PSG1 Gene

HGNC Family CD molecules (CD), Immunoglobulin superfamily domain containing, Carcinoembryonic antigen family (CEACAM, PSG)
Name pregnancy specific beta-1-glycoprotein 1
Description The human placenta is a multihormonal endocrine organ that produces hormones, enzymes, and other molecules that support fetal survival and development. Pregnancy-specific beta-1-glycoprotein (PSBG, PSG) is a major product of the syncytiotrophoblast, reaching concentrations of 100 to 290 mg/l at term in the serum of pregnant women (Horne et al., 1976 [PubMed 971765]). PSG is a member of the immunoglobulin (Ig) superfamily (Watanabe and Chou, 1988 [PubMed 3257488]; Streydio et al., 1988 [PubMed 3260773]).[supplied by OMIM, Oct 2009]
Summary
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nPregnancy-specific beta-1-glycoprotein 1 (PSG1) plays a critical role during early pregnancy, with evidence pointing to its involvement in implantation and early embryonic development. Messenger RNAs of PSG1 have been detected in mature spermatozoa and may be selectively retained in the zygote, suggesting an early developmental function. In addition, first trimester levels of PSG1 (also referred to as SP1) have been studied as biomarkers for pregnancies with adverse outcomes, and altered PSG1 levels have been associated with conditions such as preeclampsia and hypertensive profiles in pregnancy."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "3"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nBeyond its role in early gestation, PSG1 exhibits potent proangiogenic and immunomodulatory properties. It has been shown to induce transforming growth factor–β1 (TGFB1) and vascular endothelial growth factor A (VEGFA), promoting endothelial tube formation, an activity that is at least partly mediated by its interaction with cell surface glycosaminoglycans. In immunological contexts, PSG1 drives alternative activation of monocytes/macrophages—increasing arginase activity while diminishing nitric oxide production—and enhances regulatory T cell responses by stimulating FOXP3 expression. Furthermore, PSG1 engages in carbohydrate-dependent interactions with lectins such as galectin-1 and other members of the galectin family, which may protect these molecules from oxidative inactivation and fine-tune additional immune responses. Recent findings also indicate that PSG1 can modulate the replicative potential of T cells by down-regulating hTERT expression, thereby contributing to the development of maternal immune tolerance."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "4", "end_ref": "11"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nIn addition to its well‐documented roles at the fetomaternal interface, PSG1 is implicated in several pathological conditions outside of normal pregnancy. Elevated expression of PSG1 has been detected in certain tumors—including squamous cell carcinomas, colonic adenocarcinomas, and gastric cancers—suggesting a potential role in tumor biology and progression. Moreover, PSG1 has been associated with chemoresistance in estrogen receptor–negative breast cancer cells through TGFB-related pathways, and its ectopic expression in nonplacental tissues such as the gastrointestinal tract and even in aging skin fibroblasts highlights its broader relevance as both a biomarker and a modulator of cellular processes across diverse biological systems."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "12", "end_ref": "15"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Conrado Avendaño, Anahí Franchi, Estella Jones, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Pregnancy-specific {beta}-1-glycoprotein 1 and human leukocyte antigen-E mRNA in human sperm: differential expression in fertile and infertile men and evidence of a possible functional role during early development."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Hum Reprod (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1093/humrep/den381"}], "href": "https://doi.org/10.1093/humrep/den381"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18987160"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18987160"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Kasper Pihl, Torben Larsen, Inga Laursen, et al. "}, {"type": "b", "children": [{"type": "t", "text": "First trimester maternal serum pregnancy-specific beta-1-glycoprotein (SP1) as a marker of adverse pregnancy outcome."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Prenat Diagn (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/pd.2408"}], "href": "https://doi.org/10.1002/pd.2408"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19911417"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19911417"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Kenan Toprak, Zafer Yıldız, Selim Akdemir, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Low pregnancy-specific beta-1-glycoprotein is associated with nondipper hypertension and increased risk of preeclampsia in pregnant women with newly diagnosed chronic hypertension."