TRIM29 Gene

HGNC Family	Tripartite motif-containing (TRIM)
Name	tripartite motif containing 29
Description	The protein encoded by this gene belongs to the TRIM protein family. It has multiple zinc finger motifs and a leucine zipper motif. It has been proposed to form homo- or heterodimers which are involved in nucleic acid binding. Thus, it may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. It may also function in the suppression of radiosensitivity since it is associated with ataxia telangiectasia phenotype. [provided by RefSeq, Jul 2008]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nTRIM29, also known as ATDC, is a multifunctional tripartite motif protein whose expression and activity are highly context‐dependent. In pancreatic cancer, TRIM29 is overexpressed and promotes cell proliferation and tumor growth by stabilizing β‐catenin signaling through effects on Disheveled-2, while in diagnostic immunohistochemical panels its differential expression helps distinguish malignant from benign epithelial cells in lung and prostate tissues."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "3"}]}, {"type": "t", "text": ""}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nIn several tumor types, TRIM29 modulates growth-controlling pathways through interactions with key transcription factors. In cell culture models, TRIM29 drives rapid proliferation and confers resistance to ionizing radiation by binding to and sequestering p53 away from the nucleus, thereby inhibiting p53-dependent gene activation; accordingly, TRIM29 associates with and is regulated by enzymes such as HDAC9 and Tip60 that control p53 acetylation. In parallel, elevated TRIM29 expression in colorectal and bladder cancers correlates with increased invasion, metastasis, and poor patient prognosis, whereas in some breast cancers TRIM29 is silenced by hypermethylation—its loss being linked to enhanced TWIST1 expression and epithelial–mesenchymal transition."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "4", "end_ref": "10"}]}, {"type": "t", "text": ""}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nBeyond its roles in cell proliferation and survival, TRIM29 functions as a chromatin-associated scaffold that facilitates the assembly of DNA repair proteins at sites of damage, thereby contributing to efficient DNA damage responses. In the setting of viral infection, such as with Epstein–Barr virus, TRIM29 is induced in airway epithelial cells to promote K48-linked ubiquitination and degradation of STING—a key adaptor in double-stranded DNA sensing—resulting in suppression of type I interferon production. In cutaneous squamous cell carcinoma, reduced TRIM29 levels are linked to altered keratin distribution and increased invasive behavior, and in nasopharyngeal cancer, overexpression of TRIM29 (often consequent to downregulation of specific regulatory miRNAs) is associated with activation of the PI3K/AKT pathway and enhanced metastatic potential."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "11", "end_ref": "14"}]}, {"type": "t", "text": ""}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nTRIM29 also contributes to the acquisition of cancer stem cell features and therapy resistance in several malignancies. In cervical cancer models, TRIM29 enhances migratory and invasive capabilities by modulating p63 signaling and the stability of β‐catenin, while in non–small cell lung cancer, aberrant upregulation of TRIM29 driven by long noncoding RNA–mediated sponging of miR‑134a‑5p underlies cisplatin resistance. In pancreatic ductal adenocarcinoma, TRIM29 regulates the stability of ISG15 via calpain‐mediated processing and thereby sustains cancer stem cell–like properties. Similarly, in ovarian cancer, translational upregulation of TRIM29 (facilitated by an m^6A-YTHDF1 mechanism) is linked to enhanced stemness and a poorer prognosis, and in papillary thyroid cancer TRIM29 promotes migration and invasion by modulating fibronectin 1 mRNA stability through a miRNA-regulated mechanism."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "15", "end_ref": "20"}]}, {"type": "t", "text": ""}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Lidong Wang, David G Heidt, Cheong J Lee, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Oncogenic function of ATDC in pancreatic cancer through Wnt pathway activation and beta-catenin stabilization."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Cell (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.ccr.2009.01.018"}], "href": "https://doi.org/10.1016/j.ccr.2009.01.018"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19249679"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19249679"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Brian Z Ring, Robert S Seitz, Rodney A Beck, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A novel five-antibody immunohistochemical test for subclassification of lung carcinoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mod Pathol (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/modpathol.2009.60"}], "href": "https://doi.org/10.1038/modpathol.2009.60"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19430419"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19430419"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Zhi-Yi Zhou, Guo-Yi Yang, Jing Zhou, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Significance of TRIM29 and β-catenin expression in non-small-cell lung cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Chin Med Assoc (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.jcma.2012.04.015"}], "href": "https://doi.org/10.1016/j.jcma.2012.04.015"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22721621"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22721621"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Zhigang Yuan, Alejandro Villagra, Lirong Peng, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The ATDC (TRIM29) protein binds p53 and antagonizes p53-mediated functions."