{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nThe study (PMID:"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "reports that in aging mice, increased expression of lncRNA Gm15232 in epididymal white adipose tissue acts as a competitive endogenous RNA. This upregulation sequesters miR-192-3p, relieving its inhibitory effect on the glucocorticoid receptor gene, which in turn leads to enhanced lipogenesis, a mechanism that may contribute to age‐related lipid metabolic abnormalities. Notably, the abstract does not mention SPDYE11 or provide any functional data regarding this gene. Consequently, while the study offers detailed insights into the role of lncRNA Gm15232 in lipid metabolism, it does not address the function of SPDYE11.\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Yaqi Hu, Yifan Zhang, Shuwen Wang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "LncRNA Gm15232 Promotes Lipogenesis in Aging Mice Through the miR-192-3p/GCR Pathway."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Gerontol A Biol Sci Med Sci (2024)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1093/gerona/glae066"}], "href": "https://doi.org/10.1093/gerona/glae066"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "38412501"}], "href": "https://pubmed.ncbi.nlm.nih.gov/38412501"}]}]}]}