RFX8 Gene

Name	RFX family member 8, lacking RFX DNA binding domain
Proteins	RFX8_HUMAN
NCBI Gene ID	731220
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Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

RFX8 has 1,920 functional associations with biological entities spanning 7 categories (molecular profile, functional term, phrase or reference, disease, phenotype or trait, chemical, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 44 datasets.

Click the + buttons to view associations for RFX8 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome

RFX8 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference:

Funding

	Dataset	Summary
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of RFX8 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of RFX8 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of RFX8 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of RFX8 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of RFX8 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CHEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of RFX8 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	CHEA Transcription Factor Targets	transcription factors binding the promoter of RFX8 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing RFX8 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with RFX8 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	dbGAP Gene-Trait Associations	traits associated with RFX8 gene in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at RFX8 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of RFX8 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of RFX8 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing RFX8 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
	GAD Gene-Disease Associations	diseases associated with RFX8 gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
	GEO Signatures of Differentially Expressed Genes for Diseases	disease perturbations changing expression of RFX8 gene from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.
	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	gene perturbations changing expression of RFX8 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
	GEO Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of RFX8 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset.
	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	transcription factor perturbations changing expression of RFX8 gene from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.
	GO Biological Process Annotations	biological processes involving RFX8 gene from the curated GO Biological Process Annotations dataset.
	GO Cellular Component Annotations	cellular components containing RFX8 protein from the curated GO Cellular Component Annotations dataset.
	GO Molecular Function Annotations	molecular functions performed by RFX8 gene from the curated GO Molecular Function Annotations dataset.
	GTEx Tissue Gene Expression Profiles	tissues with high or low expression of RFX8 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset.
	GTEx Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of RFX8 gene relative to other tissue samples from the GTEx Tissue Sample Gene Expression Profiles dataset.
	GWAS Catalog SNP-Phenotype Associations	phenotypes associated with RFX8 gene in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations dataset.
	GWASdb SNP-Disease Associations	diseases associated with RFX8 gene in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.
	GWASdb SNP-Phenotype Associations	phenotypes associated with RFX8 gene in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.
	HPA Tissue Gene Expression Profiles	tissues with high or low expression of RFX8 gene relative to other tissues from the HPA Tissue Gene Expression Profiles dataset.
	HPA Tissue Protein Expression Profiles	tissues with high or low expression of RFX8 protein relative to other tissues from the HPA Tissue Protein Expression Profiles dataset.
	HPA Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of RFX8 gene relative to other tissue samples from the HPA Tissue Sample Gene Expression Profiles dataset.
	InterPro Predicted Protein Domain Annotations	protein domains predicted for RFX8 protein from the InterPro Predicted Protein Domain Annotations dataset.
	JASPAR Predicted Transcription Factor Targets	transcription factors regulating expression of RFX8 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.
	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	cell lines with high or low copy number of RFX8 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.
	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	cell lines with RFX8 gene mutations from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset.
	MotifMap Predicted Transcription Factor Targets	transcription factors regulating expression of RFX8 gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.
	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	cell types and tissues with high or low DNA methylation of RFX8 gene relative to other cell types and tissues from the Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles dataset.
	Roadmap Epigenomics Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at RFX8 gene from the Roadmap Epigenomics Histone Modification Site Profiles dataset.
	TargetScan Predicted Conserved microRNA Targets	microRNAs regulating expression of RFX8 gene predicted using conserved miRNA seed sequences from the TargetScan Predicted Conserved microRNA Targets dataset.
	TargetScan Predicted Nonconserved microRNA Targets	microRNAs regulating expression of RFX8 gene predicted using nonconserved miRNA seed sequences from the TargetScan Predicted Nonconserved microRNA Targets dataset.
	TCGA Signatures of Differentially Expressed Genes for Tumors	tissue samples with high or low expression of RFX8 gene relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.
	TISSUES Curated Tissue Protein Expression Evidence Scores	tissues with high expression of RFX8 protein from the TISSUES Curated Tissue Protein Expression Evidence Scores dataset.
	TISSUES Experimental Tissue Protein Expression Evidence Scores	tissues with high expression of RFX8 protein in proteomics datasets from the TISSUES Experimental Tissue Protein Expression Evidence Scores dataset.
	TRANSFAC Curated Transcription Factor Targets	transcription factors binding the promoter of RFX8 gene in low- or high-throughput transcription factor functional studies from the TRANSFAC Curated Transcription Factor Targets dataset.
	TRANSFAC Predicted Transcription Factor Targets	transcription factors regulating expression of RFX8 gene predicted using known transcription factor binding site motifs from the TRANSFAC Predicted Transcription Factor Targets dataset.