RRBP1 Gene

Name	ribosome binding protein 1
Description	This gene encodes a ribosome-binding protein of the endoplasmic reticulum (ER) membrane. Studies suggest that this gene plays a role in ER proliferation, secretory pathways and secretory cell differentiation, and mediation of ER-microtubule interactions. Alternative splicing has been observed and protein isoforms are characterized by regions of N-terminal decapeptide and C-terminal heptad repeats. Splicing of the tandem repeats results in variations in ribosome-binding affinity and secretory function. The full-length nature of variants which differ in repeat length has not been determined. Pseudogenes of this gene have been identified on chromosomes 3 and 7, and RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome, the result of a mutation in a nearby gene on chromosome 20p12. [provided by RefSeq, Apr 2012]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nRRBP1 (also known as p180) is a multifunctional endoplasmic reticulum (ER) membrane protein that was first recognized for its capacity to bind ribosomes and mediate the anchoring of mRNAs to the ER independently of active translation. This mRNA receptor activity facilitates the localized synthesis of secreted and membrane proteins and is integral to the proper organization of the rough ER. In addition, RRBP1 has been shown to physically interact with microtubules and motor proteins—mediated by distinct coiled‐coil domains—and thereby contributes to ER morphology, trans-Golgi network expansion, and overall secretory pathway organization."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "6"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nIn the context of cancer, RRBP1 is frequently overexpressed and appears to support tumor cell survival by modulating the unfolded protein response. For instance, in lung cancer RRBP1 alleviates ER stress by upregulating anti-apoptotic factors such as GRP78, thereby promoting resistance to stress-induced apoptosis. Aberrant RRBP1 expression has also been documented in colorectal, ovarian, cervical, endometrial, and urothelial carcinomas, where its levels correlate with disease progression, poor prognosis, and even chemoresistance. Moreover, transcriptional regulators like E2F1 can modulate RRBP1 expression in hepatocellular carcinoma, underscoring its role as a potentially important oncogene."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "7", "end_ref": "15"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nBeyond its roles in protein biosynthesis and tumor biology, RRBP1 is involved in fine-tuning the secretory capacity of cells by influencing ribosome association with the ER and by determining the quality and destination of proteins entering the secretory pathway. Additionally, cis-acting elements within mRNAs (such as those coding for transmembrane domains) require p180 for effective ER anchoring, linking RRBP1 function to mRNA localization and translation regulation. Recent genetic studies have even implicated RRBP1 in cardiovascular regulation, suggesting that variations in its gene might contribute to altered serum lipoprotein levels and blood pressure, reflecting its emerging importance in diverse physiological processes."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "16"}, {"type": "fg_f", "ref": "13"}, {"type": "fg_f", "ref": "17"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Xianying A Cui, Hui Zhang, Alexander F Palazzo "}, {"type": "b", "children": [{"type": "t", "text": "p180 promotes the ribosome-independent localization of a subset of mRNA to the endoplasmic reticulum."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PLoS Biol (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1371/journal.pbio.1001336"}], "href": "https://doi.org/10.1371/journal.pbio.1001336"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22679391"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22679391"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Kiyoko Ogawa-Goto, Keiko Tanaka, Tomonori Ueno, et al. "}, {"type": "b", "children": [{"type": "t", "text": "p180 is involved in the interaction between the endoplasmic reticulum and microtubules through a novel microtubule-binding and bundling domain."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Biol Cell (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1091/mbc.e06-12-1125"}], "href": "https://doi.org/10.1091/mbc.e06-12-1125"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17634287"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17634287"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Payam Benyamini, Paul Webster, David I Meyer "}, {"type": "b", "children": [{"type": "t", "text": "Knockdown of p180 eliminates the terminal differentiation of a secretory cell line."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Biol Cell (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1091/mbc.e08-07-0682"}], "href": "https://doi.org/10.1091/mbc.e08-07-0682"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19037105"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19037105"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Tomonori Ueno, Keisuke Tanaka, Keiko Kaneko, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Enhancement of procollagen biosynthesis by p180 through augmented ribosome association on the endoplasmic reticulum in response to stimulated secretion."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M109.094607"}], "href": "https://doi.org/10.1074/jbc.M109.094607"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20647306"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20647306"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Russell J Diefenbach, Eve Diefenbach, Mark W Douglas, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The ribosome receptor, p180, interacts with kinesin heavy chain, KIF5B."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem Biophys Res Commun (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.bbrc.2004.05.069"}], "href": "https://doi.org/10.1016/j.bbrc.2004.05.069"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15184079"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15184079"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Ji-Zhong Bai, Euphemia Leung, Hilary Holloway, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Alternatively spliced forms of the P180 ribosome receptor differ in their ability to induce the proliferation of rough endoplasmic reticulum."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Biol Int (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.cellbi.2007.10.002"}], "href": "https://doi.org/10.1016/j.cellbi.2007.10.002"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18083570"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18083570"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "H-Y Tsai, Y-F Yang, A T Wu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Endoplasmic reticulum ribosome-binding protein 1 (RRBP1) overexpression is frequently found in lung cancer patients and alleviates intracellular stress-induced apoptosis through the enhancement of GRP78."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Oncogene (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/onc.2012.514"}], "href": "https://doi.org/10.1038/onc.2012.514"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23318453"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23318453"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Y Pan, F Cao, A Guo, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Endoplasmic reticulum ribosome-binding protein 1, RRBP1, promotes progression of colorectal cancer and predicts an unfavourable prognosis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Br J Cancer (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/bjc.2015.260"}], "href": "https://doi.org/10.1038/bjc.2015.260"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26196185"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26196185"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "G S Krasnov, N Iu Oparina, S L Khankin, et al. "}, {"type": "b", "children": [{"type": "t", "text": "[Colorectal cancer 2D-proteomics: identification of altered protein expression]."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Biol (Mosk) (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1134/s0026893309020186"}], "href": "https://doi.org/10.1134/s0026893309020186"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19425502"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19425502"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Jing Ma, Sujing Ren, Jing Ding, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Expression of RRBP1 in epithelial ovarian cancer and its clinical significance."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biosci Rep (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1042/BSR20190656"}], "href": "https://doi.org/10.1042/BSR20190656"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31285390"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31285390"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Tomonori Ueno, Keiko Kaneko, Harutaka Katano, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Expansion of the trans-Golgi network following activated collagen secretion is supported by a coiled-coil microtubule-bundling protein, p180, on the ER."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Exp Cell Res (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.yexcr.2009.11.009"}], "href": "https://doi.org/10.1016/j.yexcr.2009.11.009"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19932094"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19932094"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Yuan He, Shuai Huang, Ting Cheng, et al. "}, {"type": "b", "children": [{"type": "t", "text": "High glucose may promote the proliferation and metastasis of hepatocellular carcinoma via E2F1/RRBP1 pathway."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Life Sci (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.lfs.2020.117656"}], "href": "https://doi.org/10.1016/j.lfs.2020.117656"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32289433"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32289433"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Shuang Liu, Mu Lin, Hongying Ji, et al. "}, {"type": "b", "children": [{"type": "t", "text": "RRBP1 overexpression is associated with progression and prognosis in endometrial endometrioid adenocarcinoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Diagn Pathol (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/s13000-019-0784-6"}], "href": "https://doi.org/10.1186/s13000-019-0784-6"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30684972"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30684972"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Jiaqi Zhu, Ruixue Zhao, Wei Xu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Correlation between reticulum ribosome-binding protein 1 (RRBP1) overexpression and prognosis in cervical squamous cell carcinoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biosci Trends (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.5582/bst.2020.03136"}], "href": "https://doi.org/10.5582/bst.2020.03136"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32536673"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32536673"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Hao-Lun Luo, Hui-Ying Liu, Yin-Lun Chang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Hypomethylated RRBP1 Potentiates Tumor Malignancy and Chemoresistance in Upper Tract Urothelial Carcinoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Int J Mol Sci (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3390/ijms22168761"}], "href": "https://doi.org/10.3390/ijms22168761"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34445467"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34445467"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Xianying A Cui, Yangjing Zhang, Seo Jung Hong, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Identification of a region within the placental alkaline phosphatase mRNA that mediates p180-dependent targeting to the endoplasmic reticulum."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M113.482505"}], "href": "https://doi.org/10.1074/jbc.M113.482505"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24019514"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24019514"}]}, {"type": "r", "ref": 17, "children": [{"type": "t", "text": "Chu-Hsuan Chiu, Chin-Feng Hsuan, Shih-Hua Lin, et al. "}, {"type": "b", "children": [{"type": "t", "text": "ER ribosomal-binding protein 1 regulates blood pressure and potassium homeostasis by modulating intracellular renin trafficking."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biomed Sci (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/s12929-023-00905-7"}], "href": "https://doi.org/10.1186/s12929-023-00905-7"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "36803854"}], "href": "https://pubmed.ncbi.nlm.nih.gov/36803854"}]}]}]}
Synonyms	ES130, RRp, HES, ES/130
Proteins	RRBP1_HUMAN
NCBI Gene ID	6238
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

