| HGNC Family | RNA pseudouridylate synthase domain containing (RPUSD) |
| Name | RNA pseudouridylate synthase domain containing 3 |
| Description | This gene encodes a protein that functions in the assembly of the mitochondrial ribosome by adding a pseudouridine group to 16S rRNA. Loss of this gene results in causes defects in mitochondrial protein production. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2017] |
| Summary |
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nA review of the provided abstracts reveals an extensive investigation of imprinted genes, particularly focusing on the GNAS locus and its diverse transcripts (such as Gsα, XLαs, NESP55), along with their roles in receptor‐mediated cyclic AMP signaling, developmental processes, and metabolic regulation. However, none of these studies mention or address the function of RPUSD3. In other words, although the abstracts (for example"}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "22"}]}, {"type": "t", "text": "provide in‐depth details concerning imprinted regulation, receptor trafficking, and G protein–dependent signaling pathways—but they do not include any functional characterization or mention of the RPUSD3 gene.\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nIn summary, despite the breadth of research summarized in these abstracts on key regulatory pathways and genomic imprinting involving GNAS and associated signaling mechanisms, there is no available information here regarding the function of RPUSD3. To elucidate the role, if any, of RPUSD3, additional studies or literature specifically addressing this gene will be necessary.\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "J Peters, S F Wroe, C A Wells, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A cluster of oppositely imprinted transcripts at the Gnas locus in the distal imprinting region of mouse chromosome 2."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Proc Natl Acad Sci U S A (1999)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1073/pnas.96.7.3830"}], "href": "https://doi.org/10.1073/pnas.96.7.3830"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "10097123"}], "href": "https://pubmed.ncbi.nlm.nih.gov/10097123"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Lisa M Mehlmann, Teresa L Z Jones, Laurinda A Jaffe "}, {"type": "b", "children": [{"type": "t", "text": "Meiotic arrest in the mouse follicle maintained by a Gs protein in the oocyte."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Science (2002)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1126/science.1073978"}], "href": "https://doi.org/10.1126/science.1073978"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12193786"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12193786"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Candice Coombes, Philippe Arnaud, Emma Gordon, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Epigenetic properties and identification of an imprint mark in the Nesp-Gnasxl domain of the mouse Gnas imprinted locus."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell Biol (2003)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1128/MCB.23.16.5475-5488.2003"}], "href": "https://doi.org/10.1128/MCB.23.16.5475-5488.2003"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12897124"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12897124"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Travis Harrison, Benjamin U Samuel, Thomas Akompong, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Erythrocyte G protein-coupled receptor signaling in malarial infection."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Science (2003)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1126/science.1089324"}], "href": "https://doi.org/10.1126/science.1089324"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "14500986"}], "href": "https://pubmed.ncbi.nlm.nih.gov/14500986"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Antonius Plagge, Anthony R Isles, Emma Gordon, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Imprinted Nesp55 influences behavioral reactivity to novel environments."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell Biol (2005)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1128/MCB.25.8.3019-3026.2005"}], "href": "https://doi.org/10.1128/MCB.25.8.3019-3026.2005"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15798190"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15798190"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Emily L Germain-Lee, William Schwindinger, Janet L Crane, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A mouse model of albright hereditary osteodystrophy generated by targeted disruption of exon 1 of the Gnas gene."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Endocrinology (2005)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1210/en.2005-0681"}], "href": "https://doi.org/10.1210/en.2005-0681"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16099856"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16099856"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Christine M Williamson, Martin D Turner, Simon T Ball, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Identification of an imprinting control region affecting the expression of all transcripts in the Gnas cluster."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Genet (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/ng1731"}], "href": "https://doi.org/10.1038/ng1731"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16462745"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16462745"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Tao Xie, Antonius Plagge, Oksana Gavrilova, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The alternative stimulatory G protein alpha-subunit XLalphas is a critical regulator of energy and glucose metabolism and sympathetic nerve activity in adult mice."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M511752200"}], "href": "https://doi.org/10.1074/jbc.M511752200"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16672216"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16672216"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Limeng Chen, Soo Mi Kim, Mona Oppermann, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Regulation of renin in mice with Cre recombinase-mediated deletion of G protein Gsalpha in juxtaglomerular cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Am J Physiol Renal Physiol (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1152/ajprenal.00193.2006"}], "href": "https://doi.org/10.1152/ajprenal.00193.2006"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16822937"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16822937"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Yutong Sun, Jianyun Huang, Yang Xiang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Dosage-dependent switch from G protein-coupled to G protein-independent signaling by a GPCR."