HGNC Family | ATP binding cassette transporters (ABC) |
Name | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
Description | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014] |
Summary |
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nA careful review of the provided abstracts reveals that they predominantly focus on the endocannabinoid system—its receptors (particularly CB1 and CB2) and their roles in regulating synaptic transmission, energy balance, neural plasticity, inflammation, and other physiological processes. None of these abstracts, however, make any mention of TAP1 (the transporter associated with antigen processing 1) or discuss its function in antigen presentation, immune regulation, or related pathways. As such, while these studies offer deep insights into cannabinoid signaling in various contexts, they do not address TAP1."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "33"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nIn summary, while the collection of studies cited above provides a comprehensive view of cannabinoid receptor–mediated functions in the nervous system, metabolism, immunity, and beyond, they do not offer any insights into the function of TAP1. Therefore, no summary of TAP1’s role can be drawn from these abstracts; researchers interested in TAP1 will need to refer to literature specifically addressing its involvement in antigen processing and immune regulation."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "33"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "H Hermann, G Marsicano, B Lutz "}, {"type": "b", "children": [{"type": "t", "text": "Coexpression of the cannabinoid receptor type 1 with dopamine and serotonin receptors in distinct neuronal subpopulations of the adult mouse forebrain."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Neuroscience (2002)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/s0306-4522(01)00509-7"}], "href": "https://doi.org/10.1016/s0306-4522(01"}, {"type": "t", "text": "00509-7) PMID: "}, {"type": "a", "children": [{"type": "t", "text": "11823058"}], "href": "https://pubmed.ncbi.nlm.nih.gov/11823058"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Miquel Martin, Catherine Ledent, Marc Parmentier, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Involvement of CB1 cannabinoid receptors in emotional behaviour."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Psychopharmacology (Berl) (2002)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s00213-001-0946-5"}], "href": "https://doi.org/10.1007/s00213-001-0946-5"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "11823890"}], "href": "https://pubmed.ncbi.nlm.nih.gov/11823890"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Giovanni Marsicano, Bemd Moosmann, Heike Hermann, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Neuroprotective properties of cannabinoids against oxidative stress: role of the cannabinoid receptor CB1."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Neurochem (2002)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1046/j.0022-3042.2001.00716.x"}], "href": "https://doi.org/10.1046/j.0022-3042.2001.00716.x"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "11905991"}], "href": "https://pubmed.ncbi.nlm.nih.gov/11905991"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Giovanni Marsicano, Carsten T Wotjak, Shahnaz C Azad, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The endogenous cannabinoid system controls extinction of aversive memories."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nature (2002)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/nature00839"}], "href": "https://doi.org/10.1038/nature00839"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12152079"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12152079"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Christine Ravinet Trillou, Michele Arnone, Claire Delgorge, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Anti-obesity effect of SR141716, a CB1 receptor antagonist, in diet-induced obese mice."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Am J Physiol Regul Integr Comp Physiol (2003)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1152/ajpregu.00545.2002"}], "href": "https://doi.org/10.1152/ajpregu.00545.2002"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12399252"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12399252"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "M Llanos Casanova, Cristina Blázquez, Jesús Martínez-Palacio, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Clin Invest (2003)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1172/JCI16116"}], "href": "https://doi.org/10.1172/JCI16116"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12511587"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12511587"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Lei Wang, Jie Liu, Judith Harvey-White, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Endocannabinoid signaling via cannabinoid receptor 1 is involved in ethanol preference and its age-dependent decline in mice."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Proc Natl Acad Sci U S A (2003)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1073/pnas.0336351100"}], "href": "https://doi.org/10.1073/pnas.0336351100"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12538878"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12538878"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Basalingappa L Hungund, Istvan Szakall, Agota Adam, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Cannabinoid CB1 receptor knockout mice exhibit markedly reduced voluntary alcohol consumption and lack alcohol-induced dopamine release in the nucleus accumbens."