STK25 Gene

Name	serine/threonine kinase 25
Description	This gene encodes a member of the germinal centre kinase III (GCK III) subfamily of the sterile 20 superfamily of kinases. The encoded enzyme plays a role in serine-threonine liver kinase B1 (LKB1) signaling pathway to regulate neuronal polarization and morphology of the Golgi apparatus. The protein is translocated from the Golgi apparatus to the nucleus in response to chemical anoxia and plays a role in regulation of cell death. A pseudogene associated with this gene is located on chromosome 18. Multiple alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2012]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nSTK25 is a multifaceted serine/threonine kinase that plays key roles in cell signaling, particularly in regulating cell–cell junctions and apoptotic responses. In endothelial cells and in neural tumor models, STK25 functions downstream of cerebral cavernous malformation proteins—modulating vascular integrity and death signaling—and interacts with PDCD10 to promote oxidative stress–induced apoptosis. These studies indicate that STK25 is an important effector regulating both cell survival and death pathways in response to developmental and stress cues."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "3"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nIn addition to its signaling roles, STK25 is a critical regulator of metabolic homeostasis and tumor cell metabolism. Its functions in skeletal muscle affect metabolic gene networks"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "4"}]}, {"type": "t", "text": ", while in the liver, STK25 modulates lipid accumulation, glucose tolerance, and insulin sensitivity, contributing to hepatic steatosis. In colorectal cancer cells, it has been linked to the regulation of aerobic glycolysis, and its altered expression is observed in both prostate disease and nonalcoholic steatohepatitis-driven hepatocellular carcinoma. Moreover, STK25 influences renal lipid deposition in diabetic kidney disease and modulates high-glucose–induced injury in retinal ganglion cells, highlighting its diverse roles in metabolic and diabetic contexts."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "5", "end_ref": "11"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nSTK25 further integrates complex intracellular signaling cascades by modulating pathways that control cell proliferation, polarity, and stress responses. It has been shown to activate the Hippo pathway via promotion of LATS activation—mechanisms that are distinct from canonical hydrophobic motif phosphorylation—and to negatively regulate protein kinase A signaling by phosphorylating the regulatory subunit PRKAR1A in cardiomyocytes. Moreover, under hypoxic conditions, STK25 (also referred to as hYSK1) influences cell cycle regulators and migratory behavior, while its broader involvement in autophagy, apoptosis, and cell polarity consolidates its role as a nodal mediator in both normal physiology and tumorigenesis. Collectively, these findings underscore STK25 as a promising therapeutic target in metabolic disorders and cancers."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "12", "end_ref": "16"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Xiangjian Zheng, Chong Xu, Annarita Di Lorenzo, et al. "}, {"type": "b", "children": [{"type": "t", "text": "CCM3 signaling through sterile 20-like kinases plays an essential role during zebrafish cardiovascular development and cerebral cavernous malformations."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Clin Invest (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1172/JCI39679"}], "href": "https://doi.org/10.1172/JCI39679"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20592472"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20592472"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Heyu Zhang, Xi Ma, Xuan Deng, et al. "}, {"type": "b", "children": [{"type": "t", "text": "PDCD10 interacts with STK25 to accelerate cell apoptosis under oxidative stress."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Front Biosci (Landmark Ed) (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.2741/4053"}], "href": "https://doi.org/10.2741/4053"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22652780"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22652780"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Barbara Costa, Michelle J Kean, Volker Ast, et al. "}, {"type": "b", "children": [{"type": "t", "text": "STK25 protein mediates TrkA and CCM2 protein-dependent death in pediatric tumor cells of neural origin."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.C112.345397"}], "href": "https://doi.org/10.1074/jbc.C112.345397"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22782892"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22782892"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "A Nerstedt, E Cansby, C X Andersson, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Serine/threonine protein kinase 25 (STK25): a novel negative regulator of lipid and glucose metabolism in rodent and human skeletal muscle."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Diabetologia (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s00125-012-2511-7"}], "href": "https://doi.org/10.1007/s00125-012-2511-7"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22391949"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22391949"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Heyu Zhang, Xi Ma, Saihui Peng, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Differential expression of MST4, STK25 and PDCD10 between benign prostatic hyperplasia and prostate cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Int J Clin Exp Pathol (2014)"}]}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25550858"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25550858"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Manoj Amrutkar, Matthias Kern, Esther Nuñez-Durán, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Protein kinase STK25 controls lipid partitioning in hepatocytes and correlates with liver fat content in humans."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Diabetologia (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s00125-015-3801-7"}], "href": "https://doi.org/10.1007/s00125-015-3801-7"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26553096"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26553096"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Fan Wu, Pin Gao, Wei Wu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "STK25-induced inhibition of aerobic glycolysis via GOLPH3-mTOR pathway suppresses cell proliferation in colorectal cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Exp Clin Cancer Res (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/s13046-018-0808-1"}], "href": "https://doi.org/10.1186/s13046-018-0808-1"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29996891"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29996891"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Emmelie Cansby, Mara Caputo, Lei Gao, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Depletion of protein kinase STK25 ameliorates renal lipotoxicity and protects against diabetic kidney disease."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "JCI Insight (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1172/jci.insight.140483"}], "href": "https://doi.org/10.1172/jci.insight.140483"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33170807"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33170807"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Yeshwant Kurhe, Mara Caputo, Emmelie Cansby, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Antagonizing STK25 Signaling Suppresses the Development of Hepatocellular Carcinoma Through Targeting Metabolic, Inflammatory, and Pro-Oncogenic Pathways."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Mol Gastroenterol Hepatol (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.jcmgh.2021.09.018"}], "href": "https://doi.org/10.1016/j.jcmgh.2021.09.018"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34624527"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34624527"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Zhuolin Zhou, Haiyan Li, Shuwei Bai, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Loss of serine/threonine protein kinase 25 in retinal ganglion cells ameliorates high glucose-elicited damage through regulation of the AKT-GSK-3β/Nrf2 pathway."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem Biophys Res Commun (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.bbrc.2022.02.044"}], "href": "https://doi.org/10.1016/j.bbrc.2022.02.044"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "35217361"}], "href": "https://pubmed.ncbi.nlm.nih.gov/35217361"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Jiangbo Chen, Pin Gao, Lin Peng, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Downregulation of STK25 promotes autophagy via the Janus kinase 2/signal transducer and activator of transcription 3 pathway in colorectal cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Carcinog (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/mc.23403"}], "href": "https://doi.org/10.1002/mc.23403"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "35349179"}], "href": "https://pubmed.ncbi.nlm.nih.gov/35349179"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Mee-Hyun Lee, Joydeb Kumar Kundu, Bu Young Choi "}, {"type": "b", "children": [{"type": "t", "text": "p21"}, {"type": "a", "children": [{"type": "t", "text": "sup"}], "href": "sup"}, {"type": "t", "text": "WAF1/Cip1"}, {"type": "a", "children": [{"type": "t", "text": "/sup"}], "href": "/sup"}, {"type": "t", "text": " Regulation by hYSK1 Activates SP-1 Transcription Factor and Increases MMP-2 Expression under Hypoxic Conditions."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Int J Mol Sci (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3390/ijms20020310"}], "href": "https://doi.org/10.3390/ijms20020310"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30646538"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30646538"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Sanghee Lim, Nicole Hermance, Tenny Mudianto, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Identification of the kinase STK25 as an upstream activator of LATS signaling."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Commun (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41467-019-09597-w"}], "href": "https://doi.org/10.1038/s41467-019-09597-w"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30948712"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30948712"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Sung Jun Bae, Lisheng Ni, Xuelian Luo "}, {"type": "b", "children": [{"type": "t", "text": "STK25 suppresses Hippo signaling by regulating SAV1-STRIPAK antagonism."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Elife (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.7554/eLife.54863"}], "href": "https://doi.org/10.7554/eLife.54863"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32292165"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32292165"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Xiaokan Zhang, Bryan Z Wang, Michael Kim, et al. "}, {"type": "b", "children": [{"type": "t", "text": "STK25 inhibits PKA signaling by phosphorylating PRKAR1A."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Rep (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.celrep.2022.111203"}], "href": "https://doi.org/10.1016/j.celrep.2022.111203"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "35977512"}], "href": "https://pubmed.ncbi.nlm.nih.gov/35977512"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Ke-Qian Chen, Guan-Lan Lei, Bo-Yi Ke, et al. "}, {"type": "b", "children": [{"type": "t", "text": "STK25: a viable therapeutic target for cancer treatments?"}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Anticancer Drugs (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1097/CAD.0000000000001490"}], "href": "https://doi.org/10.1097/CAD.0000000000001490"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "36728989"}], "href": "https://pubmed.ncbi.nlm.nih.gov/36728989"}]}]}]}
Synonyms	SOK1, YSK1
Proteins	STK25_HUMAN
NCBI Gene ID	10494
API
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Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

