SART3 Gene

HGNC Family	RNA binding motif containing (RBM)
Name	squamous cell carcinoma antigen recognized by T cells 3
Description	The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing. [provided by RefSeq, Jul 2008]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nSART3 (also known as TIP110 or p110) is a key recycling factor for spliceosomal small nuclear ribonucleoproteins. It transiently associates with U6 and U4/U6 snRNPs to promote their reassembly after splicing, a process critically dependent on its RNA recognition motifs, tetratricopeptide repeat (TPR) regions, and a highly conserved HAT domain that targets the protein to Cajal bodies. Moreover, SART3 functions by cooperating with the LSm proteins to bind U6 snRNA, and it is also essential for the recycling of both major and minor spliceosomal components, ensuring the continuous availability of splicing-competent snRNPs."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "4"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nIn addition to its direct role in spliceosome recycling, SART3 functions as a molecular adaptor that recruits deubiquitinating enzymes—most notably USP15 and USP4—to spliceosomal proteins and histone substrates. Through direct interactions (as revealed by crystallographic studies), SART3 enhances USP15/USP4 binding to substrates such as ubH2B and TUT1, thereby facilitating deubiquitination events that link the chromatin state with co-transcriptional splicing. SART3 also exhibits histone chaperone activity and, further, has been implicated in microRNA biogenesis by binding pre‑miR‑34a, thus impacting cell cycle progression."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "5", "end_ref": "11"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nBeyond its central splicing functions, SART3/TIP110 is involved in diverse regulatory pathways that impact cellular differentiation, oncogenesis, and development. It serves as a tumor antigen recognized by cytotoxic T cells and plays a role in modulating nuclear receptor signaling (for example, by negatively regulating androgen receptor activity). Moreover, SART3 is essential for maintaining the pluripotency of embryonic stem cells and proper hematopoietic differentiation through regulation of alternative splicing events (such as OCT4 exon usage) and 3′‑UTR processing. Mutations or deregulated expression of SART3/TIP110 have been associated with malignancies, altered responses to hypoxic stress, and developmental syndromes featuring neurodevelopmental defects and gonadal dysgenesis."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "12", "end_ref": "23"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "David Stanĕk, Stephen D Rader, Mirko Klingauf, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Targeting of U4/U6 small nuclear RNP assembly factor SART3/p110 to Cajal bodies."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cell Biol (2003)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1083/jcb.200210087"}], "href": "https://doi.org/10.1083/jcb.200210087"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12578909"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12578909"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Andrey Damianov, Silke Schreiner, Albrecht Bindereif "}, {"type": "b", "children": [{"type": "t", "text": "Recycling of the U12-type spliceosome requires p110, a component of the U6atac snRNP."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell Biol (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1128/MCB.24.4.1700-1708.2004"}], "href": "https://doi.org/10.1128/MCB.24.4.1700-1708.2004"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "14749385"}], "href": "https://pubmed.ncbi.nlm.nih.gov/14749385"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Jan Medenbach, Silke Schreiner, Sunbin Liu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Human U4/U6 snRNP recycling factor p110: mutational analysis reveals the function of the tetratricopeptide repeat domain in recycling."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell Biol (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1128/MCB.24.17.7392-7401.2004"}], "href": "https://doi.org/10.1128/MCB.24.17.7392-7401.2004"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15314151"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15314151"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Konstantin Licht, Jan Medenbach, Reinhard Lührmann, et al. "}, {"type": "b", "children": [{"type": "t", "text": "3'-cyclic phosphorylation of U6 snRNA leads to recruitment of recycling factor p110 through LSm proteins."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "RNA (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1261/rna.1129608"}], "href": "https://doi.org/10.1261/rna.1129608"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18567812"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18567812"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Lindsey Long, Joseph P Thelen, Melonnie Furgason, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The U4/U6 recycling factor SART3 has histone chaperone activity and associates with USP15 to regulate H2B deubiquitination."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2014)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M114.551754"}], "href": "https://doi.org/10.1074/jbc.M114.551754"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24526689"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24526689"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Joon Kyu Park, Tanuza Das, Eun Joo Song, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Structural basis for recruiting and shuttling of the spliceosomal deubiquitinase USP4 by SART3."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nucleic Acids Res (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1093/nar/gkw218"}], "href": "https://doi.org/10.1093/nar/gkw218"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27060135"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27060135"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Qi Zhang, Rachel Harding, Feng Hou, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Structural Basis of the Recruitment of Ubiquitin-specific Protease USP15 by Spliceosome Recycling Factor SART3."