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Scand J Clin Lab Invest (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1080/00365513.2023.2275083"}], "href": "https://doi.org/10.1080/00365513.2023.2275083"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "37887078"}], "href": "https://pubmed.ncbi.nlm.nih.gov/37887078"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Cam T Ha, Julie A Wu, Ster Irmak, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Human pregnancy specific beta-1-glycoprotein 1 (PSG1) has a potential role in placental vascular morphogenesis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biol Reprod (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1095/biolreprod.109.082412"}], "href": "https://doi.org/10.1095/biolreprod.109.082412"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20335639"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20335639"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Claudia Cristina Motrán, Fernando López Díaz, Adriana Gruppi, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Human pregnancy-specific glycoprotein 1a (PSG1a) induces alternative activation in human and mouse monocytes and suppresses the accessory cell-dependent T cell proliferation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Leukoc Biol (2002)"}]}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12223519"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12223519"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Felipe A Lisboa, James Warren, Gisela Sulkowski, et al. 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"}, {"type": "b", "children": [{"type": "t", "text": "The effect of pregnancy-specific β1-glycoprotein 1 on the transcription factor FOXP3 expression by immunocompetent cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Dokl Biochem Biophys (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1134/S1607672916050161"}], "href": "https://doi.org/10.1134/S1607672916050161"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27817017"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27817017"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "S A Zamorina, V P Timganova, M S Bochkova, et al. 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"}, {"type": "b", "children": [{"type": "t", "text": "Effect of Pregnancy Specific β1-Glycoprotein on the Replicative Potential of Naïve T Cells and Immune Memory T Cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Bull Exp Biol Med (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s10517-021-05357-3"}], "href": "https://doi.org/10.1007/s10517-021-05357-3"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34855088"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34855088"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Mirian Mendoza, Angela Ballesteros, Elizabeth Rendon-Correa, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Modulation of galectin-9 mediated responses in monocytes and T-cells by pregnancy-specific glycoprotein 1."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2024)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.jbc.2024.107638"}], "href": "https://doi.org/10.1016/j.jbc.2024.107638"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "39121996"}], "href": "https://pubmed.ncbi.nlm.nih.gov/39121996"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Aileen Houston, John M Williams, Tihana Lenac Rovis, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Pregnancy-specific glycoprotein expression in normal gastrointestinal tract and in tumors detected with novel monoclonal antibodies."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "MAbs (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1080/19420862.2015.1134410"}], "href": "https://doi.org/10.1080/19420862.2015.1134410"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26926266"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26926266"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Dong-Xu He, Feng Gu, Jian Wu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Targeting PSG1 to enhance chemotherapeutic efficacy: new application for anti-coagulant the dicumarol."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Clin Sci (Lond) (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1042/CS20160536"}], "href": "https://doi.org/10.1042/CS20160536"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27653744"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27653744"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Hyeon-Gu Kang, Seok-Jun Kim "}, {"type": "b", "children": [{"type": "t", "text": "High Expression of Pregnancy Specific Beta-1-glycoprotein 1 Is Associated With Poor Gastric Cancer Prognosis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "In Vivo (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.21873/invivo.13005"}], "href": "https://doi.org/10.21873/invivo.13005"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "36309385"}], "href": "https://pubmed.ncbi.nlm.nih.gov/36309385"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Valérie Haydont, Véronique Neiveyans, Hélène Zucchi, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Genome-wide profiling of adult human papillary and reticular fibroblasts identifies ACAN, Col XI α1, and PSG1 as general biomarkers of dermis ageing, and KANK4 as an exemplary effector of papillary fibroblast ageing, related to contractility."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mech Ageing Dev (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.mad.2018.06.003"}], "href": "https://doi.org/10.1016/j.mad.2018.06.003"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29913199"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29913199"}]}]}]}
Synonyms SP1, PBG1, FL-NCA-1/2, PSBG1, B1G1, PSG95, DHFRP2, PS-BETA-C/D, PSBG-1, PS-BETA-G-1, CD66F, PSGIIA, PSGGA
Proteins PSG1_HUMAN
NCBI Gene ID 5669
API
Download Associations
Predicted Functions View PSG1's ARCHS4 Predicted Functions.
Co-expressed Genes View PSG1's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View PSG1's ARCHS4 Predicted Functions.

Functional Associations

PSG1 has 2,259 functional associations with biological entities spanning 8 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 69 datasets.

