SERPINB11 Gene

HGNC Family	Serpin peptidase inhibitors (SERPIN)
Name	serpin peptidase inhibitor, clade B (ovalbumin), member 11 (gene/pseudogene)
Synonyms	EPIPIN, SERPIN11
Proteins	SPB11_HUMAN
NCBI Gene ID	89778
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Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

SERPINB11 has 1,192 functional associations with biological entities spanning 8 categories (molecular profile, organism, functional term, phrase or reference, disease, phenotype or trait, chemical, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 46 datasets.

Click the + buttons to view associations for SERPINB11 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome

SERPINB11 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference:

Funding

	Dataset	Summary
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of SERPINB11 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of SERPINB11 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of SERPINB11 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of SERPINB11 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of SERPINB11 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CHEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of SERPINB11 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	CHEA Transcription Factor Targets	transcription factors binding the promoter of SERPINB11 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing SERPINB11 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with SERPINB11 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of SERPINB11 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with SERPINB11 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Disease Associations	diseases associated with SERPINB11 gene/protein from the curated CTD Gene-Disease Associations dataset.
	dbGAP Gene-Trait Associations	traits associated with SERPINB11 gene in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.
	DISEASES Text-mining Gene-Disease Assocation Evidence Scores	diseases co-occuring with SERPINB11 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at SERPINB11 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of SERPINB11 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of SERPINB11 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing SERPINB11 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
	GAD Gene-Disease Associations	diseases associated with SERPINB11 gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
	GAD High Level Gene-Disease Associations	diseases associated with SERPINB11 gene in GWAS and other genetic association datasets from the GAD High Level Gene-Disease Associations dataset.
	GeneRIF Biological Term Annotations	biological terms co-occuring with SERPINB11 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
	GeneSigDB Published Gene Signatures	PubMedIDs of publications reporting gene signatures containing SERPINB11 from the GeneSigDB Published Gene Signatures dataset.
	GEO Signatures of Differentially Expressed Genes for Diseases	disease perturbations changing expression of SERPINB11 gene from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.
	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	gene perturbations changing expression of SERPINB11 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	kinase perturbations changing expression of SERPINB11 gene from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.
	GEO Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of SERPINB11 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset.
	GEO Signatures of Differentially Expressed Genes for Viral Infections	virus perturbations changing expression of SERPINB11 gene from the GEO Signatures of Differentially Expressed Genes for Viral Infections dataset.
	GO Biological Process Annotations	biological processes involving SERPINB11 gene from the curated GO Biological Process Annotations dataset.
	GO Cellular Component Annotations	cellular components containing SERPINB11 protein from the curated GO Cellular Component Annotations dataset.
	GO Molecular Function Annotations	molecular functions performed by SERPINB11 gene from the curated GO Molecular Function Annotations dataset.
	GTEx Tissue Gene Expression Profiles	tissues with high or low expression of SERPINB11 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset.
	GTEx Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of SERPINB11 gene relative to other tissue samples from the GTEx Tissue Sample Gene Expression Profiles dataset.
	GWASdb SNP-Disease Associations	diseases associated with SERPINB11 gene in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.
	GWASdb SNP-Phenotype Associations	phenotypes associated with SERPINB11 gene in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.
	InterPro Predicted Protein Domain Annotations	protein domains predicted for SERPINB11 protein from the InterPro Predicted Protein Domain Annotations dataset.
	JASPAR Predicted Transcription Factor Targets	transcription factors regulating expression of SERPINB11 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.
	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	cell lines with high or low copy number of SERPINB11 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.
	MotifMap Predicted Transcription Factor Targets	transcription factors regulating expression of SERPINB11 gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.
	Roadmap Epigenomics Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at SERPINB11 gene from the Roadmap Epigenomics Histone Modification Site Profiles dataset.
	TargetScan Predicted Nonconserved microRNA Targets	microRNAs regulating expression of SERPINB11 gene predicted using nonconserved miRNA seed sequences from the TargetScan Predicted Nonconserved microRNA Targets dataset.
	TCGA Signatures of Differentially Expressed Genes for Tumors	tissue samples with high or low expression of SERPINB11 gene relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.
	TISSUES Curated Tissue Protein Expression Evidence Scores	tissues with high expression of SERPINB11 protein from the TISSUES Curated Tissue Protein Expression Evidence Scores dataset.
	TISSUES Experimental Tissue Protein Expression Evidence Scores	tissues with high expression of SERPINB11 protein in proteomics datasets from the TISSUES Experimental Tissue Protein Expression Evidence Scores dataset.
	TISSUES Text-mining Tissue Protein Expression Evidence Scores	tissues co-occuring with SERPINB11 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.
	TRANSFAC Curated Transcription Factor Targets	transcription factors binding the promoter of SERPINB11 gene in low- or high-throughput transcription factor functional studies from the TRANSFAC Curated Transcription Factor Targets dataset.
	TRANSFAC Predicted Transcription Factor Targets	transcription factors regulating expression of SERPINB11 gene predicted using known transcription factor binding site motifs from the TRANSFAC Predicted Transcription Factor Targets dataset.