SENP3-EIF4A1 Gene

Name	SENP3-EIF4A1 readthrough (NMD candidate)
Description	This locus represents naturally occurring read-through transcription between the neighboring SUMO1/sentrin/SMT3 specific peptidase 3 (SENP3) and eukaryotic translation initiation factor 4A1 (EIF4A1) genes on chromosome 17. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is thus unlikely to produce a protein product. [provided by RefSeq, Mar 2011]
NCBI Gene ID	100533955
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Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

SENP3-EIF4A1 has 1,841 functional associations with biological entities spanning 4 categories (molecular profile, chemical, cell line, cell type or tissue, gene, protein or microRNA) extracted from 15 datasets.

Click the + buttons to view associations for SENP3-EIF4A1 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

SENP3-EIF4A1 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Achilles Cell Line Gene Essentiality Profiles	cell lines with fitness changed by SENP3-EIF4A1 gene knockdown relative to other cell lines from the Achilles Cell Line Gene Essentiality Profiles dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of SENP3-EIF4A1 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of SENP3-EIF4A1 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at SENP3-EIF4A1 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of SENP3-EIF4A1 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of SENP3-EIF4A1 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	GEO Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of SENP3-EIF4A1 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset.
	GTEx Tissue Gene Expression Profiles	tissues with high or low expression of SENP3-EIF4A1 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset.
	GTEx Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of SENP3-EIF4A1 gene relative to other tissue samples from the GTEx Tissue Sample Gene Expression Profiles dataset.
	JASPAR Predicted Transcription Factor Targets	transcription factors regulating expression of SENP3-EIF4A1 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.
	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	cell lines with high or low copy number of SENP3-EIF4A1 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.
	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	cell lines with high or low expression of SENP3-EIF4A1 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles dataset.
	MotifMap Predicted Transcription Factor Targets	transcription factors regulating expression of SENP3-EIF4A1 gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.
	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	cell types and tissues with high or low DNA methylation of SENP3-EIF4A1 gene relative to other cell types and tissues from the Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles dataset.
	Roadmap Epigenomics Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at SENP3-EIF4A1 gene from the Roadmap Epigenomics Histone Modification Site Profiles dataset.