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Neurochem (2003)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1046/j.1471-4159.2003.01576.x"}], "href": "https://doi.org/10.1046/j.1471-4159.2003.01576.x"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12562514"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12562514"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Daniela Cota, Giovanni Marsicano, Matthias Tschöp, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Clin Invest (2003)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1172/JCI17725"}], "href": "https://doi.org/10.1172/JCI17725"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12897210"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12897210"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Giovanni Marsicano, Sharon Goodenough, Krisztina Monory, et al. "}, {"type": "b", "children": [{"type": "t", "text": "CB1 cannabinoid receptors and on-demand defense against excitotoxicity."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Science (2003)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1126/science.1088208"}], "href": "https://doi.org/10.1126/science.1088208"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "14526074"}], "href": "https://pubmed.ncbi.nlm.nih.gov/14526074"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Toshihiko Toyofuku, Hong Zhang, Atsushi Kumanogoh, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Dual roles of Sema6D in cardiac morphogenesis through region-specific association of its receptor, Plexin-A1, with off-track and vascular endothelial growth factor receptor type 2."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Genes Dev (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1101/gad.1167304"}], "href": "https://doi.org/10.1101/gad.1167304"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "14977921"}], "href": "https://pubmed.ncbi.nlm.nih.gov/14977921"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "J Haller, B Varga, C Ledent, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Context-dependent effects of CB1 cannabinoid gene disruption on anxiety-like and social behaviour in mice."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Eur J Neurosci (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1111/j.1460-9568.2004.03293.x"}], "href": "https://doi.org/10.1111/j.1460-9568.2004.03293.x"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15078564"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15078564"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Hakim Houchi, Daniela Babovic, Olivier Pierrefiche, et al. "}, {"type": "b", "children": [{"type": "t", "text": "CB1 receptor knockout mice display reduced ethanol-induced conditioned place preference and increased striatal dopamine D2 receptors."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Neuropsychopharmacology (2005)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/sj.npp.1300568"}], "href": "https://doi.org/10.1038/sj.npp.1300568"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15383833"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15383833"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Douglas Osei-Hyiaman, Michael DePetrillo, Pál Pacher, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Clin Invest (2005)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1172/JCI23057"}], "href": "https://doi.org/10.1172/JCI23057"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15864349"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15864349"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Aymen I Idris, Robert J van 't Hof, Iain R Greig, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Regulation of bone mass, bone loss and osteoclast activity by cannabinoid receptors."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Med (2005)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/nm1255"}], "href": "https://doi.org/10.1038/nm1255"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15908955"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15908955"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "L Cristino, L de Petrocellis, G Pryce, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Immunohistochemical localization of cannabinoid type 1 and vanilloid transient receptor potential vanilloid type 1 receptors in the mouse brain."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Neuroscience (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.neuroscience.2006.02.074"}], "href": "https://doi.org/10.1016/j.neuroscience.2006.02.074"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16603318"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16603318"}]}, {"type": "r", "ref": 17, "children": [{"type": "t", "text": "Fatima Teixeira-Clerc, Boris Julien, Pascale Grenard, et al. "}, {"type": "b", "children": [{"type": "t", "text": "CB1 cannabinoid receptor antagonism: a new strategy for the treatment of liver fibrosis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Med (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/nm1421"}], "href": "https://doi.org/10.1038/nm1421"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16715087"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16715087"}]}, {"type": "r", "ref": 18, "children": [{"type": "t", "text": "Cristina Blázquez, Arkaitz Carracedo, Lucía Barrado, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Cannabinoid