{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nThe study in reference (1) examines how mutations in the Golgi SNARE protein Membrin (encoded by the GOSR2 gene) lead to partial reductions in SNARE-mediated ER-to-Golgi membrane fusion, ultimately impairing dendritic growth and destabilizing synaptic function in neuronal models. Despite its detailed exploration of secretory pathway deficits leading to progressive myoclonus epilepsy, the abstract does not provide any information on the function of STPG3. As such, within the context of the cited work, the biological role of STPG3 remains unaddressed and requires further investigation."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": ""}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Roman Praschberger, Simon A Lowe, Nancy T Malintan, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Mutations in Membrin/GOSR2 Reveal Stringent Secretory Pathway Demands of Dendritic Growth and Synaptic Integrity."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Rep (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.celrep.2017.09.004"}], "href": "https://doi.org/10.1016/j.celrep.2017.09.004"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28978487"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28978487"}]}]}]}