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell Biol (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1128/MCB.01023-09"}], "href": "https://doi.org/10.1128/MCB.01023-09"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20368352"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20368352"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Zhigang Yuan, Lirong Peng, Rangasudhagar Radhakrishnan, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Histone deacetylase 9 (HDAC9) regulates the functions of the ATDC (TRIM29) protein."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M110.179333"}], "href": "https://doi.org/10.1074/jbc.M110.179333"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20947501"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20947501"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Takuya Sho, Tadasuke Tsukiyama, Tomonobu Sato, et al. "}, {"type": "b", "children": [{"type": "t", "text": "TRIM29 negatively regulates p53 via inhibition of Tip60."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochim Biophys Acta (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.bbamcr.2011.03.018"}], "href": "https://doi.org/10.1016/j.bbamcr.2011.03.018"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21463657"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21463657"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Niels Fristrup, Karin Birkenkamp-Demtröder, Thomas Reinert, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Multicenter validation of cyclin D1, MCM7, TRIM29, and UBE2C as prognostic protein markers in non-muscle-invasive bladder cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Am J Pathol (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.ajpath.2012.10.017"}], "href": "https://doi.org/10.1016/j.ajpath.2012.10.017"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23201130"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23201130"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Tao Jiang, Hua-mei Tang, Su Lu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Up-regulation of tripartite motif-containing 29 promotes cancer cell proliferation and predicts poor survival in colorectal cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Med Oncol (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s12032-013-0715-4"}], "href": "https://doi.org/10.1007/s12032-013-0715-4"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24078150"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24078150"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Lingbao Ai, Wan-Ju Kim, Merve Alpay, et al. "}, {"type": "b", "children": [{"type": "t", "text": "TRIM29 suppresses TWIST1 and invasive breast cancer behavior."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Res (2014)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1158/0008-5472.CAN-13-3579"}], "href": "https://doi.org/10.1158/0008-5472.CAN-13-3579"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24950909"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24950909"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Weihong Xu, Bin Xu, Yiting Yao, et al. "}, {"type": "b", "children": [{"type": "t", "text": "RNA interference against TRIM29 inhibits migration and invasion of colorectal cancer cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Oncol Rep (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3892/or.2016.4941"}], "href": "https://doi.org/10.3892/or.2016.4941"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27430345"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27430345"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Yasushi Masuda, Hidehisa Takahashi, Shigeo Sato, et al. "}, {"type": "b", "children": [{"type": "t", "text": "TRIM29 regulates the assembly of DNA repair proteins into damaged chromatin."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Commun (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/ncomms8299"}], "href": "https://doi.org/10.1038/ncomms8299"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26095369"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26095369"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Junji Xing, Ao Zhang, Hua Zhang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "TRIM29 promotes DNA virus infections by inhibiting innate immune response."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Commun (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41467-017-00101-w"}], "href": "https://doi.org/10.1038/s41467-017-00101-w"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29038422"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29038422"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Yan Yang, Qing Li, Lili Guo "}, {"type": "b", "children": [{"type": "t", "text": "MicroRNA‑122 acts as tumor suppressor by targeting TRIM29 and blocking the activity of PI3K/AKT signaling in nasopharyngeal carcinoma in vitro."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Med Rep (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3892/mmr.2018.8894"}], "href": "https://doi.org/10.3892/mmr.2018.8894"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29693120"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29693120"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Teruki Yanagi, Masashi Watanabe, Hiroo Hata, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Loss of TRIM29 Alters Keratin Distribution to Promote Cell Invasion in Squamous Cell Carcinoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Res (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1158/0008-5472.CAN-18-1495"}], "href": "https://doi.org/10.1158/0008-5472.CAN-18-1495"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30389700"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30389700"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Yasushi Masuda, Hidehisa Takahashi, Shigetsugu Hatakeyama "}, {"type": "b", "children": [{"type": "t", "text": "TRIM29 regulates the p63-mediated pathway in cervical cancer cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochim Biophys Acta (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.bbamcr.2015.05.035"}], "href": "https://doi.org/10.1016/j.bbamcr.2015.05.035"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26071105"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26071105"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Rui Xu, Jingye Hu, Tiansong Zhang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "TRIM29 