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "EMBO J (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/sj.emboj.7601502"}], "href": "https://doi.org/10.1038/sj.emboj.7601502"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17170700"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17170700"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Min Chen, Jie Wang, Kathryn E Dickerson, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Central nervous system imprinting of the G protein G(s)alpha and its role in metabolic regulation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Metab (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.cmet.2009.05.004"}], "href": "https://doi.org/10.1016/j.cmet.2009.05.004"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19490909"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19490909"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Yusuke Nagai, Akiyuki Nishimura, Kenji Tago, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Ric-8B stabilizes the alpha subunit of stimulatory G protein by inhibiting its ubiquitination."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M109.063313"}], "href": "https://doi.org/10.1074/jbc.M109.063313"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20133939"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20133939"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Xiangli Li, Fiona Murray, Naoki Koide, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Divergent requirement for Gαs and cAMP in the differentiation and inflammatory profile of distinct mouse Th subsets."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Clin Invest (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1172/JCI59097"}], "href": "https://doi.org/10.1172/JCI59097"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22326954"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22326954"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Min Chen, Alta Berger, Ahmed Kablan, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Gsα deficiency in the paraventricular nucleus of the hypothalamus partially contributes to obesity associated with Gsα mutations."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Endocrinology (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1210/en.2012-1113"}], "href": "https://doi.org/10.1210/en.2012-1113"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22733970"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22733970"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "S Zhang, F S Kaplan, E M Shore "}, {"type": "b", "children": [{"type": "t", "text": "Different roles of GNAS and cAMP signaling during early and late stages of osteogenic differentiation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Horm Metab Res (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1055/s-0032-1321845"}], "href": "https://doi.org/10.1055/s-0032-1321845"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22903279"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22903279"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Jean B Regard, Deepti Malhotra, Jelena Gvozdenovic-Jeremic, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Activation of Hedgehog signaling by loss of GNAS causes heterotopic ossification."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Med (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/nm.3314"}], "href": "https://doi.org/10.1038/nm.3314"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24076664"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24076664"}]}, {"type": "r", "ref": 17, "children": [{"type": "t", "text": "Ramiro Iglesias-Bartolome, Daniela Torres, Romina Marone, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Inactivation of a Gα(s)-PKA tumour suppressor pathway in skin stem cells initiates basal-cell carcinogenesis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Cell Biol (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/ncb3164"}], "href": "https://doi.org/10.1038/ncb3164"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25961504"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25961504"}]}, {"type": "r", "ref": 18, "children": [{"type": "t", "text": "Ansley Semack, Manbir Sandhu, Rabia U Malik, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Structural Elements in the Gαs and Gαq C Termini That Mediate Selective G Protein-coupled Receptor (GPCR) Signaling."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M116.735720"}], "href": "https://doi.org/10.1074/jbc.M116.735720"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27330078"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27330078"}]}, {"type": "r", "ref": 19, "children": [{"type": "t", "text": "Maria Hauge, Jeppe Pio Ekberg, Maja Storm Engelstoft, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Gq and Gs signaling acting in synergy to control GLP-1 secretion."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell Endocrinol (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.mce.2016.11.024"}], "href": "https://doi.org/10.1016/j.mce.2016.11.024"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27908836"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27908836"}]}, {"type": "r", "ref": 20, "children": [{"type": "t", "text": "Amod Godbole, Sandra Lyga, Martin J Lohse, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Internalized TSH receptors en route to the TGN induce local G"}, {"type": "a", "children": [{"type": "t", "text": "sub"}], "href": "sub"}, {"type": "t", "text": "s"}, {"type": "a", "children": [{"type": "t", "text": "/sub"}], "href": "/sub"}, {"type": "t", "text": "-protein signaling and gene transcription."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Commun (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41467-017-00357-2"}], "href": "https://doi.org/10.1038/s41467-017-00357-2"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28874659"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28874659"}]}, {"type": "r", "ref": 21, "children": [{"type": "t", "text": "Krushna C Patra, Yasutaka Kato, Yusuke Mizukami, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Mutant GNAS drives pancreatic tumourigenesis by inducing PKA-mediated SIK suppression and reprogramming lipid metabolism."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Cell Biol (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41556-018-0122-3"}], "href": "https://doi.org/10.1038/s41556-018-0122-3"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29941929"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29941929"}]}, {"type": "r", "ref": 22, "children": [{"type": "t", "text": "Okechi S Oduori, Naoya Murao, Kenju Shimomura, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Gs/Gq signaling switch in β cells defines incretin effectiveness in diabetes."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Clin Invest (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1172/JCI140046"}], "href": "https://doi.org/10.1172/JCI140046"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33196462"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33196462"}]}]}]}
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| Proteins | RUSD3_HUMAN |
| NCBI Gene ID | 285367 |
| API | |
| Download Associations | |
| Predicted Functions |
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| Co-expressed Genes |
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| Expression in Tissues and Cell Lines |
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RPUSD3 has 3,986 functional associations with biological entities spanning 9 categories (molecular profile, organism, functional term, phrase or reference, chemical, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 86 datasets.