RRBP1 has 12,554 functional associations with biological entities spanning 9 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 119 datasets.

Click the + buttons to view associations for RRBP1 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

RRBP1 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of RRBP1 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of RRBP1 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of RRBP1 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of RRBP1 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of RRBP1 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of RRBP1 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of RRBP1 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of RRBP1 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of RRBP1 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CCLE Cell Line Proteomics	Cell lines associated with RRBP1 protein from the CCLE Cell Line Proteomics dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with RRBP1 gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of RRBP1 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of RRBP1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of RRBP1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of RRBP1 gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing RRBP1 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing RRBP1 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores	cellular components containing RRBP1 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	cellular components containing RRBP1 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with RRBP1 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with RRBP1 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of RRBP1 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with RRBP1 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Chemical Interactions	chemicals interacting with RRBP1 gene/protein from the curated CTD Gene-Chemical Interactions dataset.
	CTD Gene-Disease Associations	diseases associated with RRBP1 gene/protein from the curated CTD Gene-Disease Associations dataset.
	DeepCoverMOA Drug Mechanisms of Action	small molecule perturbations with high or low expression of RRBP1 protein relative to other small molecule perturbations from the DeepCoverMOA Drug Mechanisms of Action dataset.
	DepMap CRISPR Gene Dependency	cell lines with fitness changed by RRBP1 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	diseases associated with RRBP1 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with RRBP1 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with RRBP1 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with RRBP1 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with RRBP1 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at RRBP1 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of RRBP1 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of RRBP1 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing RRBP1 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
	GDSC Cell Line Gene Expression Profiles	cell lines with high or low expression of RRBP1 gene relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.
	GeneRIF Biological Term Annotations	biological terms co-occuring with RRBP1 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
	GeneSigDB Published Gene Signatures	PubMedIDs of publications reporting gene signatures containing RRBP1 from the GeneSigDB Published Gene Signatures dataset.
	GEO Signatures of Differentially Expressed Genes for Diseases	disease perturbations changing expression of RRBP1 gene from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.