Click the + buttons to view associations for PSG1 from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray tissue samples with high or low expression of PSG1 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
BioGPS Cell Line Gene Expression Profiles cell lines with high or low expression of PSG1 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
BioGPS Human Cell Type and Tissue Gene Expression Profiles cell types and tissues with high or low expression of PSG1 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
CCLE Cell Line Gene CNV Profiles cell lines with high or low copy number of PSG1 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
CCLE Cell Line Gene Expression Profiles cell lines with high or low expression of PSG1 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
CCLE Cell Line Proteomics Cell lines associated with PSG1 protein from the CCLE Cell Line Proteomics dataset.
ChEA Transcription Factor Binding Site Profiles transcription factor binding site profiles with transcription factor binding evidence at the promoter of PSG1 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
ChEA Transcription Factor Targets transcription factors binding the promoter of PSG1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
ChEA Transcription Factor Targets 2022 transcription factors binding the promoter of PSG1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
CMAP Signatures of Differentially Expressed Genes for Small Molecules small molecule perturbations changing expression of PSG1 gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
COMPARTMENTS Curated Protein Localization Evidence Scores cellular components containing PSG1 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
COMPARTMENTS Text-mining Protein Localization Evidence Scores cellular components co-occuring with PSG1 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
COSMIC Cell Line Gene CNV Profiles cell lines with high or low copy number of PSG1 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
COSMIC Cell Line Gene Mutation Profiles cell lines with PSG1 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
DepMap CRISPR Gene Dependency cell lines with fitness changed by PSG1 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
DISEASES Text-mining Gene-Disease Association Evidence Scores diseases co-occuring with PSG1 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 diseases co-occuring with PSG1 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
DisGeNET Gene-Disease Associations diseases associated with PSG1 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
DisGeNET Gene-Phenotype Associations phenotypes associated with PSG1 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
ENCODE Histone Modification Site Profiles histone modification site profiles with high histone modification abundance at PSG1 gene from the ENCODE Histone Modification Site Profiles dataset.
ENCODE Transcription Factor Binding Site Profiles transcription factor binding site profiles with transcription factor binding evidence at the promoter of PSG1 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
ENCODE Transcription Factor Targets transcription factors binding the promoter of PSG1 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
GDSC Cell Line Gene Expression Profiles cell lines with high or low expression of PSG1 gene relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.
GeneRIF Biological Term Annotations biological terms co-occuring with PSG1 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
GeneSigDB Published Gene Signatures PubMedIDs of publications reporting gene signatures containing PSG1 from the GeneSigDB Published Gene Signatures dataset.
GEO Signatures of Differentially Expressed Genes for Diseases disease perturbations changing expression of PSG1 gene from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.
GEO Signatures of Differentially Expressed Genes for Gene Perturbations gene perturbations changing expression of PSG1 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
GEO Signatures of Differentially Expressed Genes for Kinase Perturbations kinase perturbations changing expression of PSG1 gene from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.
GEO Signatures of Differentially Expressed Genes for Small Molecules small molecule perturbations changing expression of PSG1 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset.
GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations transcription factor perturbations changing expression of PSG1 gene from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.
GEO Signatures of Differentially Expressed Genes for Viral Infections virus perturbations changing expression of PSG1 gene from the GEO Signatures of Differentially Expressed Genes for Viral Infections dataset.
GlyGen Glycosylated Proteins ligands (chemical) binding PSG1 protein from the GlyGen Glycosylated Proteins dataset.
GO Biological Process Annotations 2015 biological processes involving PSG1 gene from the curated GO Biological Process Annotations 2015 dataset.
GO Biological Process Annotations 2023 biological processes involving PSG1 gene from the curated GO Biological Process Annotations 2023 dataset.
GO Cellular Component Annotations 2015 cellular components containing PSG1 protein from the curated GO Cellular Component Annotations 2015 dataset.
GO Cellular Component Annotations 2023 cellular components containing PSG1 protein from the curated GO Cellular Component Annotations 2023 dataset.
GO Molecular Function Annotations 2015 molecular functions performed by PSG1 gene from the curated GO Molecular Function Annotations 2015 dataset.
GO Molecular Function Annotations 2023 molecular functions performed by PSG1 gene from the curated GO Molecular Function Annotations 2023 dataset.
GTEx Tissue Gene Expression Profiles tissues with high or low expression of PSG1 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset.