Click the + buttons to view associations for RPUSD3 from the datasets below.
If available, associations are ranked by standardized value
| Dataset | Summary | |
|---|---|---|
| Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles | tissues with high or low expression of RPUSD3 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset. | |
| Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray | tissue samples with high or low expression of RPUSD3 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset. | |
| Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq | tissue samples with high or low expression of RPUSD3 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset. | |
| Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles | tissues with high or low expression of RPUSD3 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset. | |
| BioGPS Human Cell Type and Tissue Gene Expression Profiles | cell types and tissues with high or low expression of RPUSD3 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset. | |
| BioGPS Mouse Cell Type and Tissue Gene Expression Profiles | cell types and tissues with high or low expression of RPUSD3 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset. | |
| CCLE Cell Line Gene CNV Profiles | cell lines with high or low copy number of RPUSD3 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset. | |
| CCLE Cell Line Gene Expression Profiles | cell lines with high or low expression of RPUSD3 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset. | |
| CCLE Cell Line Proteomics | Cell lines associated with RPUSD3 protein from the CCLE Cell Line Proteomics dataset. | |
| CellMarker Gene-Cell Type Associations | cell types associated with RPUSD3 gene from the CellMarker Gene-Cell Type Associations dataset. | |
| ChEA Transcription Factor Binding Site Profiles | transcription factor binding site profiles with transcription factor binding evidence at the promoter of RPUSD3 gene from the CHEA Transcription Factor Binding Site Profiles dataset. | |
| ChEA Transcription Factor Targets | transcription factors binding the promoter of RPUSD3 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset. | |
| ChEA Transcription Factor Targets 2022 | transcription factors binding the promoter of RPUSD3 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset. | |
| COMPARTMENTS Curated Protein Localization Evidence Scores 2025 | cellular components containing RPUSD3 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset. | |
| COMPARTMENTS Experimental Protein Localization Evidence Scores | cellular components containing RPUSD3 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores dataset. | |
| COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 | cellular components containing RPUSD3 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 dataset. | |
| COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 | cellular components co-occuring with RPUSD3 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset. | |
| COSMIC Cell Line Gene CNV Profiles | cell lines with high or low copy number of RPUSD3 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset. | |
| COSMIC Cell Line Gene Mutation Profiles | cell lines with RPUSD3 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset. | |
| CTD Gene-Chemical Interactions | chemicals interacting with RPUSD3 gene/protein from the curated CTD Gene-Chemical Interactions dataset. | |
| CTD Gene-Disease Associations | diseases associated with RPUSD3 gene/protein from the curated CTD Gene-Disease Associations dataset. | |
| DeepCoverMOA Drug Mechanisms of Action | small molecule perturbations with high or low expression of RPUSD3 protein relative to other small molecule perturbations from the DeepCoverMOA Drug Mechanisms of Action dataset. | |
| DepMap CRISPR Gene Dependency | cell lines with fitness changed by RPUSD3 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset. | |
| DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 | diseases co-occuring with RPUSD3 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset. | |
| ENCODE Histone Modification Site Profiles | histone modification site profiles with high histone modification abundance at RPUSD3 gene from the ENCODE Histone Modification Site Profiles dataset. | |
| ENCODE Transcription Factor Binding Site Profiles | transcription factor binding site profiles with transcription factor binding evidence at the promoter of RPUSD3 gene from the ENCODE Transcription Factor Binding Site Profiles dataset. | |
| ENCODE Transcription Factor Targets | transcription factors binding the promoter of RPUSD3 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset. | |
| ESCAPE Omics Signatures of Genes and Proteins for Stem Cells | PubMedIDs of publications reporting gene signatures containing RPUSD3 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset. | |
| GeneSigDB Published Gene Signatures | PubMedIDs of publications reporting gene signatures containing RPUSD3 from the GeneSigDB Published Gene Signatures dataset. | |
