SMTN Gene

Name	smoothelin
Description	This gene encodes a structural protein that is found exclusively in contractile smooth muscle cells. It associates with stress fibers and constitutes part of the cytoskeleton. This gene is localized to chromosome 22q12.3, distal to the TUPLE1 locus and outside the DiGeorge syndrome deletion. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2011]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nSmoothelin, the protein product of the SMTN gene, is a specialized cytoskeletal component expressed exclusively in terminally differentiated smooth muscle cells. Its expression is robust in contractile cells of the bladder muscularis propria and the gastrointestinal muscularis propria, while it is weak or absent in proliferative smooth muscle cells, myofibroblasts, and the muscularis mucosae. This highly specific staining pattern makes smoothelin a valuable immunohistochemical marker for distinguishing smooth muscle from morphologic mimics in diagnostic pathology. Its differential expression facilitates accurate tumor staging by helping to discriminate between true muscular layers and reactive or desmoplastic stromal areas in conditions such as bladder carcinoma and colonic adenocarcinoma, as well as in the evaluation of gastrointestinal lesions and leiomyomatous versus stromal neoplasms."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "13"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nBeyond its diagnostic utility, smoothelin is emerging as a key player in vascular physiology and pathology. Genetic studies have revealed that specific SMTN haplotypes are associated with cardiovascular disorders, including essential hypertension, cerebral infarction, and myocardial infarction, thereby underscoring the importance of proper smoothelin expression in the maintenance of smooth muscle contractile function and vascular integrity. In addition, altered smoothelin expression has been implicated in fibrotic conditions—suggesting that the protein’s modulation may influence extracellular matrix interactions and smooth muscle cell phenotype transitions critical to disease processes."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "14", "end_ref": "18"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Leona Council, Omar Hameed "}, {"type": "b", "children": [{"type": "t", "text": "Differential expression of immunohistochemical markers in bladder smooth muscle and myofibroblasts, and the potential utility of desmin, smoothelin, and vimentin in staging of bladder carcinoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mod Pathol (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/modpathol.2009.9"}], "href": "https://doi.org/10.1038/modpathol.2009.9"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19252475"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19252475"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Dominique P Coco, Michelle S Hirsch, Jason L Hornick "}, {"type": "b", "children": [{"type": "t", "text": "Smoothelin is a specific marker for smooth muscle neoplasms of the gastrointestinal tract."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Am J Surg Pathol (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1097/pas.0b013e3181b76477"}], "href": "https://doi.org/10.1097/pas.0b013e3181b76477"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19950405"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19950405"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Hiroshi Miyamoto, Rajni B Sharma, Peter B Illei, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Pitfalls in the use of smoothelin to identify muscularis propria invasion by urothelial carcinoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Am J Surg Pathol (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1097/PAS.0b013e3181ce5066"}], "href": "https://doi.org/10.1097/PAS.0b013e3181ce5066"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20154589"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20154589"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Ian M Bovio, Samer Z Al-Quran, Charles J Rosser, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Smoothelin immunohistochemistry is a useful adjunct for assessing muscularis propria invasion in bladder carcinoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Histopathology (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1111/j.1365-2559.2010.03575.x"}], "href": "https://doi.org/10.1111/j.1365-2559.2010.03575.x"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20636795"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20636795"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Matteo Montani, Thore Thiesler, Glen Kristiansen "}, {"type": "b", "children": [{"type": "t", "text": "Smoothelin is a specific and robust marker for distinction of muscularis propria and muscularis mucosae in the gastrointestinal tract."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Histopathology (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1111/j.1365-2559.2010.03618.x"}], "href": "https://doi.org/10.1111/j.1365-2559.2010.03618.x"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20716166"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20716166"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Hala F Faragalla, Norman E Marcon, George M Yousef, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Immunohistochemical staining for smoothelin in the duplicated versus the true muscularis mucosae of Barrett esophagus."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Am J Surg Pathol (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1097/PAS.0b013e3182035fb6"}], "href": "https://doi.org/10.1097/PAS.0b013e3182035fb6"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21164287"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21164287"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "José Aneiros-Fernández, Husein Husein-ElAhmed, Salvador Arias-Santiago, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Expression of smoothelin and smooth muscle actin in the skin."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Histol Histopathol (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.14670/HH-26.673"}], "href": "https://doi.org/10.14670/HH-26.673"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21472682"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21472682"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Donna E Hansel, Gladell P Paner, Nalan Nese, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Limited smoothelin expression within the muscularis mucosae: validation in bladder diverticula."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Hum Pathol (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.humpath.2011.02.022"}], "href": "https://doi.org/10.1016/j.humpath.2011.02.022"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21683983"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21683983"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Owen T M Chan, Lauren Chiles, Mary Levy, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Smoothelin expression in the gastrointestinal tract: implication in colonic inertia."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Appl Immunohistochem Mol Morphol (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1097/PAI.0b013e31827387c9"}], "href": "https://doi.org/10.1097/PAI.0b013e31827387c9"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23060305"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23060305"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Newton A C S Wong, Jenny Wingate, Richard Colling "}, {"type": "b", "children": [{"type": "t", "text": "A study of α5 chain of collagen IV, caldesmon, placental alkaline phosphatase and smoothelin as immunohistochemical markers of gastrointestinal smooth muscle neoplasms."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Clin Pathol (2014)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1136/jclinpath-2013-201797"}], "href": "https://doi.org/10.1136/jclinpath-2013-201797"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24043717"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24043717"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Jordan A Roberts, Lindsay Waters, Jae Y Ro, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Smoothelin and caldesmon are reliable markers for distinguishing muscularis propria from desmoplasia: a critical distinction for accurate staging colorectal adenocarcinoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Int J Clin Exp Pathol (2014)"}]}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24551305"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24551305"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Jose Aneiros-Fernandez, Juan Antonio Retamero, Husein Husein-ElAhmed, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Smoothelin and WT-1 expression in glomus tumors and glomuvenous malformations."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Histol Histopathol (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.14670/HH-11-782"}], "href": "https://doi.org/10.14670/HH-11-782"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27184662"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27184662"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Ioana Maria Mihai, Gheorghe-Emilian Olteanu, Diana Herman, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Analysis of Tumor Depth Invasion With Anti-Smoothelin Antibody in Equivocal Transurethral Resection of Urinary Bladder Tumor Surgical Specimens."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Int J Surg Pathol (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1177/1066896920967762"}], "href": "https://doi.org/10.1177/1066896920967762"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33090031"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33090031"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Lixin Wang, Jing Zhang, Weiguo Fu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Association of smooth muscle cell phenotypes with extracellular matrix disorders in thoracic aortic dissection."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Vasc Surg (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.jvs.2012.05.084"}], "href": "https://doi.org/10.1016/j.jvs.2012.05.084"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22960022"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22960022"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Jie Jiang, Tomohiro Nakayama, Masanori Shimodaira, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A haplotype of the SMTN gene associated with myocardial infarction in Japanese women."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Genet Test Mol Biomarkers (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1089/gtmb.2012.0034"}], "href": "https://doi.org/10.1089/gtmb.2012.0034"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22963604"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22963604"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Jie Jiang, Tomohiro Nakayama, Masanori Shimodaira, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Association of the smoothelin (SMTN) gene with cerebral infarction in men: a haplotype-based case-control study."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Vasc Med (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1177/1358863X12453938"}], "href": "https://doi.org/10.1177/1358863X12453938"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23033319"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23033319"}]}, {"type": "r", "ref": 17, "children": [{"type": "t", "text": "Jie Jiang, Tomohiro Nakayama, Masanori Shimodaira, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Haplotype of smoothelin gene associated with essential hypertension."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Hereditas (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1111/j.1601-5223.2012.02242.x"}], "href": "https://doi.org/10.1111/j.1601-5223.2012.02242.x"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23121329"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23121329"}]}, {"type": "r", "ref": 18, "children": [{"type": "t", "text": "Sébastien Lepreux, Christelle Guyot, Fabrice Billet, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Smoothelin, a new marker to determine the origin of liver fibrogenic cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "World J Gastroenterol (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3748/wjg.v19.i48.9343"}], "href": "https://doi.org/10.3748/wjg.v19.i48.9343"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24409061"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24409061"}]}]}]}
Proteins	SMTN_HUMAN
NCBI Gene ID	6525
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

