| Name | tRNA methyltransferase 44 homolog (S. cerevisiae) |
| Description | The protein encoded by this gene is a putative tRNA methyltransferase found in the cytoplasm. Defects in this gene may be a cause of partial epilepsy with pericentral spikes (PEPS), but that has not been proven definitively. [provided by RefSeq, May 2012] |
| Summary |
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nWhile the original request was to summarize the function of TRMT44, none of the provided abstracts mention TRMT44. Instead, they collectively detail the roles of gasdermin family proteins – such as GSDMD, GSDMA, and especially the murine Gsdma3 – in mediating programmed cell death and in regulating epithelial differentiation. Several studies describe how the N‐terminal domains of these proteins, once cleaved by inflammatory caspases or related proteases, bind membrane lipids and assemble into large oligomeric pores that trigger pyroptosis, an inflammatory and lytic form of cell death that is important for immune defense. (See:."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "3"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nOther abstracts focus on the function of gasdermin proteins in skin biology and hair follicle dynamics. Mutations in Gsdma3, for example, have been linked to diverse hair and skin phenotypes in mice—including alopecia, hyperkeratosis, and abnormal progression of the hair growth cycle. These studies indicate that Gsdma3 is crucial for proper keratinocyte differentiation and the regulation of apoptotic pathways (such as those mediated via caspase-3 and TNF-α signaling), as well as for maintaining the integrity of the hair follicle niche. Collectively, these findings highlight that gasdermin dysfunction can lead to disrupted cell death and differentiation, with downstream effects on epidermal structure and function. (See:."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "4", "end_ref": "14"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nAdditional reports extend the role of gasdermin proteins beyond the skin by implicating them in the development and homeostasis of other tissues, such as the mammary glands, where altered expression affects ductal formation and local immune responses. Moreover, some studies provide evidence for the modulation of signaling pathways (for example, the Wnt/β-catenin cascade) in these tissues, underscoring the diverse physiological roles of the gasdermin family. Despite these varied insights into gasdermin function—spanning membrane pore formation, regulation of apoptosis, and tissue differentiation—not one of the reviewed studies offers any information regarding TRMT44. (See:."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "15", "end_ref": "18"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Jingjin Ding, Kun Wang, Wang Liu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Pore-forming activity and structural autoinhibition of the gasdermin family."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nature (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/nature18590"}], "href": "https://doi.org/10.1038/nature18590"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27281216"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27281216"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Jianbin Ruan, Shiyu Xia, Xing Liu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Cryo-EM structure of the gasdermin A3 membrane pore."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nature (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41586-018-0058-6"}], "href": "https://doi.org/10.1038/s41586-018-0058-6"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29695864"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29695864"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Stefania A Mari, Kristyna Pluhackova, Joka Pipercevic, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Gasdermin-A3 pore formation propagates along variable pathways."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Commun (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41467-022-30232-8"}], "href": "https://doi.org/10.1038/s41467-022-30232-8"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "35545613"}], "href": "https://pubmed.ncbi.nlm.nih.gov/35545613"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "F Runkel, A Marquardt, C Stoeger, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The dominant alopecia phenotypes Bareskin, Rex-denuded, and Reduced Coat 2 are caused by mutations in gasdermin 3."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Genomics (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.ygeno.2004.07.003"}], "href": "https://doi.org/10.1016/j.ygeno.2004.07.003"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15475261"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15475261"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Declan P Lunny, Erica Weed, Patrick M Nolan, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Mutations in gasdermin 3 cause aberrant differentiation of the hair follicle and sebaceous gland."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Invest Dermatol (2005)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1111/j.0022-202X.2005.23623.x"}], "href": "https://doi.org/10.1111/j.0022-202X.2005.23623.x"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15737203"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15737203"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Shigekazu Tanaka, Masaru Tamura, Aya Aoki, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A new Gsdma3 mutation affecting anagen phase of first hair cycle."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem Biophys Res Commun (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.bbrc.2007.05.209"}], "href": "https://doi.org/10.1016/j.bbrc.2007.05.209"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17572385"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17572385"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Mingxing Lei, Xiang Gao, Li Yang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Gsdma3 gene is needed for the induction of apoptosis-driven catagen during mouse hair follicle cycle."