| GEO Signatures of Differentially Expressed Genes for Diseases | disease perturbations changing expression of RPUSD3 gene from the GEO Signatures of Differentially Expressed Genes for Diseases dataset. | |
| GEO Signatures of Differentially Expressed Genes for Gene Perturbations | gene perturbations changing expression of RPUSD3 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset. | |
| GEO Signatures of Differentially Expressed Genes for Kinase Perturbations | kinase perturbations changing expression of RPUSD3 gene from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset. | |
| GEO Signatures of Differentially Expressed Genes for Small Molecules | small molecule perturbations changing expression of RPUSD3 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset. | |
| GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations | transcription factor perturbations changing expression of RPUSD3 gene from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset. | |
| GEO Signatures of Differentially Expressed Genes for Viral Infections | virus perturbations changing expression of RPUSD3 gene from the GEO Signatures of Differentially Expressed Genes for Viral Infections dataset. | |
| GO Biological Process Annotations 2015 | biological processes involving RPUSD3 gene from the curated GO Biological Process Annotations 2015 dataset. | |
| GO Biological Process Annotations 2023 | biological processes involving RPUSD3 gene from the curated GO Biological Process Annotations 2023 dataset. | |
| GO Biological Process Annotations 2025 | biological processes involving RPUSD3 gene from the curated GO Biological Process Annotations2025 dataset. | |
| GO Cellular Component Annotations 2025 | cellular components containing RPUSD3 protein from the curated GO Cellular Component Annotations 2025 dataset. | |
| GO Molecular Function Annotations 2015 | molecular functions performed by RPUSD3 gene from the curated GO Molecular Function Annotations 2015 dataset. | |
| GO Molecular Function Annotations 2023 | molecular functions performed by RPUSD3 gene from the curated GO Molecular Function Annotations 2023 dataset. | |
| GTEx eQTL 2025 | SNPs regulating expression of RPUSD3 gene from the GTEx eQTL 2025 dataset. | |
| GTEx Tissue Gene Expression Profiles | tissues with high or low expression of RPUSD3 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset. | |
| GTEx Tissue Gene Expression Profiles 2023 | tissues with high or low expression of RPUSD3 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles 2023 dataset. | |
| GTEx Tissue Sample Gene Expression Profiles | tissue samples with high or low expression of RPUSD3 gene relative to other tissue samples from the GTEx Tissue Sample Gene Expression Profiles dataset. | |
| GTEx Tissue-Specific Aging Signatures | tissue samples with high or low expression of RPUSD3 gene relative to other tissue samples from the GTEx Tissue-Specific Aging Signatures dataset. | |
| Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles | cell lines with high or low expression of RPUSD3 gene relative to other cell lines from the Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles dataset. | |
| HMDB Metabolites of Enzymes | interacting metabolites for RPUSD3 protein from the curated HMDB Metabolites of Enzymes dataset. | |
| HPA Cell Line Gene Expression Profiles | cell lines with high or low expression of RPUSD3 gene relative to other cell lines from the HPA Cell Line Gene Expression Profiles dataset. | |
| HPA Tissue Gene Expression Profiles | tissues with high or low expression of RPUSD3 gene relative to other tissues from the HPA Tissue Gene Expression Profiles dataset. | |
| HPA Tissue Protein Expression Profiles | tissues with high or low expression of RPUSD3 protein relative to other tissues from the HPA Tissue Protein Expression Profiles dataset. | |
| HPA Tissue Sample Gene Expression Profiles | tissue samples with high or low expression of RPUSD3 gene relative to other tissue samples from the HPA Tissue Sample Gene Expression Profiles dataset. | |
| IMPC Knockout Mouse Phenotypes | phenotypes of mice caused by RPUSD3 gene knockout from the IMPC Knockout Mouse Phenotypes dataset. | |
| InterPro Predicted Protein Domain Annotations | protein domains predicted for RPUSD3 protein from the InterPro Predicted Protein Domain Annotations dataset. | |
| JASPAR Predicted Transcription Factor Targets | transcription factors regulating expression of RPUSD3 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset. | |
| Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles | cell lines with high or low copy number of RPUSD3 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset. | |
| Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles | cell lines with high or low expression of RPUSD3 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles dataset. | |
| Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles | cell lines with RPUSD3 gene mutations from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset. | |
| KnockTF Gene Expression Profiles with Transcription Factor Perturbations | transcription factor perturbations changing expression of RPUSD3 gene from the KnockTF Gene Expression Profiles with Transcription Factor Perturbations dataset. | |
