TRIM44 Gene

HGNC Family Zinc fingers, Tripartite motif-containing (TRIM)
Name tripartite motif containing 44
Description This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, namely a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. [provided by RefSeq, Jul 2008]
Summary
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nTRIM44 is a multifunctional regulator that exerts its biological actions through atypical deubiquitinating activities. It stabilizes key signaling proteins by preventing their ubiquitination and proteasomal degradation—for example, by binding to and stabilizing viral adaptor proteins (thereby enhancing antiviral type I interferon responses) and modulating proteins involved in DNA damage repair and autophagy. In vitro evidence shows that TRIM44 can promote oligomerization of substrates such as SQSTM1 (p62) and regulate deubiquitination events, ultimately modulating stress responses in cancer and other cells."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "4"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nIn the oncology arena, TRIM44 is widely reported as an oncogenic protein whose aberrant overexpression has been linked to enhanced tumor cell proliferation, migration, invasion, and resistance to apoptosis. Elevated TRIM44 levels have been observed in gastric, testicular, breast, lung, thyroid, hepatocellular, prostate, renal, cervical, ovarian, and other cancers, where its upregulation is frequently associated with aggressive clinicopathological features, epithelial‐to‐mesenchymal transition (EMT), activation of signaling cascades (such as NF‑κB, mTOR, MAPK, PI3K/Akt, and Wnt/β‑catenin), and ultimately, poor patient prognosis. In some cases, genetic alterations in TRIM44 (or its modulation by regulatory RNAs) even contribute to developmental disorders, highlighting its versatile influence on cell fate."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "5", "end_ref": "29"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nFurthermore, TRIM44 is intricately regulated by non‐coding RNAs—including microRNAs, long noncoding RNAs, and circular RNAs—which act as molecular sponges to modulate its expression, thereby influencing chemoresistance and the DNA damage response. For instance, in lung adenocarcinoma, TRIM44 stabilizes FLNA and increases BRCA1-dependent homologous recombination repair, contributing to cisplatin resistance. In myocardial infarction models, noncoding RNA–mediated upregulation of TRIM44 has been linked to the modulation of cardiomyocyte apoptosis under hypoxic stress. Collectively, these findings underscore the potential of TRIM44 both as a prognostic marker and as a therapeutic target across a spectrum of human diseases."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "30", "end_ref": "32"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Tomohiko Urano, Takahiko Usui, Shizu Takeda, et al. "}, {"type": "b", "children": [{"type": "t", "text": "TRIM44 interacts with and stabilizes terf, a TRIM ubiquitin E3 ligase."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem Biophys Res Commun (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.bbrc.2009.04.010"}], "href": "https://doi.org/10.1016/j.bbrc.2009.04.010"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19358823"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19358823"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Bo Yang, Jie Wang, Yanming Wang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Novel function of Trim44 promotes an antiviral response by stabilizing VISA."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Immunol (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.4049/jimmunol.1202507"}], "href": "https://doi.org/10.4049/jimmunol.1202507"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23460740"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23460740"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Lin Lyu, Tsung-Chin Lin, Nami McCarty "}, {"type": "b", "children": [{"type": "t", "text": "TRIM44 mediated p62 deubiquitination enhances DNA damage repair by increasing nuclear FLNA and 53BP1 expression."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Oncogene (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41388-021-01890-7"}], "href": "https://doi.org/10.1038/s41388-021-01890-7"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34211088"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34211088"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Yuqin Wang, Lin Lyu, Trung Vu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "TRIM44 enhances autophagy via SQSTM1 oligomerization in response to oxidative stress."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Sci Rep (2024)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41598-024-67832-x"}], "href": "https://doi.org/10.1038/s41598-024-67832-x"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "39152142"}], "href": "https://pubmed.ncbi.nlm.nih.gov/39152142"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Kingo Kashimoto, Shuhei Komatsu, Daisuke Ichikawa, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Overexpression of TRIM44 contributes to malignant outcome in gastric carcinoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Sci (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1111/j.1349-7006.2012.02407.x"}], "href": "https://doi.org/10.1111/j.1349-7006.2012.02407.x"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22862969"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22862969"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Xibo Zhang, Gang Qin, Guilan Chen, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Variants in TRIM44 Cause Aniridia by Impairing PAX6 Expression."