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Histochem Cell Biol (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s00418-011-0845-8"}], "href": "https://doi.org/10.1007/s00418-011-0845-8"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21805153"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21805153"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Yue Zhou, Xuan Jiang, Pengyu Gu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Gsdma3 mutation causes bulge stem cell depletion and alopecia mediated by skin inflammation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Am J Pathol (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.ajpath.2011.10.034"}], "href": "https://doi.org/10.1016/j.ajpath.2011.10.034"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22155111"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22155111"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Mingxing Lei, Xiufeng Bai, Tian Yang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Gsdma3 is a new factor needed for TNF-α-mediated apoptosis signal pathway in mouse skin keratinocytes."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Histochem Cell Biol (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s00418-012-0960-1"}], "href": "https://doi.org/10.1007/s00418-012-0960-1"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22585037"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22585037"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Mingxing Lei, Tian Yang, Xiangdong Lai, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Upregulation of interfollicular epidermal and hair infundibulum β-catenin expression in Gsdma3 mutant mice."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Acta Histochem (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.acthis.2012.04.002"}], "href": "https://doi.org/10.1016/j.acthis.2012.04.002"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22694914"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22694914"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Peiliang Shi, An Tang, Li Xian, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Loss of conserved Gsdma3 self-regulation causes autophagy and cell death."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem J (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1042/BJ20150204"}], "href": "https://doi.org/10.1042/BJ20150204"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25825937"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25825937"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Xiufeng Bai, Mingxing Lei, Jiazhong Shi, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Roles of GasderminA3 in Catagen-Telogen Transition During Hair Cycling."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Invest Dermatol (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/jid.2015.147"}], "href": "https://doi.org/10.1038/jid.2015.147"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25860385"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25860385"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Pei-Hsuan Lin, Hsien-Yi Lin, Cheng-Chin Kuo, et al. "}, {"type": "b", "children": [{"type": "t", "text": "N-terminal functional domain of Gasdermin A3 regulates mitochondrial homeostasis via mitochondrial targeting."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biomed Sci (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/s12929-015-0152-0"}], "href": "https://doi.org/10.1186/s12929-015-0152-0"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26100518"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26100518"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Sebastian Swirski, Carsten Röger, Aldona Pienkowska-Schelling, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A Novel C-Terminal Mutation in Gsdma3 (C+/H-) Leads to Alopecia and Corneal Inflammatory Response in Mice."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Invest Ophthalmol Vis Sci (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1167/iovs.17-22658"}], "href": "https://doi.org/10.1167/iovs.17-22658"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29372254"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29372254"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Jin Li, Yue Zhou, Tian Yang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Gsdma3 is required for hair follicle differentiation in mice."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem Biophys Res Commun (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.bbrc.2010.10.094"}], "href": "https://doi.org/10.1016/j.bbrc.2010.10.094"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20977888"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20977888"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Guy D Leschziner, Alison J Coffey, Toby Andrew, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Q8IYL2 is a candidate gene for the familial epilepsy syndrome of Partial Epilepsy with Pericentral Spikes (PEPS)."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Epilepsy Res (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.eplepsyres.2011.05.010"}], "href": "https://doi.org/10.1016/j.eplepsyres.2011.05.010"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21658913"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21658913"}]}, {"type": "r", "ref": 17, "children": [{"type": "t", "text": "Haiying Guo, Senlin Xu, Yingxin Liu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Gsdma3 is required for mammary gland development in mice."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Histochem Cell Biol (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s00418-017-1542-z"}], "href": "https://doi.org/10.1007/s00418-017-1542-z"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28168650"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28168650"}]}, {"type": "r", "ref": 18, "children": [{"type": "t", "text": "Shao-Ting Li, Wei-Jeng Suen, Cheng-Heng Kao, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Gasdermin A3-Mediated Cell Death Causes Niche Collapse and Precocious Activation of Hair Follicle Stem Cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Invest Dermatol (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.jid.2020.02.033"}], "href": "https://doi.org/10.1016/j.jid.2020.02.033"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32302611"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32302611"}]}]}]}
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| Synonyms | METTL19, TRM44, C4ORF23 |
| Proteins | TRM44_HUMAN |
| NCBI Gene ID | 152992 |
| API | |
| Download Associations | |
| Predicted Functions |
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| Co-expressed Genes |
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| Expression in Tissues and Cell Lines |
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TRMT44 has 4,316 functional associations with biological entities spanning 9 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 91 datasets.
