMN) by PPM1G/PP2Cgamma governs Cajal body localization and stability of the SMN complex."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cell Biol (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1083/jcb.200704163"}], "href": "https://doi.org/10.1083/jcb.200704163"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17984321"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17984321"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Svetlana V Khoronenkova, Irina I Dianova, Nicola Ternette, et al. "}, {"type": "b", "children": [{"type": "t", "text": "ATM-dependent downregulation of USP7/HAUSP by PPM1G activates p53 response to DNA damage."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.molcel.2012.01.021"}], "href": "https://doi.org/10.1016/j.molcel.2012.01.021"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22361354"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22361354"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Ryan P McNamara, Jennifer L McCann, Swapna Aravind Gudipaty, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Transcription factors mediate the enzymatic disassembly of promoter-bound 7SK snRNP to locally recruit P-TEFb for transcription elongation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Rep (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.celrep.2013.11.003"}], "href": "https://doi.org/10.1016/j.celrep.2013.11.003"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24316072"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24316072"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Swapna Aravind Gudipaty, Ryan P McNamara, Emily L Morton, et al. "}, {"type": "b", "children": [{"type": "t", "text": "PPM1G Binds 7SK RNA and Hexim1 To Block P-TEFb Assembly into the 7SK snRNP and Sustain Transcription Elongation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell Biol (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1128/MCB.00226-15"}], "href": "https://doi.org/10.1128/MCB.00226-15"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26324325"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26324325"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Eun-Jung Suh, Tae-Yoon Kim, Sang Hoon Kim "}, {"type": "b", "children": [{"type": "t", "text": "PP2Cgamma-mediated S-phase accumulation induced by the proteasome-dependent degradation of p21(WAF1/CIP1)."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "FEBS Lett (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.febslet.2006.10.005"}], "href": "https://doi.org/10.1016/j.febslet.2006.10.005"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17054950"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17054950"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Eun-Jung Suh, Yoon-Jin Kim, Sang Hoon Kim "}, {"type": "b", "children": [{"type": "t", "text": "Protein phosphatase 2Cgamma regulates the level of p21Cip1/WAF1 by Akt signaling."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem Biophys Res Commun (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.bbrc.2009.06.056"}], "href": "https://doi.org/10.1016/j.bbrc.2009.06.056"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19538940"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19538940"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Jianyu Liu, Payton D Stevens, Nichole E Eshleman, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Protein phosphatase PPM1G regulates protein translation and cell growth by dephosphorylating 4E binding protein 1 (4E-BP1)."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M113.492371"}], "href": "https://doi.org/10.1074/jbc.M113.492371"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23814053"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23814053"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Neelam Chaudhary, Subbareddy Maddika "}, {"type": "b", "children": [{"type": "t", "text": "WWP2-WWP1 ubiquitin ligase complex coordinated by PPM1G maintains the balance between cellular p73 and ΔNp73 levels."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell Biol (2014)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1128/MCB.00101-14"}], "href": "https://doi.org/10.1128/MCB.00101-14"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25071155"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25071155"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Parveen Kumar, Prajakta Tathe, Neelam Chaudhary, et al. "}, {"type": "b", "children": [{"type": "t", "text": "PPM1G forms a PPP-type phosphatase holoenzyme with B56δ that maintains adherens junction integrity."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "EMBO Rep (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.15252/embr.201846965"}], "href": "https://doi.org/10.15252/embr.201846965"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31432583"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31432583"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Chun Il Park, Hae Won Kim, Syung Shick Hwang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Association of PPM1G methylation with risk-taking in alcohol use disorder."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Sci Rep (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41598-020-62504-y"}], "href": "https://doi.org/10.1038/s41598-020-62504-y"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32218500"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32218500"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Usman Hyder, Jennifer L McCann, Jinli Wang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The ARF tumor suppressor targets PPM1G/PP2Cγ to counteract NF-κB transcription tuning cell survival and the inflammatory response."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Proc Natl Acad Sci U S A (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1073/pnas.2004470117"}], "href": "https://doi.org/10.1073/pnas.2004470117"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33288725"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33288725"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Yi-Ren Lin, Wen-Jing Yang, Guo-Wang Yang "}, {"type": "b", "children": [{"type": "t", "text": "Prognostic and immunological potential of PPM1G in hepatocellular carcinoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Aging (Albany NY) (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.18632/aging.202964"}], "href": "https://doi.org/10.18632/aging.202964"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33952716"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33952716"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Dan-Lei Xiong, Qian Li, Heng Wang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "High expression of PPM1G is associated with the progression and poor prognosis of hepatocellular carcinoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Biomark (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3233/CBM-203248"}], "href": "https://doi.org/10.3233/CBM-203248"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34366322"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34366322"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Jingying Chen, Jizhuo Li, Hong Sun, et al. "}, {"type": "b", "children": [{"type": "t", "text": "PPM1G promotes the progression of lung adenocarcinoma by inhibiting p38 activation via dephosphorylation of MEK6."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Carcinogenesis (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1093/carcin/bgac090"}], "href": "https://doi.org/10.1093/carcin/bgac090"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "36349938"}], "href": "https://pubmed.ncbi.nlm.nih.gov/36349938"}]}, {"type": "r", "ref": 17, "children": [{"type": "t", "text": "Rongjiang Yin, Li Qu, Zhanqing Wang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Prognostic and immunological potential of PPM1G in lung adenocarcinoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Med Rep (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3892/mmr.2023.13043"}], "href": "https://doi.org/10.3892/mmr.2023.13043"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "37387407"}], "href": "https://pubmed.ncbi.nlm.nih.gov/37387407"}]}, {"type": "r", "ref": 18, "children": [{"type": "t", "text": "Mingyang Song, Min Xu, Qi Zhang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "PPM1G promotes autophagy and progression of pancreatic cancer via upregulating HMGB1."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Signal (2024)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.cellsig.2024.111342"}], "href": "https://doi.org/10.1016/j.cellsig.2024.111342"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "39121976"}], "href": "https://pubmed.ncbi.nlm.nih.gov/39121976"}]}]}]}
Synonyms	PPP2CG, PP2CG, PP2CGAMMA
Proteins	PPM1G_HUMAN
NCBI Gene ID	5496
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

