RTEL1-TNFRSF6B Gene

Name	RTEL1-TNFRSF6B readthrough (NMD candidate)
Description	This locus represents naturally occurring read-through transcription between the neighboring RTEL1 (regulator of telomere elongation helicase 1) and TNFRSF6B (tumor necrosis factor receptor superfamily, member 6b, decoy) genes on chromosome 20. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is unlikely to produce a protein product. [provided by RefSeq, Feb 2011]
NCBI Gene ID	100533107
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Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

RTEL1-TNFRSF6B has 1,323 functional associations with biological entities spanning 4 categories (molecular profile, disease, phenotype or trait, cell line, cell type or tissue, gene, protein or microRNA) extracted from 18 datasets.

Click the + buttons to view associations for RTEL1-TNFRSF6B from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

RTEL1-TNFRSF6B Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Achilles Cell Line Gene Essentiality Profiles	cell lines with fitness changed by RTEL1-TNFRSF6B gene knockdown relative to other cell lines from the Achilles Cell Line Gene Essentiality Profiles dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of RTEL1-TNFRSF6B gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of RTEL1-TNFRSF6B gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of RTEL1-TNFRSF6B gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at RTEL1-TNFRSF6B gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of RTEL1-TNFRSF6B gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of RTEL1-TNFRSF6B gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	HPA Cell Line Gene Expression Profiles	cell lines with high or low expression of RTEL1-TNFRSF6B gene relative to other cell lines from the HPA Cell Line Gene Expression Profiles dataset.
	HPA Tissue Gene Expression Profiles	tissues with high or low expression of RTEL1-TNFRSF6B gene relative to other tissues from the HPA Tissue Gene Expression Profiles dataset.
	HPA Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of RTEL1-TNFRSF6B gene relative to other tissue samples from the HPA Tissue Sample Gene Expression Profiles dataset.
	HuGE Navigator Gene-Phenotype Associations	phenotypes associated with RTEL1-TNFRSF6B gene by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.
	JASPAR Predicted Transcription Factor Targets	transcription factors regulating expression of RTEL1-TNFRSF6B gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.
	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	cell lines with high or low copy number of RTEL1-TNFRSF6B gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.
	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	cell lines with high or low expression of RTEL1-TNFRSF6B gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles dataset.
	MiRTarBase microRNA Targets	microRNAs targeting RTEL1-TNFRSF6B gene in low- or high-throughput microRNA targeting studies from the MiRTarBase microRNA Targets dataset.
	MotifMap Predicted Transcription Factor Targets	transcription factors regulating expression of RTEL1-TNFRSF6B gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.
	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	cell types and tissues with high or low DNA methylation of RTEL1-TNFRSF6B gene relative to other cell types and tissues from the Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles dataset.
	Roadmap Epigenomics Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at RTEL1-TNFRSF6B gene from the Roadmap Epigenomics Histone Modification Site Profiles dataset.