TRBC1 Gene

HGNC Family	T cell receptors (TR)
Name	T cell receptor beta constant 1
Synonyms	BV05S1J2.2, TCRBC1
Proteins	TRBC1_HUMAN
NCBI Gene ID	28639
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Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

TRBC1 has 1,223 functional associations with biological entities spanning 5 categories (chemical, functional term, phrase or reference, disease, phenotype or trait, cell line, cell type or tissue, gene, protein or microRNA) extracted from 24 datasets.

Click the + buttons to view associations for TRBC1 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

TRBC1 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference:

	Dataset	Summary
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of TRBC1 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of TRBC1 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with TRBC1 gene from the CellMarker Gene-Cell Type Associations dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of TRBC1 gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing TRBC1 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with TRBC1 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	CTD Gene-Disease Associations	diseases associated with TRBC1 gene/protein from the curated CTD Gene-Disease Associations dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores	diseases associated with TRBC1 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with TRBC1 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DrugBank Drug Targets	interacting drugs for TRBC1 protein from the curated DrugBank Drug Targets dataset.
	GeneSigDB Published Gene Signatures	PubMedIDs of publications reporting gene signatures containing TRBC1 from the GeneSigDB Published Gene Signatures dataset.
	GEO Signatures of Differentially Expressed Genes for Diseases	disease perturbations changing expression of TRBC1 gene from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.
	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	gene perturbations changing expression of TRBC1 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
	GEO Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of TRBC1 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset.
	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	transcription factor perturbations changing expression of TRBC1 gene from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.
	GO Biological Process Annotations 2023	biological processes involving TRBC1 gene from the curated GO Biological Process Annotations 2023 dataset.
	GO Cellular Component Annotations 2023	cellular components containing TRBC1 protein from the curated GO Cellular Component Annotations 2023 dataset.
	GTEx Tissue-Specific Aging Signatures	tissue samples with high or low expression of TRBC1 gene relative to other tissue samples from the GTEx Tissue-Specific Aging Signatures dataset.
	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	cell lines with high or low expression of TRBC1 gene relative to other cell lines from the Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles dataset.
	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of TRBC1 gene from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	Pathway Commons Protein-Protein Interactions	interacting proteins for TRBC1 from the Pathway Commons Protein-Protein Interactions dataset.
	Reactome Pathways	pathways involving TRBC1 protein from the Reactome Pathways dataset.
	TISSUES Experimental Tissue Protein Expression Evidence Scores	tissues with high expression of TRBC1 protein in proteomics datasets from the TISSUES Experimental Tissue Protein Expression Evidence Scores dataset.
	TISSUES Text-mining Tissue Protein Expression Evidence Scores	tissues co-occuring with TRBC1 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.