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Hum Mutat (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/humu.22907"}], "href": "https://doi.org/10.1002/humu.22907"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26394807"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26394807"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Ying Xing, Qingwei Meng, Xuesong Chen, et al. "}, {"type": "b", "children": [{"type": "t", "text": "TRIM44 promotes proliferation and metastasis in non‑small cell lung cancer via mTOR signaling pathway."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Oncotarget (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.18632/oncotarget.8586"}], "href": "https://doi.org/10.18632/oncotarget.8586"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27058415"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27058415"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Xinghua Zhu, Yaxun Wu, Xiaobing Miao, et al. "}, {"type": "b", "children": [{"type": "t", "text": "High expression of TRIM44 is associated with enhanced cell proliferation, migration, invasion, and resistance to doxorubicin in hepatocellular carcinoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Tumour Biol (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s13277-016-5316-3"}], "href": "https://doi.org/10.1007/s13277-016-5316-3"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27619678"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27619678"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Yuta Yamada, Ken-Ichi Takayama, Tetsuya Fujimura, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A novel prognostic factor TRIM44 promotes cell proliferation and migration, and inhibits apoptosis in testicular germ cell tumor."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Sci (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1111/cas.13105"}], "href": "https://doi.org/10.1111/cas.13105"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27754579"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27754579"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Yuying Tan, Hanxin Yao, Jinghai Hu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Knockdown of TRIM44 Inhibits the Proliferation and Invasion in Prostate Cancer Cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Oncol Res (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3727/096504017X14854310794561"}], "href": "https://doi.org/10.3727/096504017X14854310794561"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28160462"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28160462"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Hidetaka Kawabata, Kotaro Azuma, Kazuhiro Ikeda, et al. "}, {"type": "b", "children": [{"type": "t", "text": "TRIM44 Is a Poor Prognostic Factor for Breast Cancer Patients as a Modulator of NF-κB Signaling."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Int J Mol Sci (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3390/ijms18091931"}], "href": "https://doi.org/10.3390/ijms18091931"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28885545"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28885545"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Zhenyu Zhou, Yang Liu, Mingde Ma, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Knockdown of TRIM44 inhibits the proliferation and invasion in papillary thyroid cancer cells through suppressing the Wnt/β-catenin signaling pathway."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biomed Pharmacother (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.biopha.2017.09.132"}], "href": "https://doi.org/10.1016/j.biopha.2017.09.132"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28965013"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28965013"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Rui Peng, Peng-Fei Zhang, Chi Zhang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Elevated TRIM44 promotes intrahepatic cholangiocarcinoma progression by inducing cell EMT via MAPK signaling."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Med (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/cam4.1313"}], "href": "https://doi.org/10.1002/cam4.1313"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29446253"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29446253"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Panpan Li, Hexuan Yin, Fanling Meng, et al. "}, {"type": "b", "children": [{"type": "t", "text": "High TRIM44 expression in endometrial carcinoma is associated with a poorer patient outcome."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Pathol Res Pract (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.prp.2018.03.007"}], "href": "https://doi.org/10.1016/j.prp.2018.03.007"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29526558"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29526558"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Zheng Chen, Tsung-Chin Lin, Xiaohong Bi, et al. "}, {"type": "b", "children": [{"type": "t", "text": "TRIM44 promotes quiescent multiple myeloma cell occupancy and survival in the osteoblastic niche via HIF-1α stabilization."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Leukemia (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41375-018-0222-x"}], "href": "https://doi.org/10.1038/s41375-018-0222-x"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30089913"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30089913"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Dian Xiong, Chun Jin, Xudong Ye, et al. "}, {"type": "b", "children": [{"type": "t", "text": "TRIM44 promotes human esophageal cancer progression via the AKT/mTOR pathway."