Click the + buttons to view associations for TRMT44 from the datasets below.
If available, associations are ranked by standardized value
| Dataset | Summary | |
|---|---|---|
| Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles | tissues with high or low expression of TRMT44 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset. | |
| Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles | tissues with high or low expression of TRMT44 gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset. | |
| Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles | tissue samples with high or low expression of TRMT44 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset. | |
| Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray | tissue samples with high or low expression of TRMT44 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset. | |
| Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq | tissue samples with high or low expression of TRMT44 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset. | |
| Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles | tissues with high or low expression of TRMT44 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset. | |
| BioGPS Cell Line Gene Expression Profiles | cell lines with high or low expression of TRMT44 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset. | |
| BioGPS Human Cell Type and Tissue Gene Expression Profiles | cell types and tissues with high or low expression of TRMT44 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset. | |
| BioGPS Mouse Cell Type and Tissue Gene Expression Profiles | cell types and tissues with high or low expression of TRMT44 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset. | |
| CCLE Cell Line Gene CNV Profiles | cell lines with high or low copy number of TRMT44 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset. | |
| CCLE Cell Line Gene Expression Profiles | cell lines with high or low expression of TRMT44 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset. | |
| CellMarker Gene-Cell Type Associations | cell types associated with TRMT44 gene from the CellMarker Gene-Cell Type Associations dataset. | |
| ChEA Transcription Factor Binding Site Profiles | transcription factor binding site profiles with transcription factor binding evidence at the promoter of TRMT44 gene from the CHEA Transcription Factor Binding Site Profiles dataset. | |
| ChEA Transcription Factor Targets | transcription factors binding the promoter of TRMT44 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset. | |
| ChEA Transcription Factor Targets 2022 | transcription factors binding the promoter of TRMT44 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset. | |
| CM4AI KOLF21J CRISPRi Gene Perturbation Atlas | gene perturbations changing expression of TRMT44 gene from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas dataset. | |
| CMAP Signatures of Differentially Expressed Genes for Small Molecules | small molecule perturbations changing expression of TRMT44 gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset. | |
| COMPARTMENTS Curated Protein Localization Evidence Scores | cellular components containing TRMT44 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset. | |
| COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 | cellular components containing TRMT44 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 dataset. | |
| COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 | cellular components co-occuring with TRMT44 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset. | |
| COSMIC Cell Line Gene CNV Profiles | cell lines with high or low copy number of TRMT44 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset. | |
| COSMIC Cell Line Gene Mutation Profiles | cell lines with TRMT44 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset. | |
| CTD Gene-Chemical Interactions | chemicals interacting with TRMT44 gene/protein from the curated CTD Gene-Chemical Interactions dataset. | |
| CTD Gene-Disease Associations | diseases associated with TRMT44 gene/protein from the curated CTD Gene-Disease Associations dataset. | |
| dbGAP Gene-Trait Associations | traits associated with TRMT44 gene in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset. | |
| DeepCoverMOA Drug Mechanisms of Action | small molecule perturbations with high or low expression of TRMT44 protein relative to other small molecule perturbations from the DeepCoverMOA Drug Mechanisms of Action dataset. | |
| DepMap CRISPR Gene Dependency | cell lines with fitness changed by TRMT44 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset. | |
| DISEASES Experimental Gene-Disease Association Evidence Scores 2025 | diseases associated with TRMT44 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset. | |