receptors as novel targets for the treatment of melanoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "FASEB J (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1096/fj.06-6638fje"}], "href": "https://doi.org/10.1096/fj.06-6638fje"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17065222"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17065222"}]}, {"type": "r", "ref": 19, "children": [{"type": "t", "text": "Katarzyna Maresz, Gareth Pryce, Eugene D Ponomarev, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Direct suppression of CNS autoimmune inflammation via the cannabinoid receptor CB1 on neurons and CB2 on autoreactive T cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Med (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/nm1561"}], "href": "https://doi.org/10.1038/nm1561"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17401376"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17401376"}]}, {"type": "r", "ref": 20, "children": [{"type": "t", "text": "Vivien Chevaleyre, Boris D Heifets, Pascal S Kaeser, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Endocannabinoid-mediated long-term plasticity requires cAMP/PKA signaling and RIM1alpha."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Neuron (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.neuron.2007.05.020"}], "href": "https://doi.org/10.1016/j.neuron.2007.05.020"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17553427"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17553427"}]}, {"type": "r", "ref": 21, "children": [{"type": "t", "text": "Meliha Karsak, Evelyn Gaffal, Rahul Date, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Attenuation of allergic contact dermatitis through the endocannabinoid system."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Science (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1126/science.1142265"}], "href": "https://doi.org/10.1126/science.1142265"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17556587"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17556587"}]}, {"type": "r", "ref": 22, "children": [{"type": "t", "text": "Joseph Tam, Victoria Trembovler, Vincenzo Di Marzo, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The cannabinoid CB1 receptor regulates bone formation by modulating adrenergic signaling."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "FASEB J (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1096/fj.06-7957com"}], "href": "https://doi.org/10.1096/fj.06-7957com"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17704191"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17704191"}]}, {"type": "r", "ref": 23, "children": [{"type": "t", "text": "Won-il Jeong, Douglas Osei-Hyiaman, Ogyi Park, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Paracrine activation of hepatic CB1 receptors by stellate cell-derived endocannabinoids mediates alcoholic fatty liver."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Metab (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.cmet.2007.12.007"}], "href": "https://doi.org/10.1016/j.cmet.2007.12.007"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18316028"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18316028"}]}, {"type": "r", "ref": 24, "children": [{"type": "t", "text": "Douglas Osei-Hyiaman, Jie Liu, Liang Zhou, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Hepatic CB1 receptor is required for development of diet-induced steatosis, dyslipidemia, and insulin and leptin resistance in mice."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Clin Invest (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1172/JCI34827"}], "href": "https://doi.org/10.1172/JCI34827"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18677409"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18677409"}]}, {"type": "r", "ref": 25, "children": [{"type": "t", "text": "Alejandro J Pernía-Andrade, Ako Kato, Robert Witschi, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Spinal endocannabinoids and CB1 receptors mediate C-fiber-induced heterosynaptic pain sensitization."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Science (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1126/science.1171870"}], "href": "https://doi.org/10.1126/science.1171870"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19661434"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19661434"}]}, {"type": "r", "ref": 26, "children": [{"type": "t", "text": "Ryusuke Yoshida, Tadahiro Ohkuri, Masafumi Jyotaki, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Endocannabinoids selectively enhance sweet taste."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Proc Natl Acad Sci U S A (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1073/pnas.0912048107"}], "href": "https://doi.org/10.1073/pnas.0912048107"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20080779"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20080779"}]}, {"type": "r", "ref": 27, "children": [{"type": "t", "text": "Carmelo Quarta, Luigi Bellocchio, Giacomo Mancini, et al. "}, {"type": "b", "children": [{"type": "t", "text": "CB(1) signaling in forebrain and sympathetic neurons is a key determinant of endocannabinoid actions on energy balance."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Metab (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.cmet.2010.02.015"}], "href": "https://doi.org/10.1016/j.cmet.2010.02.015"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20374960"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20374960"}]}, {"type": "r", "ref": 28, "children": [{"type": "t", "text": "Jie Liu, Liang Zhou, Keming Xiong, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Hepatic cannabinoid receptor-1 mediates diet-induced insulin resistance via inhibition of insulin signaling and clearance in mice."