SMTN has 7,688 functional associations with biological entities spanning 8 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 113 datasets.

Click the + buttons to view associations for SMTN from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

SMTN Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of SMTN gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of SMTN gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of SMTN gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of SMTN gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of SMTN gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of SMTN gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of SMTN gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of SMTN gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of SMTN gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of SMTN gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CCLE Cell Line Proteomics	Cell lines associated with SMTN protein from the CCLE Cell Line Proteomics dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with SMTN gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of SMTN gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of SMTN gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of SMTN gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of SMTN gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing SMTN protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing SMTN protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores	cellular components containing SMTN protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	cellular components containing SMTN protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with SMTN protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with SMTN protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of SMTN gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with SMTN gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Chemical Interactions	chemicals interacting with SMTN gene/protein from the curated CTD Gene-Chemical Interactions dataset.
	CTD Gene-Disease Associations	diseases associated with SMTN gene/protein from the curated CTD Gene-Disease Associations dataset.
	dbGAP Gene-Trait Associations	traits associated with SMTN gene in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.
	DeepCoverMOA Drug Mechanisms of Action	small molecule perturbations with high or low expression of SMTN protein relative to other small molecule perturbations from the DeepCoverMOA Drug Mechanisms of Action dataset.
	DepMap CRISPR Gene Dependency	cell lines with fitness changed by SMTN gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	diseases associated with SMTN gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with SMTN gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with SMTN gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with SMTN gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at SMTN gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of SMTN gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of SMTN gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing SMTN from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
	GAD Gene-Disease Associations	diseases associated with SMTN gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
	GAD High Level Gene-Disease Associations	diseases associated with SMTN gene in GWAS and other genetic association datasets from the GAD High Level Gene-Disease Associations dataset.
	GDSC Cell Line Gene Expression Profiles	cell lines with high or low expression of SMTN gene relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.