PPM1G has 8,589 functional associations with biological entities spanning 9 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 127 datasets.

Click the + buttons to view associations for PPM1G from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

PPM1G Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Achilles Cell Line Gene Essentiality Profiles	cell lines with fitness changed by PPM1G gene knockdown relative to other cell lines from the Achilles Cell Line Gene Essentiality Profiles dataset.
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of PPM1G gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of PPM1G gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of PPM1G gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of PPM1G gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of PPM1G gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of PPM1G gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of PPM1G gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of PPM1G gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of PPM1G gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	small molecule perturbations changing expression of PPM1G gene from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of PPM1G gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of PPM1G gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CCLE Cell Line Proteomics	Cell lines associated with PPM1G protein from the CCLE Cell Line Proteomics dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with PPM1G gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of PPM1G gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of PPM1G gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of PPM1G gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	CM4AI U2OS Cell Map Protein Localization Assemblies	assemblies containing PPM1G protein from integrated AP-MS and IF data from the CM4AI U2OS Cell Map Protein Localization Assemblies dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of PPM1G gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing PPM1G protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores	cellular components containing PPM1G protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	cellular components containing PPM1G protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with PPM1G protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with PPM1G protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	CORUM Protein Complexes	protein complexs containing PPM1G protein from the CORUM Protein Complexes dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of PPM1G gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with PPM1G gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Chemical Interactions	chemicals interacting with PPM1G gene/protein from the curated CTD Gene-Chemical Interactions dataset.
	CTD Gene-Disease Associations	diseases associated with PPM1G gene/protein from the curated CTD Gene-Disease Associations dataset.
	DepMap CRISPR Gene Dependency	cell lines with fitness changed by PPM1G gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores	diseases associated with PPM1G gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	diseases associated with PPM1G gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with PPM1G gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with PPM1G gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with PPM1G gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with PPM1G gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at PPM1G gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of PPM1G gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of PPM1G gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.