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Sci (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1111/cas.13762"}], "href": "https://doi.org/10.1111/cas.13762"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30098109"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30098109"}]}, {"type": "r", "ref": 17, "children": [{"type": "t", "text": "Shuang Liu, Fanling Meng, Jing Ding, et al. "}, {"type": "b", "children": [{"type": "t", "text": "High TRIM44 expression as a valuable biomarker for diagnosis and prognosis in cervical cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biosci Rep (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1042/BSR20181639"}], "href": "https://doi.org/10.1042/BSR20181639"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30792262"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30792262"}]}, {"type": "r", "ref": 18, "children": [{"type": "t", "text": "Xia Zhou, Yadong Yang, Pengcheng Ma, et al. "}, {"type": "b", "children": [{"type": "t", "text": "TRIM44 is indispensable for glioma cell proliferation and cell cycle progression through AKT/p21/p27 signaling pathway."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Neurooncol (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s11060-019-03301-0"}], "href": "https://doi.org/10.1007/s11060-019-03301-0"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31605296"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31605296"}]}, {"type": "r", "ref": 19, "children": [{"type": "t", "text": "Peng Zou, Menghai Zhu, Chong Lian, et al. "}, {"type": "b", "children": [{"type": "t", "text": "miR-192-5p suppresses the progression of lung cancer bone metastasis by targeting TRIM44."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Sci Rep (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41598-019-56018-5"}], "href": "https://doi.org/10.1038/s41598-019-56018-5"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31873114"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31873114"}]}, {"type": "r", "ref": 20, "children": [{"type": "t", "text": "Yuta Yamada, Naoki Kimura, Ken-Ichi Takayama, et al. "}, {"type": "b", "children": [{"type": "t", "text": "TRIM44 promotes cell proliferation and migration by inhibiting FRK in renal cell carcinoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Sci (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1111/cas.14295"}], "href": "https://doi.org/10.1111/cas.14295"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31883420"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31883420"}]}, {"type": "r", "ref": 21, "children": [{"type": "t", "text": "X Ji, R Tao, L-Y Sun, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Down-regulation of long non-coding RNA DUXAP8 suppresses proliferation, metastasis and EMT by modulating miR-498 through TRIM44-mediated AKT/mTOR pathway in non-small-cell lung cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Eur Rev Med Pharmacol Sci (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.26355/eurrev_202003_20682"}], "href": "https://doi.org/10.26355/eurrev_202003_20682"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32271433"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32271433"}]}, {"type": "r", "ref": 22, "children": [{"type": "t", "text": "Guoliang Xiao, Qiuxi Yang, Ziwei Bao, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Expression of tripartite motif-containing 44 and its prognostic and clinicopathological value in human malignancies:a meta-analysis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "BMC Cancer (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/s12885-020-07014-w"}], "href": "https://doi.org/10.1186/s12885-020-07014-w"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32503466"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32503466"}]}, {"type": "r", "ref": 23, "children": [{"type": "t", "text": "Tianlei Kou, Deqian Sha, Fei Wang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The Novel Target of Colorectal Carcinoma: TRIM44 Regulates Cell Migration and Invasion via Activation of CXCR4/NF-κB Signaling."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Biochem Biophys (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s12013-020-00955-w"}], "href": "https://doi.org/10.1007/s12013-020-00955-w"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33151473"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33151473"}]}, {"type": "r", "ref": 24, "children": [{"type": "t", "text": "Pengbo Li, Gang Huang "}, {"type": "b", "children": [{"type": "t", "text": "Long noncoding RNA LINC00858 promotes the progression of ovarian cancer via regulating the miR-134-5p/TRIM44 axis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Recept Signal Transduct Res (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1080/10799893.2021.1968433"}], "href": "https://doi.org/10.1080/10799893.2021.1968433"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34423728"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34423728"}]}, {"type": "r", "ref": 25, "children": [{"type": "t", "text": "Xia Wang, Jian Lv, Bin He, et al. "}, {"type": "b", "children": [{"type": "t", "text": "CircFBXW8 Acts an Oncogenic Role in the Malignant Progression of Non-small Cell Lung Carcinoma by miR-370-3p-Dependent Regulation of TRIM44."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem Genet (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s10528-021-10177-1"}], "href": "https://doi.org/10.1007/s10528-021-10177-1"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34988777"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34988777"}]}, {"type": "r", "ref": 26, "children": [{"type": "t", "text": "Ladan Goshayeshi, Jalil Afshar, Hassan Mehrad-Majd "}, {"type": "b", "children": [{"type": "t", "text": "Clinical Significance of TRIM44 Expression in Patients with Gastric Cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Asian Pac J Cancer Prev (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.31557/APJCP.2022.23.5.1725"}], "href": "https://doi.org/10.31557/APJCP.2022.23.5.1725"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "35633558"}], "href": "https://pubmed.ncbi.nlm.nih.gov/35633558"}]}, {"type": "r", "ref": 27, "children": [{"type": "t", "text": "Xin Zhang, Xiusheng Wu, Ying Sun, et al. "}, {"type": "b", "children": [{"type": "t", "text": "TRIM44 regulates tumor immunity in gastric cancer through LOXL2-dependent extracellular matrix remodeling."