SPDYE2 Gene

HGNC Family	Speedy/RINGO cell cycle regulator family (SPDY)
Name	speedy/RINGO cell cycle regulator family member E2
Synonyms	SPDYB2-L1, SPDYB2L1
Proteins	SPDE2_HUMAN
NCBI Gene ID	441273
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Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

SPDYE2 has 1,207 functional associations with biological entities spanning 6 categories (molecular profile, organism, functional term, phrase or reference, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 23 datasets.

Click the + buttons to view associations for SPDYE2 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome

SPDYE2 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference:

Funding

	Dataset	Summary
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of SPDYE2 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of SPDYE2 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of SPDYE2 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CHEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of SPDYE2 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	CHEA Transcription Factor Targets	transcription factors binding the promoter of SPDYE2 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with SPDYE2 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of SPDYE2 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of SPDYE2 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	gene perturbations changing expression of SPDYE2 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
	GEO Signatures of Differentially Expressed Genes for Viral Infections	virus perturbations changing expression of SPDYE2 gene from the GEO Signatures of Differentially Expressed Genes for Viral Infections dataset.
	GO Molecular Function Annotations	molecular functions performed by SPDYE2 gene from the curated GO Molecular Function Annotations dataset.
	GTEx Tissue Gene Expression Profiles	tissues with high or low expression of SPDYE2 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset.
	GTEx Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of SPDYE2 gene relative to other tissue samples from the GTEx Tissue Sample Gene Expression Profiles dataset.
	HPA Cell Line Gene Expression Profiles	cell lines with high or low expression of SPDYE2 gene relative to other cell lines from the HPA Cell Line Gene Expression Profiles dataset.
	HPA Tissue Gene Expression Profiles	tissues with high or low expression of SPDYE2 gene relative to other tissues from the HPA Tissue Gene Expression Profiles dataset.
	HPA Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of SPDYE2 gene relative to other tissue samples from the HPA Tissue Sample Gene Expression Profiles dataset.
	InterPro Predicted Protein Domain Annotations	protein domains predicted for SPDYE2 protein from the InterPro Predicted Protein Domain Annotations dataset.
	JASPAR Predicted Transcription Factor Targets	transcription factors regulating expression of SPDYE2 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.
	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	cell lines with high or low copy number of SPDYE2 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.
	TargetScan Predicted Nonconserved microRNA Targets	microRNAs regulating expression of SPDYE2 gene predicted using nonconserved miRNA seed sequences from the TargetScan Predicted Nonconserved microRNA Targets dataset.
	TCGA Signatures of Differentially Expressed Genes for Tumors	tissue samples with high or low expression of SPDYE2 gene relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.
	TISSUES Experimental Tissue Protein Expression Evidence Scores	tissues with high expression of SPDYE2 protein in proteomics datasets from the TISSUES Experimental Tissue Protein Expression Evidence Scores dataset.
	TRANSFAC Predicted Transcription Factor Targets	transcription factors regulating expression of SPDYE2 gene predicted using known transcription factor binding site motifs from the TRANSFAC Predicted Transcription Factor Targets dataset.