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Gastroenterology (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1053/j.gastro.2012.01.032"}], "href": "https://doi.org/10.1053/j.gastro.2012.01.032"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22307032"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22307032"}]}, {"type": "r", "ref": 29, "children": [{"type": "t", "text": "Mohanraj Rajesh, Sándor Bátkai, Malek Kechrid, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Cannabinoid 1 receptor promotes cardiac dysfunction, oxidative stress, inflammation, and fibrosis in diabetic cardiomyopathy."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Diabetes (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.2337/db11-0477"}], "href": "https://doi.org/10.2337/db11-0477"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22315315"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22315315"}]}, {"type": "r", "ref": 30, "children": [{"type": "t", "text": "Giovanni Bénard, Federico Massa, Nagore Puente, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Mitochondrial CB₁ receptors regulate neuronal energy metabolism."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Neurosci (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/nn.3053"}], "href": "https://doi.org/10.1038/nn.3053"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22388959"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22388959"}]}, {"type": "r", "ref": 31, "children": [{"type": "t", "text": "Joseph Tam, Resat Cinar, Jie Liu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Peripheral cannabinoid-1 receptor inverse agonism reduces obesity by reversing leptin resistance."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Metab (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.cmet.2012.07.002"}], "href": "https://doi.org/10.1016/j.cmet.2012.07.002"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22841573"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22841573"}]}, {"type": "r", "ref": 32, "children": [{"type": "t", "text": "Arnau Busquets-Garcia, Maria Gomis-González, Thomas Guegan, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Targeting the endocannabinoid system in the treatment of fragile X syndrome."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Med (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/nm.3127"}], "href": "https://doi.org/10.1038/nm.3127"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23542787"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23542787"}]}, {"type": "r", "ref": 33, "children": [{"type": "t", "text": "Laurie M Robin, José F Oliveira da Cruz, Valentin C Langlais, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Astroglial CB"}, {"type": "a", "children": [{"type": "t", "text": "sub"}], "href": "sub"}, {"type": "t", "text": "1"}, {"type": "a", "children": [{"type": "t", "text": "/sub"}], "href": "/sub"}, {"type": "t", "text": " Receptors Determine Synaptic D-Serine Availability to Enable Recognition Memory."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Neuron (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.neuron.2018.04.034"}], "href": "https://doi.org/10.1016/j.neuron.2018.04.034"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29779943"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29779943"}]}]}]}
|
Synonyms | PSF-1, ABC17, ABCB2, PSF1, TAP1*0102N, D6S114E, TAP1N, RING4 |
Proteins | TAP1_HUMAN |
NCBI Gene ID | 6890 |
API | |
Download Associations | |
Predicted Functions |
![]() |
Co-expressed Genes |
![]() |
Expression in Tissues and Cell Lines |
![]() |
TAP1 has 8,613 functional associations with biological entities spanning 8 categories (molecular profile, organism, functional term, phrase or reference, chemical, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 111 datasets.
Click the + buttons to view associations for TAP1 from the datasets below.
If available, associations are ranked by standardized value
Dataset | Summary | |
---|---|---|
Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles | tissues with high or low expression of TAP1 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset. | |
Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles | tissues with high or low expression of TAP1 gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset. | |
Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray | tissue samples with high or low expression of TAP1 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset. | |
Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq | tissue samples with high or low expression of TAP1 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset. | |
Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles | tissues with high or low expression of TAP1 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset. | |
Biocarta Pathways | pathways involving TAP1 protein from the Biocarta Pathways dataset. | |
BioGPS Cell Line Gene Expression Profiles | cell lines with high or low expression of TAP1 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset. | |
BioGPS Human Cell Type and Tissue Gene Expression Profiles | cell types and tissues with high or low expression of TAP1 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset. | |