| LOCATE Predicted Protein Localization Annotations | cellular components predicted to contain RPUSD3 protein from the LOCATE Predicted Protein Localization Annotations dataset. | |
| MGI Mouse Phenotype Associations 2023 | phenotypes of transgenic mice caused by RPUSD3 gene mutations from the MGI Mouse Phenotype Associations 2023 dataset. | |
| MiRTarBase microRNA Targets | microRNAs targeting RPUSD3 gene in low- or high-throughput microRNA targeting studies from the MiRTarBase microRNA Targets dataset. | |
| MotifMap Predicted Transcription Factor Targets | transcription factors regulating expression of RPUSD3 gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset. | |
| NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles | drug perturbations changing expression of RPUSD3 gene from the NIBR DRUG-seq U2OS MoA Box dataset. | |
| Pathway Commons Protein-Protein Interactions | interacting proteins for RPUSD3 from the Pathway Commons Protein-Protein Interactions dataset. | |
| PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations | gene perturbations changing expression of RPUSD3 gene from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset. | |
| PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations | gene perturbations changing expression of RPUSD3 gene from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset. | |
| PFOCR Pathway Figure Associations 2023 | pathways involving RPUSD3 protein from the PFOCR Pathway Figure Associations 2023 dataset. | |
| PFOCR Pathway Figure Associations 2024 | pathways involving RPUSD3 protein from the Wikipathways PFOCR 2024 dataset. | |
| Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures | gene perturbations changing expression of RPUSD3 gene from the Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures dataset. | |
| Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures | gene perturbations changing expression of RPUSD3 gene from the Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures dataset. | |
| Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures | gene perturbations changing expression of RPUSD3 gene from the Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures dataset. | |
| Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles | cell types and tissues with high or low DNA methylation of RPUSD3 gene relative to other cell types and tissues from the Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles dataset. | |
| Roadmap Epigenomics Cell and Tissue Gene Expression Profiles | cell types and tissues with high or low expression of RPUSD3 gene relative to other cell types and tissues from the Roadmap Epigenomics Cell and Tissue Gene Expression Profiles dataset. | |
| Roadmap Epigenomics Histone Modification Site Profiles | histone modification site profiles with high histone modification abundance at RPUSD3 gene from the Roadmap Epigenomics Histone Modification Site Profiles dataset. | |
| RummaGEO Drug Perturbation Signatures | drug perturbations changing expression of RPUSD3 gene from the RummaGEO Drug Perturbation Signatures dataset. | |
| RummaGEO Gene Perturbation Signatures | gene perturbations changing expression of RPUSD3 gene from the RummaGEO Gene Perturbation Signatures dataset. | |
| Sanger Dependency Map Cancer Cell Line Proteomics | cell lines associated with RPUSD3 protein from the Sanger Dependency Map Cancer Cell Line Proteomics dataset. | |
| TargetScan Predicted Conserved microRNA Targets | microRNAs regulating expression of RPUSD3 gene predicted using conserved miRNA seed sequences from the TargetScan Predicted Conserved microRNA Targets dataset. | |
| TargetScan Predicted Nonconserved microRNA Targets | microRNAs regulating expression of RPUSD3 gene predicted using nonconserved miRNA seed sequences from the TargetScan Predicted Nonconserved microRNA Targets dataset. | |
| TCGA Signatures of Differentially Expressed Genes for Tumors | tissue samples with high or low expression of RPUSD3 gene relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset. | |
| TISSUES Curated Tissue Protein Expression Evidence Scores | tissues with high expression of RPUSD3 protein from the TISSUES Curated Tissue Protein Expression Evidence Scores dataset. | |
| TISSUES Curated Tissue Protein Expression Evidence Scores 2025 | tissues with high expression of RPUSD3 protein from the TISSUES Curated Tissue Protein Expression Evidence Scores 2025 dataset. | |
| TISSUES Experimental Tissue Protein Expression Evidence Scores | tissues with high expression of RPUSD3 protein in proteomics datasets from the TISSUES Experimental Tissue Protein Expression Evidence Scores dataset. | |
| TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 | tissues with high expression of RPUSD3 protein in proteomics datasets from the TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 dataset. | |
| TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 | tissues co-occuring with RPUSD3 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 dataset. | |