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Oncol (Dordr) (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s13402-022-00759-5"}], "href": "https://doi.org/10.1007/s13402-022-00759-5"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "36512309"}], "href": "https://pubmed.ncbi.nlm.nih.gov/36512309"}]}, {"type": "r", "ref": 28, "children": [{"type": "t", "text": "Songlin Zhou, Cheng Wu, Qingsheng Tang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Silencing LINC00491 inhibits prostate cancer development through the miR-384/TRIM44 axis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biochem Mol Toxicol (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/jbt.23370"}], "href": "https://doi.org/10.1002/jbt.23370"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "37070216"}], "href": "https://pubmed.ncbi.nlm.nih.gov/37070216"}]}, {"type": "r", "ref": 29, "children": [{"type": "t", "text": "Yang Yu, ShiYing Li, Jialin Sun, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Overexpression of TRIM44 mediates the NF-κB pathway to promote the progression of ovarian cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Genes Genomics (2024)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s13258-024-01517-7"}], "href": "https://doi.org/10.1007/s13258-024-01517-7"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "38691326"}], "href": "https://pubmed.ncbi.nlm.nih.gov/38691326"}]}, {"type": "r", "ref": 30, "children": [{"type": "t", "text": "Fang Luo, Yitian Wu, Liying Zhu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Knockdown of HIF1A-AS2 suppresses TRIM44 to protect cardiomyocytes against hypoxia-induced injury."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Biol Int (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/cbin.11348"}], "href": "https://doi.org/10.1002/cbin.11348"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32222118"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32222118"}]}, {"type": "r", "ref": 31, "children": [{"type": "t", "text": "H-L Li, Y-A Duan, N Zhao "}, {"type": "b", "children": [{"type": "t", "text": "MiR-34a-5p directly targeting TRIM44 affects the biological behavior of ovarian cancer cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Eur Rev Med Pharmacol Sci (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.26355/eurrev_202102_24829"}], "href": "https://doi.org/10.26355/eurrev_202102_24829"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33629295"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33629295"}]}, {"type": "r", "ref": 32, "children": [{"type": "t", "text": "Shuai Zhang, Mengru Cao, Shi Yan, et al. "}, {"type": "b", "children": [{"type": "t", "text": "TRIM44 promotes BRCA1 functions in HR repair to induce Cisplatin Chemoresistance in Lung Adenocarcinoma by Deubiquitinating FLNA."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Int J Biol Sci (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.7150/ijbs.71283"}], "href": "https://doi.org/10.7150/ijbs.71283"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "35541909"}], "href": "https://pubmed.ncbi.nlm.nih.gov/35541909"}]}]}]}
Synonyms AN3, DIPB, MC7, HSA249128
Proteins TRI44_HUMAN
NCBI Gene ID 54765
API
Download Associations
Predicted Functions View TRIM44's ARCHS4 Predicted Functions.
Co-expressed Genes View TRIM44's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View TRIM44's ARCHS4 Predicted Functions.

Functional Associations

TRIM44 has 7,490 functional associations with biological entities spanning 8 categories (molecular profile, organism, chemical, disease, phenotype or trait, functional term, phrase or reference, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 112 datasets.

Click the + buttons to view associations for TRIM44 from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles tissues with high or low expression of TRIM44 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles tissues with high or low expression of TRIM44 gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles tissue samples with high or low expression of TRIM44 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray tissue samples with high or low expression of TRIM44 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq tissue samples with high or low expression of TRIM44 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles tissues with high or low expression of TRIM44 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
BioGPS Cell Line Gene Expression Profiles cell lines with high or low expression of TRIM44 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
BioGPS Human Cell Type and Tissue Gene Expression Profiles cell types and tissues with high or low expression of TRIM44 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
BioGPS Mouse Cell Type and Tissue Gene Expression Profiles cell types and tissues with high or low expression of TRIM44 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
Carcinogenome Chemical Perturbation Carcinogenicity Signatures small molecule perturbations changing expression of TRIM44 gene from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
CCLE Cell Line Gene CNV Profiles cell lines with high or low copy number of TRIM44 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
CCLE Cell Line Gene Expression Profiles cell lines with high or low expression of TRIM44 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
CCLE Cell Line Proteomics Cell lines associated with TRIM44 protein from the CCLE Cell Line Proteomics dataset.