overexpression is associated with poor prognosis and promotes tumor progression by activating Wnt/β-catenin pathway in cervical cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Oncotarget (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.18632/oncotarget.8686"}], "href": "https://doi.org/10.18632/oncotarget.8686"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27081037"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27081037"}]}, {"type": "r", "ref": 17, "children": [{"type": "t", "text": "Jia Sun, Jing Yan, Huai-Yu Qiao, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Loss of TRIM29 suppresses cancer stem cell-like characteristics of PDACs via accelerating ISG15 degradation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Oncogene (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41388-019-0992-2"}], "href": "https://doi.org/10.1038/s41388-019-0992-2"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31501523"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31501523"}]}, {"type": "r", "ref": 18, "children": [{"type": "t", "text": "Shunxiang Luo, Ming Shen, Hui Chen, et al. 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"}, {"type": "b", "children": [{"type": "t", "text": "TRIM29 inhibits miR-873-5P biogenesis via CYTOR to upregulate fibronectin 1 and promotes invasion of papillary thyroid cancer cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Death Dis (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41419-020-03018-3"}], "href": "https://doi.org/10.1038/s41419-020-03018-3"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32994394"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32994394"}]}, {"type": "r", "ref": 20, "children": [{"type": "t", "text": "Liang Hao, Jia-Mei Wang, Bao-Qin Liu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "m6A-YTHDF1-mediated TRIM29 upregulation facilitates the stem cell-like phenotype of cisplatin-resistant ovarian cancer cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochim Biophys Acta Mol Cell Res (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.bbamcr.2020.118878"}], "href": "https://doi.org/10.1016/j.bbamcr.2020.118878"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33011193"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33011193"}]}]}]}
Synonyms	ATDC
Proteins	TRI29_HUMAN
NCBI Gene ID	23650
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

TRIM29 has 7,694 functional associations with biological entities spanning 9 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 115 datasets.

Click the + buttons to view associations for TRIM29 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

TRIM29 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of TRIM29 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of TRIM29 gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of TRIM29 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of TRIM29 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of TRIM29 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of TRIM29 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of TRIM29 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of TRIM29 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	small molecule perturbations changing expression of TRIM29 gene from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of TRIM29 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of TRIM29 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CCLE Cell Line Proteomics	Cell lines associated with TRIM29 protein from the CCLE Cell Line Proteomics dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with TRIM29 gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of TRIM29 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of TRIM29 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of TRIM29 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	CM4AI U2OS Cell Map Protein Localization Assemblies	assemblies containing TRIM29 protein from integrated AP-MS and IF data from the CM4AI U2OS Cell Map Protein Localization Assemblies dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of TRIM29 gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing TRIM29 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing TRIM29 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	cellular components containing TRIM29 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with TRIM29 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with TRIM29 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of TRIM29 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with TRIM29 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Disease Associations	diseases associated with TRIM29 gene/protein from the curated CTD Gene-Disease Associations dataset.
	DeepCoverMOA Drug Mechanisms of Action	small molecule perturbations with high or low expression of TRIM29 protein relative to other small molecule perturbations from the DeepCoverMOA Drug Mechanisms of Action dataset.
	DepMap CRISPR Gene Dependency	cell lines with fitness changed by TRIM29 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with TRIM29 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with TRIM29 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with TRIM29 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with TRIM29 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at TRIM29 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of TRIM29 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of TRIM29 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing TRIM29 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
	GAD Gene-Disease Associations	diseases associated with TRIM29 gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
	GAD High Level Gene-Disease Associations	diseases associated with TRIM29 gene in GWAS and other genetic association datasets from the GAD High Level Gene-Disease Associations dataset.
	GDSC Cell Line Gene Expression Profiles	cell lines with high or low expression of TRIM29 gene relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.
	GeneRIF Biological Term Annotations	biological terms co-occuring with TRIM29 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.