BioGPS Mouse Cell Type and Tissue Gene Expression Profiles | cell types and tissues with high or low expression of TAP1 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset. | |
CCLE Cell Line Gene CNV Profiles | cell lines with high or low copy number of TAP1 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset. | |
CCLE Cell Line Gene Expression Profiles | cell lines with high or low expression of TAP1 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset. | |
CCLE Cell Line Proteomics | Cell lines associated with TAP1 protein from the CCLE Cell Line Proteomics dataset. | |
CellMarker Gene-Cell Type Associations | cell types associated with TAP1 gene from the CellMarker Gene-Cell Type Associations dataset. | |
ChEA Transcription Factor Binding Site Profiles | transcription factor binding site profiles with transcription factor binding evidence at the promoter of TAP1 gene from the CHEA Transcription Factor Binding Site Profiles dataset. | |
ChEA Transcription Factor Targets | transcription factors binding the promoter of TAP1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset. | |
ChEA Transcription Factor Targets 2022 | transcription factors binding the promoter of TAP1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset. | |
CMAP Signatures of Differentially Expressed Genes for Small Molecules | small molecule perturbations changing expression of TAP1 gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset. | |
COMPARTMENTS Curated Protein Localization Evidence Scores | cellular components containing TAP1 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset. | |
COMPARTMENTS Text-mining Protein Localization Evidence Scores | cellular components co-occuring with TAP1 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset. | |
COSMIC Cell Line Gene CNV Profiles | cell lines with high or low copy number of TAP1 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset. | |
COSMIC Cell Line Gene Mutation Profiles | cell lines with TAP1 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset. | |
CTD Gene-Chemical Interactions | chemicals interacting with TAP1 gene/protein from the curated CTD Gene-Chemical Interactions dataset. | |
CTD Gene-Disease Associations | diseases associated with TAP1 gene/protein from the curated CTD Gene-Disease Associations dataset. | |
dbGAP Gene-Trait Associations | traits associated with TAP1 gene in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset. | |
DeepCoverMOA Drug Mechanisms of Action | small molecule perturbations with high or low expression of TAP1 protein relative to other small molecule perturbations from the DeepCoverMOA Drug Mechanisms of Action dataset. | |
DepMap CRISPR Gene Dependency | cell lines with fitness changed by TAP1 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset. | |
DISEASES Curated Gene-Disease Association Evidence Scores 2025 | diseases involving TAP1 gene from the DISEASES Curated Gene-Disease Association Evidence Scores 2025 dataset. | |
DISEASES Experimental Gene-Disease Association Evidence Scores | diseases associated with TAP1 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset. | |
DISEASES Experimental Gene-Disease Association Evidence Scores 2025 | diseases associated with TAP1 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset. | |
DISEASES Text-mining Gene-Disease Association Evidence Scores | diseases co-occuring with TAP1 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset. | |
DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 | diseases co-occuring with TAP1 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset. | |
DisGeNET Gene-Disease Associations | diseases associated with TAP1 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset. | |
DisGeNET Gene-Phenotype Associations | phenotypes associated with TAP1 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset. | |
DrugBank Drug Targets | interacting drugs for TAP1 protein from the curated DrugBank Drug Targets dataset. | |
ENCODE Histone Modification Site Profiles | histone modification site profiles with high histone modification abundance at TAP1 gene from the ENCODE Histone Modification Site Profiles dataset. | |
ENCODE Transcription Factor Binding Site Profiles | transcription factor binding site profiles with transcription factor binding evidence at the promoter of TAP1 gene from the ENCODE Transcription Factor Binding Site Profiles dataset. | |
ENCODE Transcription Factor Targets | transcription factors binding the promoter of TAP1 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset. | |
ESCAPE Omics Signatures of Genes and Proteins for Stem Cells | PubMedIDs of publications reporting gene signatures containing TAP1 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset. | |
GAD Gene-Disease Associations | diseases associated with TAP1 gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset. | |
GAD High Level Gene-Disease Associations | diseases associated with TAP1 gene in GWAS and other genetic association datasets from the GAD High Level Gene-Disease Associations dataset. | |
GDSC Cell Line Gene Expression Profiles | cell lines with high or low expression of TAP1 gene relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset. | |
GeneRIF Biological Term Annotations | biological terms co-occuring with TAP1 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. | |
GeneSigDB Published Gene Signatures | PubMedIDs of publications reporting gene signatures containing TAP1 from the GeneSigDB Published Gene Signatures dataset. | |