CellMarker Gene-Cell Type Associations cell types associated with TRIM44 gene from the CellMarker Gene-Cell Type Associations dataset.
ChEA Transcription Factor Binding Site Profiles transcription factor binding site profiles with transcription factor binding evidence at the promoter of TRIM44 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
ChEA Transcription Factor Targets transcription factors binding the promoter of TRIM44 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
ChEA Transcription Factor Targets 2022 transcription factors binding the promoter of TRIM44 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
ClinVar Gene-Phenotype Associations 2025 phenotypes associated with TRIM44 gene from the curated ClinVar Gene-Phenotype Associations 2025 dataset.
CMAP Signatures of Differentially Expressed Genes for Small Molecules small molecule perturbations changing expression of TRIM44 gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
COMPARTMENTS Curated Protein Localization Evidence Scores cellular components containing TRIM44 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
COMPARTMENTS Experimental Protein Localization Evidence Scores cellular components containing TRIM44 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores dataset.
COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 cellular components containing TRIM44 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 dataset.
COMPARTMENTS Text-mining Protein Localization Evidence Scores cellular components co-occuring with TRIM44 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 cellular components co-occuring with TRIM44 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
COSMIC Cell Line Gene CNV Profiles cell lines with high or low copy number of TRIM44 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
COSMIC Cell Line Gene Mutation Profiles cell lines with TRIM44 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
CTD Gene-Chemical Interactions chemicals interacting with TRIM44 gene/protein from the curated CTD Gene-Chemical Interactions dataset.
CTD Gene-Disease Associations diseases associated with TRIM44 gene/protein from the curated CTD Gene-Disease Associations dataset.
dbGAP Gene-Trait Associations traits associated with TRIM44 gene in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.
DeepCoverMOA Drug Mechanisms of Action small molecule perturbations with high or low expression of TRIM44 protein relative to other small molecule perturbations from the DeepCoverMOA Drug Mechanisms of Action dataset.
DepMap CRISPR Gene Dependency cell lines with fitness changed by TRIM44 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
DISEASES Text-mining Gene-Disease Association Evidence Scores diseases co-occuring with TRIM44 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 diseases co-occuring with TRIM44 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
DisGeNET Gene-Disease Associations diseases associated with TRIM44 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
DisGeNET Gene-Phenotype Associations phenotypes associated with TRIM44 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
ENCODE Histone Modification Site Profiles histone modification site profiles with high histone modification abundance at TRIM44 gene from the ENCODE Histone Modification Site Profiles dataset.
ENCODE Transcription Factor Binding Site Profiles transcription factor binding site profiles with transcription factor binding evidence at the promoter of TRIM44 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
ENCODE Transcription Factor Targets transcription factors binding the promoter of TRIM44 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
ESCAPE Omics Signatures of Genes and Proteins for Stem Cells PubMedIDs of publications reporting gene signatures containing TRIM44 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
GAD Gene-Disease Associations diseases associated with TRIM44 gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
GAD High Level Gene-Disease Associations diseases associated with TRIM44 gene in GWAS and other genetic association datasets from the GAD High Level Gene-Disease Associations dataset.
GDSC Cell Line Gene Expression Profiles cell lines with high or low expression of TRIM44 gene relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.
GeneRIF Biological Term Annotations biological terms co-occuring with TRIM44 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
GeneSigDB Published Gene Signatures PubMedIDs of publications reporting gene signatures containing TRIM44 from the GeneSigDB Published Gene Signatures dataset.
GEO Signatures of Differentially Expressed Genes for Diseases disease perturbations changing expression of TRIM44 gene from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.
GEO Signatures of Differentially Expressed Genes for Gene Perturbations gene perturbations changing expression of TRIM44 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
GEO Signatures of Differentially Expressed Genes for Kinase Perturbations kinase perturbations changing expression of TRIM44 gene from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.
GEO Signatures of Differentially Expressed Genes for Small Molecules small molecule perturbations changing expression of TRIM44 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset.
GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations transcription factor perturbations changing expression of TRIM44 gene from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.