STK25 has 7,893 functional associations with biological entities spanning 9 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 112 datasets.

Click the + buttons to view associations for STK25 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

STK25 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of STK25 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of STK25 gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of STK25 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of STK25 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of STK25 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of STK25 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of STK25 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of STK25 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of STK25 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	small molecule perturbations changing expression of STK25 gene from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of STK25 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of STK25 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CCLE Cell Line Gene Mutation Profiles	cell lines with STK25 gene mutations from the CCLE Cell Line Gene Mutation Profiles dataset.
	CCLE Cell Line Proteomics	Cell lines associated with STK25 protein from the CCLE Cell Line Proteomics dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with STK25 gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of STK25 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of STK25 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of STK25 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	gene perturbations changing expression of STK25 gene from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of STK25 gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing STK25 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing STK25 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with STK25 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with STK25 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with STK25 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Chemical Interactions	chemicals interacting with STK25 gene/protein from the curated CTD Gene-Chemical Interactions dataset.
	CTD Gene-Disease Associations	diseases associated with STK25 gene/protein from the curated CTD Gene-Disease Associations dataset.
	DeepCoverMOA Drug Mechanisms of Action	small molecule perturbations with high or low expression of STK25 protein relative to other small molecule perturbations from the DeepCoverMOA Drug Mechanisms of Action dataset.
	DepMap CRISPR Gene Dependency	cell lines with fitness changed by STK25 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	diseases associated with STK25 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with STK25 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with STK25 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with STK25 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with STK25 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at STK25 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of STK25 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of STK25 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing STK25 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
	GDSC Cell Line Gene Expression Profiles	cell lines with high or low expression of STK25 gene relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.
	GeneRIF Biological Term Annotations	biological terms co-occuring with STK25 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.