GTEx Tissue Gene Expression Profiles 2023 tissues with high or low expression of PSG1 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles 2023 dataset.
Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles cell lines with high or low expression of PSG1 gene relative to other cell lines from the Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles dataset.
HPA Cell Line Gene Expression Profiles cell lines with high or low expression of PSG1 gene relative to other cell lines from the HPA Cell Line Gene Expression Profiles dataset.
HPA Tissue Gene Expression Profiles tissues with high or low expression of PSG1 gene relative to other tissues from the HPA Tissue Gene Expression Profiles dataset.
HPA Tissue Protein Expression Profiles tissues with high or low expression of PSG1 protein relative to other tissues from the HPA Tissue Protein Expression Profiles dataset.
HPO Gene-Disease Associations phenotypes associated with PSG1 gene by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.
HuBMAP Azimuth Cell Type Annotations cell types associated with PSG1 gene from the HuBMAP Azimuth Cell Type Annotations dataset.
InterPro Predicted Protein Domain Annotations protein domains predicted for PSG1 protein from the InterPro Predicted Protein Domain Annotations dataset.
JASPAR Predicted Transcription Factor Targets transcription factors regulating expression of PSG1 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles cell lines with high or low copy number of PSG1 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.
KnockTF Gene Expression Profiles with Transcription Factor Perturbations transcription factor perturbations changing expression of PSG1 gene from the KnockTF Gene Expression Profiles with Transcription Factor Perturbations dataset.
LINCS L1000 CMAP Chemical Perturbation Consensus Signatures small molecule perturbations changing expression of PSG1 gene from the LINCS L1000 CMAP Chemical Perturbations Consensus Signatures dataset.
LOCATE Predicted Protein Localization Annotations cellular components predicted to contain PSG1 protein from the LOCATE Predicted Protein Localization Annotations dataset.
MoTrPAC Rat Endurance Exercise Training tissue samples with high or low expression of PSG1 gene relative to other tissue samples from the MoTrPAC Rat Endurance Exercise Training dataset.
MSigDB Cancer Gene Co-expression Modules co-expressed genes for PSG1 from the MSigDB Cancer Gene Co-expression Modules dataset.
Pathway Commons Protein-Protein Interactions interacting proteins for PSG1 from the Pathway Commons Protein-Protein Interactions dataset.
PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations gene perturbations changing expression of PSG1 gene from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations gene perturbations changing expression of PSG1 gene from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
PFOCR Pathway Figure Associations 2023 pathways involving PSG1 protein from the PFOCR Pathway Figure Associations 2023 dataset.
PFOCR Pathway Figure Associations 2024 pathways involving PSG1 protein from the Wikipathways PFOCR 2024 dataset.
Reactome Pathways 2024 pathways involving PSG1 protein from the Reactome Pathways 2024 dataset.
Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles cell types and tissues with high or low DNA methylation of PSG1 gene relative to other cell types and tissues from the Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles dataset.
Roadmap Epigenomics Histone Modification Site Profiles histone modification site profiles with high histone modification abundance at PSG1 gene from the Roadmap Epigenomics Histone Modification Site Profiles dataset.
RummaGEO Drug Perturbation Signatures drug perturbations changing expression of PSG1 gene from the RummaGEO Drug Perturbation Signatures dataset.
RummaGEO Gene Perturbation Signatures gene perturbations changing expression of PSG1 gene from the RummaGEO Gene Perturbation Signatures dataset.
TargetScan Predicted Nonconserved microRNA Targets microRNAs regulating expression of PSG1 gene predicted using nonconserved miRNA seed sequences from the TargetScan Predicted Nonconserved microRNA Targets dataset.
TCGA Signatures of Differentially Expressed Genes for Tumors tissue samples with high or low expression of PSG1 gene relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.
TISSUES Curated Tissue Protein Expression Evidence Scores tissues with high expression of PSG1 protein from the TISSUES Curated Tissue Protein Expression Evidence Scores dataset.
TISSUES Experimental Tissue Protein Expression Evidence Scores tissues with high expression of PSG1 protein in proteomics datasets from the TISSUES Experimental Tissue Protein Expression Evidence Scores dataset.
TISSUES Text-mining Tissue Protein Expression Evidence Scores tissues co-occuring with PSG1 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.