GEO Signatures of Differentially Expressed Genes for Viral Infections virus perturbations changing expression of TRIM44 gene from the GEO Signatures of Differentially Expressed Genes for Viral Infections dataset.
GO Biological Process Annotations 2023 biological processes involving TRIM44 gene from the curated GO Biological Process Annotations 2023 dataset.
GO Biological Process Annotations 2025 biological processes involving TRIM44 gene from the curated GO Biological Process Annotations2025 dataset.
GO Cellular Component Annotations 2015 cellular components containing TRIM44 protein from the curated GO Cellular Component Annotations 2015 dataset.
GO Molecular Function Annotations 2015 molecular functions performed by TRIM44 gene from the curated GO Molecular Function Annotations 2015 dataset.
GO Molecular Function Annotations 2023 molecular functions performed by TRIM44 gene from the curated GO Molecular Function Annotations 2023 dataset.
GO Molecular Function Annotations 2025 molecular functions performed by TRIM44 gene from the curated GO Molecular Function Annotations 2025 dataset.
GTEx Tissue Gene Expression Profiles tissues with high or low expression of TRIM44 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset.
GTEx Tissue Gene Expression Profiles 2023 tissues with high or low expression of TRIM44 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles 2023 dataset.
GTEx Tissue Sample Gene Expression Profiles tissue samples with high or low expression of TRIM44 gene relative to other tissue samples from the GTEx Tissue Sample Gene Expression Profiles dataset.
GTEx Tissue-Specific Aging Signatures tissue samples with high or low expression of TRIM44 gene relative to other tissue samples from the GTEx Tissue-Specific Aging Signatures dataset.
GWAS Catalog SNP-Phenotype Associations phenotypes associated with TRIM44 gene in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations dataset.
GWAS Catalog SNP-Phenotype Associations 2025 phenotypes associated with TRIM44 gene in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.
GWASdb SNP-Disease Associations diseases associated with TRIM44 gene in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.
GWASdb SNP-Phenotype Associations phenotypes associated with TRIM44 gene in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.
Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles cell lines with high or low expression of TRIM44 gene relative to other cell lines from the Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles dataset.
HPA Cell Line Gene Expression Profiles cell lines with high or low expression of TRIM44 gene relative to other cell lines from the HPA Cell Line Gene Expression Profiles dataset.
HPA Tissue Gene Expression Profiles tissues with high or low expression of TRIM44 gene relative to other tissues from the HPA Tissue Gene Expression Profiles dataset.
HPA Tissue Protein Expression Profiles tissues with high or low expression of TRIM44 protein relative to other tissues from the HPA Tissue Protein Expression Profiles dataset.
HPA Tissue Sample Gene Expression Profiles tissue samples with high or low expression of TRIM44 gene relative to other tissue samples from the HPA Tissue Sample Gene Expression Profiles dataset.
Hub Proteins Protein-Protein Interactions interacting hub proteins for TRIM44 from the curated Hub Proteins Protein-Protein Interactions dataset.
HuGE Navigator Gene-Phenotype Associations phenotypes associated with TRIM44 gene by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.
InterPro Predicted Protein Domain Annotations protein domains predicted for TRIM44 protein from the InterPro Predicted Protein Domain Annotations dataset.
JASPAR Predicted Human Transcription Factor Targets 2025 transcription factors regulating expression of TRIM44 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset.
JASPAR Predicted Mouse Transcription Factor Targets 2025 transcription factors regulating expression of TRIM44 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Mouse Transcription Factor Targets 2025 dataset.
JASPAR Predicted Transcription Factor Targets transcription factors regulating expression of TRIM44 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.
Kinase Library Serine Threonine Kinome Atlas kinases that phosphorylate TRIM44 protein from the Kinase Library Serine Threonine Atlas dataset.
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles cell lines with high or low copy number of TRIM44 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles cell lines with high or low expression of TRIM44 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles dataset.
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles cell lines with TRIM44 gene mutations from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset.
LINCS L1000 CMAP Chemical Perturbation Consensus Signatures small molecule perturbations changing expression of TRIM44 gene from the LINCS L1000 CMAP Chemical Perturbations Consensus Signatures dataset.
