PRAMEF25 Gene

Name PRAME family member 25
Description Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of Cul2-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Mar 2025]
Proteins PRA25_HUMAN
NCBI Gene ID 441873
API
Download Associations
Predicted Functions View PRAMEF25's ARCHS4 Predicted Functions.
Co-expressed Genes View PRAMEF25's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View PRAMEF25's ARCHS4 Predicted Functions.

Functional Associations

PRAMEF25 has 130 functional associations with biological entities spanning 5 categories (disease, phenotype or trait, functional term, phrase or reference, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 7 datasets.

Click the + buttons to view associations for PRAMEF25 from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
CM4AI KOLF21J CRISPRi Gene Perturbation Atlas gene perturbations changing expression of PRAMEF25 gene from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas dataset.
DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 diseases co-occuring with PRAMEF25 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
InterPro Predicted Protein Domain Annotations protein domains predicted for PRAMEF25 protein from the InterPro Predicted Protein Domain Annotations dataset.
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles cell lines with high or low copy number of PRAMEF25 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.
LOCATE Predicted Protein Localization Annotations cellular components predicted to contain PRAMEF25 protein from the LOCATE Predicted Protein Localization Annotations dataset.
NURSA Protein Complexes protein complexs containing PRAMEF25 protein recovered by IP-MS from the NURSA Protein Complexes dataset.
Rummagene Transcription Factor Associations 2026 transcription factors regulating expression of PRAMEF25 gene from the Rummagene Transcription Factor Associations 2026 dataset.