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M116.740787"}], "href": "https://doi.org/10.1074/jbc.M116.740787"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27255711"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27255711"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Tanuza Das, Joon Kyu Park, Jinyoung Park, et al. "}, {"type": "b", "children": [{"type": "t", "text": "USP15 regulates dynamic protein-protein interactions of the spliceosome through deubiquitination of PRP31."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nucleic Acids Res (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1093/nar/gkw1365"}], "href": "https://doi.org/10.1093/nar/gkw1365"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28088760"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28088760"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Emily J Sherman, Dylan C Mitchell, Amanda L Garner "}, {"type": "b", "children": [{"type": "t", "text": "The RNA-binding protein SART3 promotes miR-34a biogenesis and G"}, {"type": "a", "children": [{"type": "t", "text": "sub"}], "href": "sub"}, {"type": "t", "text": "1"}, {"type": "a", "children": [{"type": "t", "text": "/sub"}], "href": "/sub"}, {"type": "t", "text": " cell cycle arrest in lung cancer cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.AC119.010419"}], "href": "https://doi.org/10.1074/jbc.AC119.010419"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31619517"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31619517"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Nobuhisa Kanahara, Yusuke Nakata, Masaomi Iyo "}, {"type": "b", "children": [{"type": "t", "text": "Genetic association study detected misalignment in previous whole exome sequence: association study of ZNF806 and SART3 in tardive dystonia."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Psychiatr Genet (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1097/YPG.0000000000000263"}], "href": "https://doi.org/10.1097/YPG.0000000000000263"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32941384"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32941384"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Jaehyun Kim, Takumi Taketomi, Atsuma Yamada, et al. "}, {"type": "b", "children": [{"type": "t", "text": "USP4 regulates TUT1 ubiquitination status in concert with SART3."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem Biophys Res Commun (2024)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.bbrc.2024.149557"}], "href": "https://doi.org/10.1016/j.bbrc.2024.149557"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "38310689"}], "href": "https://pubmed.ncbi.nlm.nih.gov/38310689"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Teruo Sasatomi, Yuichi Suefuji, Kazuko Matsunaga, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Expression of tumor rejection antigens in colorectal carcinomas."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer (2002)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/cncr.10421"}], "href": "https://doi.org/10.1002/cncr.10421"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "11920522"}], "href": "https://pubmed.ncbi.nlm.nih.gov/11920522"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Ying Liu, Byung Oh Kim, Chinghai Kao, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Tip110, the human immunodeficiency virus type 1 (HIV-1) Tat-interacting protein of 110 kDa as a negative regulator of androgen receptor (AR) transcriptional activation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M314321200"}], "href": "https://doi.org/10.1074/jbc.M314321200"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15031286"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15031286"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Elnisr Rashed Mohamed, Masayasu Naito, Yasunobu Terasaki, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Capability of SART3(109-118) peptide to induce cytotoxic T lymphocytes from prostate cancer patients with HLA class I-A11, -A31 and -A33 alleles."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Int J Oncol (2009)"}]}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19148489"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19148489"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Ying Liu, Man-Ryul Lee, Khalid Timani, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Tip110 maintains expression of pluripotent factors in and pluripotency of human embryonic stem cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Stem Cells Dev (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1089/scd.2011.0512"}], "href": "https://doi.org/10.1089/scd.2011.0512"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22132941"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22132941"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Ying Liu, Khalid Timani, Xuan Ou, et al. "}, {"type": "b", "children": [{"type": "t", "text": "C-MYC controlled TIP110 protein expression regulates OCT4 mRNA splicing in human embryonic stem cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Stem Cells Dev (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1089/scd.2012.0271"}], "href": "https://doi.org/10.1089/scd.2012.0271"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23088399"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23088399"}]}, {"type": "r", "ref": 17, "children": [{"type": "t", "text": "Khalid Amine Timani, Ying Liu, Johnny J He "}, {"type": "b", "children": [{"type": "t", "text": "Tip110 interacts with YB-1 and regulates each other's function."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "BMC Mol Biol (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/1471-2199-14-14"}], "href": "https://doi.org/10.1186/1471-2199-14-14"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23822148"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23822148"}]}, {"type": "r", "ref": 18, "children": [{"type": "t", "text": "Weina Zhao, Ying Liu, Khalid Amine Timani, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Tip110 protein binds to unphosphorylated RNA polymerase II and promotes its phosphorylation and HIV-1 long terminal repeat transcription."