GEO Signatures of Differentially Expressed Genes for Diseases | disease perturbations changing expression of TAP1 gene from the GEO Signatures of Differentially Expressed Genes for Diseases dataset. | |
GEO Signatures of Differentially Expressed Genes for Gene Perturbations | gene perturbations changing expression of TAP1 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset. | |
GEO Signatures of Differentially Expressed Genes for Kinase Perturbations | kinase perturbations changing expression of TAP1 gene from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset. | |
GEO Signatures of Differentially Expressed Genes for Small Molecules | small molecule perturbations changing expression of TAP1 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset. | |
GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations | transcription factor perturbations changing expression of TAP1 gene from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset. | |
GEO Signatures of Differentially Expressed Genes for Viral Infections | virus perturbations changing expression of TAP1 gene from the GEO Signatures of Differentially Expressed Genes for Viral Infections dataset. | |
GO Biological Process Annotations 2015 | biological processes involving TAP1 gene from the curated GO Biological Process Annotations 2015 dataset. | |
GO Biological Process Annotations 2023 | biological processes involving TAP1 gene from the curated GO Biological Process Annotations 2023 dataset. | |
GO Cellular Component Annotations 2015 | cellular components containing TAP1 protein from the curated GO Cellular Component Annotations 2015 dataset. | |
GO Cellular Component Annotations 2023 | cellular components containing TAP1 protein from the curated GO Cellular Component Annotations 2023 dataset. | |
GO Molecular Function Annotations 2015 | molecular functions performed by TAP1 gene from the curated GO Molecular Function Annotations 2015 dataset. | |
GO Molecular Function Annotations 2023 | molecular functions performed by TAP1 gene from the curated GO Molecular Function Annotations 2023 dataset. | |
GTEx Tissue Gene Expression Profiles | tissues with high or low expression of TAP1 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset. | |
GTEx Tissue Gene Expression Profiles 2023 | tissues with high or low expression of TAP1 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles 2023 dataset. | |
GTEx Tissue Sample Gene Expression Profiles | tissue samples with high or low expression of TAP1 gene relative to other tissue samples from the GTEx Tissue Sample Gene Expression Profiles dataset. | |
GWASdb SNP-Disease Associations | diseases associated with TAP1 gene in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset. | |
GWASdb SNP-Phenotype Associations | phenotypes associated with TAP1 gene in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset. | |
HMDB Metabolites of Enzymes | interacting metabolites for TAP1 protein from the curated HMDB Metabolites of Enzymes dataset. | |
HPA Cell Line Gene Expression Profiles | cell lines with high or low expression of TAP1 gene relative to other cell lines from the HPA Cell Line Gene Expression Profiles dataset. | |
HPA Tissue Gene Expression Profiles | tissues with high or low expression of TAP1 gene relative to other tissues from the HPA Tissue Gene Expression Profiles dataset. | |
HPA Tissue Sample Gene Expression Profiles | tissue samples with high or low expression of TAP1 gene relative to other tissue samples from the HPA Tissue Sample Gene Expression Profiles dataset. | |
HPM Cell Type and Tissue Protein Expression Profiles | cell types and tissues with high or low expression of TAP1 protein relative to other cell types and tissues from the HPM Cell Type and Tissue Protein Expression Profiles dataset. | |
HPO Gene-Disease Associations | phenotypes associated with TAP1 gene by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset. | |
Hub Proteins Protein-Protein Interactions | interacting hub proteins for TAP1 from the curated Hub Proteins Protein-Protein Interactions dataset. | |
HuGE Navigator Gene-Phenotype Associations | phenotypes associated with TAP1 gene by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset. | |
IMPC Knockout Mouse Phenotypes | phenotypes of mice caused by TAP1 gene knockout from the IMPC Knockout Mouse Phenotypes dataset. | |
InterPro Predicted Protein Domain Annotations | protein domains predicted for TAP1 protein from the InterPro Predicted Protein Domain Annotations dataset. | |
JASPAR Predicted Transcription Factor Targets | transcription factors regulating expression of TAP1 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset. | |
KEGG Pathways | pathways involving TAP1 protein from the KEGG Pathways dataset. | |
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles | cell lines with high or low copy number of TAP1 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset. | |
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles | cell lines with high or low expression of TAP1 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles dataset. | |
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles | cell lines with TAP1 gene mutations from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset. | |
KnockTF Gene Expression Profiles with Transcription Factor Perturbations | transcription factor perturbations changing expression of TAP1 gene from the KnockTF Gene Expression Profiles with Transcription Factor Perturbations dataset. | |
LINCS L1000 CMAP Chemical Perturbation Consensus Signatures | small molecule perturbations changing expression of TAP1 gene from the LINCS L1000 CMAP Chemical Perturbations Consensus Signatures dataset. | |