LINCS L1000 CMAP CRISPR Knockout Consensus Signatures gene perturbations changing expression of TRIM44 gene from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules small molecule perturbations changing expression of TRIM44 gene from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
LOCATE Curated Protein Localization Annotations cellular components containing TRIM44 protein in low- or high-throughput protein localization assays from the LOCATE Curated Protein Localization Annotations dataset.
LOCATE Predicted Protein Localization Annotations cellular components predicted to contain TRIM44 protein from the LOCATE Predicted Protein Localization Annotations dataset.
MiRTarBase microRNA Targets microRNAs targeting TRIM44 gene in low- or high-throughput microRNA targeting studies from the MiRTarBase microRNA Targets dataset.
MotifMap Predicted Transcription Factor Targets transcription factors regulating expression of TRIM44 gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.
MSigDB Cancer Gene Co-expression Modules co-expressed genes for TRIM44 from the MSigDB Cancer Gene Co-expression Modules dataset.
NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles drug perturbations changing expression of TRIM44 gene from the NIBR DRUG-seq U2OS MoA Box dataset.
Pathway Commons Protein-Protein Interactions interacting proteins for TRIM44 from the Pathway Commons Protein-Protein Interactions dataset.
PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations gene perturbations changing expression of TRIM44 gene from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations gene perturbations changing expression of TRIM44 gene from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
PFOCR Pathway Figure Associations 2023 pathways involving TRIM44 protein from the PFOCR Pathway Figure Associations 2023 dataset.
PFOCR Pathway Figure Associations 2024 pathways involving TRIM44 protein from the Wikipathways PFOCR 2024 dataset.
Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures gene perturbations changing expression of TRIM44 gene from the Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures dataset.
Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures gene perturbations changing expression of TRIM44 gene from the Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures dataset.
Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures gene perturbations changing expression of TRIM44 gene from the Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures dataset.
Roadmap Epigenomics Cell and Tissue Gene Expression Profiles cell types and tissues with high or low expression of TRIM44 gene relative to other cell types and tissues from the Roadmap Epigenomics Cell and Tissue Gene Expression Profiles dataset.
Roadmap Epigenomics Histone Modification Site Profiles histone modification site profiles with high histone modification abundance at TRIM44 gene from the Roadmap Epigenomics Histone Modification Site Profiles dataset.
RummaGEO Drug Perturbation Signatures drug perturbations changing expression of TRIM44 gene from the RummaGEO Drug Perturbation Signatures dataset.
RummaGEO Gene Perturbation Signatures gene perturbations changing expression of TRIM44 gene from the RummaGEO Gene Perturbation Signatures dataset.
Sanger Dependency Map Cancer Cell Line Proteomics cell lines associated with TRIM44 protein from the Sanger Dependency Map Cancer Cell Line Proteomics dataset.
Sci-Plex Drug Perturbation Signatures drug perturbations changing expression of TRIM44 gene from the Sci-Plex Drug Perturbation Signatures dataset.
Tahoe Therapeutics Tahoe 100M Perturbation Atlas drug perturbations changing expression of TRIM44 gene from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
TargetScan Predicted Conserved microRNA Targets microRNAs regulating expression of TRIM44 gene predicted using conserved miRNA seed sequences from the TargetScan Predicted Conserved microRNA Targets dataset.
TargetScan Predicted Nonconserved microRNA Targets microRNAs regulating expression of TRIM44 gene predicted using nonconserved miRNA seed sequences from the TargetScan Predicted Nonconserved microRNA Targets dataset.
TCGA Signatures of Differentially Expressed Genes for Tumors tissue samples with high or low expression of TRIM44 gene relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.
TISSUES Curated Tissue Protein Expression Evidence Scores tissues with high expression of TRIM44 protein from the TISSUES Curated Tissue Protein Expression Evidence Scores dataset.
TISSUES Curated Tissue Protein Expression Evidence Scores 2025 tissues with high expression of TRIM44 protein from the TISSUES Curated Tissue Protein Expression Evidence Scores 2025 dataset.
TISSUES Experimental Tissue Protein Expression Evidence Scores tissues with high expression of TRIM44 protein in proteomics datasets from the TISSUES Experimental Tissue Protein Expression Evidence Scores dataset.
TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 tissues with high expression of TRIM44 protein in proteomics datasets from the TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 dataset.
TISSUES Text-mining Tissue Protein Expression Evidence Scores tissues co-occuring with TRIM44 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.
TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 tissues co-occuring with TRIM44 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 dataset.