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2014)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M113.529784"}], "href": "https://doi.org/10.1074/jbc.M113.529784"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24217245"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24217245"}]}, {"type": "r", "ref": 19, "children": [{"type": "t", "text": "Ying Liu, Xinxin Huang, Khalid Amine Timani, et al. "}, {"type": "b", "children": [{"type": "t", "text": "MicroRNA-124 Targets Tip110 Expression and Regulates Hematopoiesis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Stem Cells Dev (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1089/scd.2015.0030"}], "href": "https://doi.org/10.1089/scd.2015.0030"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25928721"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25928721"}]}, {"type": "r", "ref": 20, "children": [{"type": "t", "text": "Khalid Amine Timani, Ying Liu, Yan Fan, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Tip110 Regulates the Cross Talk between p53 and Hypoxia-Inducible Factor 1α under Hypoxia and Promotes Survival of Cancer Cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell Biol (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1128/MCB.00001-15"}], "href": "https://doi.org/10.1128/MCB.00001-15"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25939381"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25939381"}]}, {"type": "r", "ref": 21, "children": [{"type": "t", "text": "Ying Liu, Xinxin Huang, Khalid A Timani, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Regulation of Constitutive Tip110 Expression in Human Cord Blood CD34"}, {"type": "a", "children": [{"type": "t", "text": "sup"}], "href": "sup"}, {"type": "t", "text": "+"}, {"type": "a", "children": [{"type": "t", "text": "/sup"}], "href": "/sup"}, {"type": "t", "text": " Cells Through Selective Usage of the Proximal and Distal Polyadenylation Sites Within the 3'Untranslated Region."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Stem Cells Dev (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1089/scd.2017.0197"}], "href": "https://doi.org/10.1089/scd.2017.0197"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29583087"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29583087"}]}, {"type": "r", "ref": 22, "children": [{"type": "t", "text": "Khalid Amine Timani, Balázs Győrffy, Ying Liu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Tip110/SART3 regulates IL-8 expression and predicts the clinical outcomes in melanoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cancer (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/s12943-018-0868-z"}], "href": "https://doi.org/10.1186/s12943-018-0868-z"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30119675"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30119675"}]}, {"type": "r", "ref": 23, "children": [{"type": "t", "text": "Katie L Ayers, Stefanie Eggers, Ben N Rollo, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Variants in SART3 cause a spliceosomopathy characterised by failure of testis development and neuronal defects."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Commun (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41467-023-39040-0"}], "href": "https://doi.org/10.1038/s41467-023-39040-0"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "37296101"}], "href": "https://pubmed.ncbi.nlm.nih.gov/37296101"}]}]}]}
Synonyms	RP11-13G14, P110(NRB), TIP110, DSAP1
Proteins	SART3_HUMAN
NCBI Gene ID	9733
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

SART3 has 7,024 functional associations with biological entities spanning 8 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 116 datasets.

Click the + buttons to view associations for SART3 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

SART3 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of SART3 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of SART3 gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of SART3 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of SART3 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of SART3 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of SART3 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of SART3 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of SART3 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of SART3 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	small molecule perturbations changing expression of SART3 gene from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of SART3 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of SART3 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CCLE Cell Line Proteomics	Cell lines associated with SART3 protein from the CCLE Cell Line Proteomics dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of SART3 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of SART3 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of SART3 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of SART3 gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing SART3 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing SART3 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores	cellular components containing SART3 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	cellular components containing SART3 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with SART3 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with SART3 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of SART3 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with SART3 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Chemical Interactions	chemicals interacting with SART3 gene/protein from the curated CTD Gene-Chemical Interactions dataset.
	CTD Gene-Disease Associations	diseases associated with SART3 gene/protein from the curated CTD Gene-Disease Associations dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	diseases associated with SART3 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with SART3 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with SART3 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with SART3 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with SART3 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at SART3 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of SART3 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of SART3 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing SART3 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
	GDSC Cell Line Gene Expression Profiles	cell lines with high or low expression of SART3 gene relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.
	GeneRIF Biological Term Annotations	biological terms co-occuring with SART3 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
	GeneSigDB Published Gene Signatures	PubMedIDs of publications reporting gene signatures containing SART3 from the GeneSigDB Published Gene Signatures dataset.
	GEO Signatures of Differentially Expressed Genes for Diseases	disease perturbations changing expression of SART3 gene from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.