LINCS L1000 CMAP CRISPR Knockout Consensus Signatures | gene perturbations changing expression of TAP1 gene from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset. | |
LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules | small molecule perturbations changing expression of TAP1 gene from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset. | |
LOCATE Curated Protein Localization Annotations | cellular components containing TAP1 protein in low- or high-throughput protein localization assays from the LOCATE Curated Protein Localization Annotations dataset. | |
LOCATE Predicted Protein Localization Annotations | cellular components predicted to contain TAP1 protein from the LOCATE Predicted Protein Localization Annotations dataset. | |
MGI Mouse Phenotype Associations 2023 | phenotypes of transgenic mice caused by TAP1 gene mutations from the MGI Mouse Phenotype Associations 2023 dataset. | |
MiRTarBase microRNA Targets | microRNAs targeting TAP1 gene in low- or high-throughput microRNA targeting studies from the MiRTarBase microRNA Targets dataset. | |
MotifMap Predicted Transcription Factor Targets | transcription factors regulating expression of TAP1 gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset. | |
MoTrPAC Rat Endurance Exercise Training | tissue samples with high or low expression of TAP1 gene relative to other tissue samples from the MoTrPAC Rat Endurance Exercise Training dataset. | |
MPO Gene-Phenotype Associations | phenotypes of transgenic mice caused by TAP1 gene mutations from the MPO Gene-Phenotype Associations dataset. | |
MSigDB Cancer Gene Co-expression Modules | co-expressed genes for TAP1 from the MSigDB Cancer Gene Co-expression Modules dataset. | |
MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations | gene perturbations changing expression of TAP1 gene from the MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations dataset. | |
NURSA Protein Complexes | protein complexs containing TAP1 protein recovered by IP-MS from the NURSA Protein Complexes dataset. | |
OMIM Gene-Disease Associations | phenotypes associated with TAP1 gene from the curated OMIM Gene-Disease Associations dataset. | |
Pathway Commons Protein-Protein Interactions | interacting proteins for TAP1 from the Pathway Commons Protein-Protein Interactions dataset. | |
PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations | gene perturbations changing expression of TAP1 gene from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset. | |
PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations | gene perturbations changing expression of TAP1 gene from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset. | |
PFOCR Pathway Figure Associations 2023 | pathways involving TAP1 protein from the PFOCR Pathway Figure Associations 2023 dataset. | |
PFOCR Pathway Figure Associations 2024 | pathways involving TAP1 protein from the Wikipathways PFOCR 2024 dataset. | |
PID Pathways | pathways involving TAP1 protein from the PID Pathways dataset. | |
Reactome Pathways 2014 | pathways involving TAP1 protein from the Reactome Pathways dataset. | |
Reactome Pathways 2024 | pathways involving TAP1 protein from the Reactome Pathways 2024 dataset. | |
Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles | cell types and tissues with high or low DNA methylation of TAP1 gene relative to other cell types and tissues from the Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles dataset. | |
Roadmap Epigenomics Cell and Tissue Gene Expression Profiles | cell types and tissues with high or low expression of TAP1 gene relative to other cell types and tissues from the Roadmap Epigenomics Cell and Tissue Gene Expression Profiles dataset. | |
RummaGEO Drug Perturbation Signatures | drug perturbations changing expression of TAP1 gene from the RummaGEO Drug Perturbation Signatures dataset. | |
RummaGEO Gene Perturbation Signatures | gene perturbations changing expression of TAP1 gene from the RummaGEO Gene Perturbation Signatures dataset. | |
Sanger Dependency Map Cancer Cell Line Proteomics | cell lines associated with TAP1 protein from the Sanger Dependency Map Cancer Cell Line Proteomics dataset. | |
TargetScan Predicted Conserved microRNA Targets | microRNAs regulating expression of TAP1 gene predicted using conserved miRNA seed sequences from the TargetScan Predicted Conserved microRNA Targets dataset. | |
TargetScan Predicted Nonconserved microRNA Targets | microRNAs regulating expression of TAP1 gene predicted using nonconserved miRNA seed sequences from the TargetScan Predicted Nonconserved microRNA Targets dataset. | |
TCGA Signatures of Differentially Expressed Genes for Tumors | tissue samples with high or low expression of TAP1 gene relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset. | |
TISSUES Curated Tissue Protein Expression Evidence Scores | tissues with high expression of TAP1 protein from the TISSUES Curated Tissue Protein Expression Evidence Scores dataset. | |
TISSUES Experimental Tissue Protein Expression Evidence Scores | tissues with high expression of TAP1 protein in proteomics datasets from the TISSUES Experimental Tissue Protein Expression Evidence Scores dataset. | |
TISSUES Text-mining Tissue Protein Expression Evidence Scores | tissues co-occuring with TAP1 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset. | |
WikiPathways Pathways 2014 | pathways involving TAP1 protein from the Wikipathways Pathways 2014 dataset. | |
WikiPathways Pathways 2024 | pathways involving TAP1 protein from the WikiPathways Pathways 2024 dataset. | |