| DISEASES Text-mining Gene-Disease Association Evidence Scores | diseases co-occuring with TRMT44 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset. | |
| DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 | diseases co-occuring with TRMT44 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset. | |
| DisGeNET Gene-Phenotype Associations | phenotypes associated with TRMT44 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset. | |
| ENCODE Histone Modification Site Profiles | histone modification site profiles with high histone modification abundance at TRMT44 gene from the ENCODE Histone Modification Site Profiles dataset. | |
| ENCODE Transcription Factor Binding Site Profiles | transcription factor binding site profiles with transcription factor binding evidence at the promoter of TRMT44 gene from the ENCODE Transcription Factor Binding Site Profiles dataset. | |
| ENCODE Transcription Factor Targets | transcription factors binding the promoter of TRMT44 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset. | |
| ESCAPE Omics Signatures of Genes and Proteins for Stem Cells | PubMedIDs of publications reporting gene signatures containing TRMT44 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset. | |
| GAD Gene-Disease Associations | diseases associated with TRMT44 gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset. | |
| GeneRIF Biological Term Annotations | biological terms co-occuring with TRMT44 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. | |
| GeneSigDB Published Gene Signatures | PubMedIDs of publications reporting gene signatures containing TRMT44 from the GeneSigDB Published Gene Signatures dataset. | |
| GEO Signatures of Differentially Expressed Genes for Diseases | disease perturbations changing expression of TRMT44 gene from the GEO Signatures of Differentially Expressed Genes for Diseases dataset. | |
| GEO Signatures of Differentially Expressed Genes for Kinase Perturbations | kinase perturbations changing expression of TRMT44 gene from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset. | |
| GEO Signatures of Differentially Expressed Genes for Small Molecules | small molecule perturbations changing expression of TRMT44 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset. | |
| GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations | transcription factor perturbations changing expression of TRMT44 gene from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset. | |
| GEO Signatures of Differentially Expressed Genes for Viral Infections | virus perturbations changing expression of TRMT44 gene from the GEO Signatures of Differentially Expressed Genes for Viral Infections dataset. | |
| GO Biological Process Annotations 2015 | biological processes involving TRMT44 gene from the curated GO Biological Process Annotations 2015 dataset. | |
| GO Biological Process Annotations 2023 | biological processes involving TRMT44 gene from the curated GO Biological Process Annotations 2023 dataset. | |
| GO Biological Process Annotations 2025 | biological processes involving TRMT44 gene from the curated GO Biological Process Annotations2025 dataset. | |
| GO Cellular Component Annotations 2015 | cellular components containing TRMT44 protein from the curated GO Cellular Component Annotations 2015 dataset. | |
| GO Molecular Function Annotations 2015 | molecular functions performed by TRMT44 gene from the curated GO Molecular Function Annotations 2015 dataset. | |
| GO Molecular Function Annotations 2023 | molecular functions performed by TRMT44 gene from the curated GO Molecular Function Annotations 2023 dataset. | |
| GO Molecular Function Annotations 2025 | molecular functions performed by TRMT44 gene from the curated GO Molecular Function Annotations 2025 dataset. | |
| GTEx eQTL 2025 | SNPs regulating expression of TRMT44 gene from the GTEx eQTL 2025 dataset. | |
| GTEx Tissue Gene Expression Profiles | tissues with high or low expression of TRMT44 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset. | |
| GTEx Tissue Gene Expression Profiles 2023 | tissues with high or low expression of TRMT44 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles 2023 dataset. | |
| GTEx Tissue Sample Gene Expression Profiles | tissue samples with high or low expression of TRMT44 gene relative to other tissue samples from the GTEx Tissue Sample Gene Expression Profiles dataset. | |
| GWAS Catalog SNP-Phenotype Associations | phenotypes associated with TRMT44 gene in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations dataset. | |
| GWAS Catalog SNP-Phenotype Associations 2025 | phenotypes associated with TRMT44 gene in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset. | |
| HMDB Metabolites of Enzymes | interacting metabolites for TRMT44 protein from the curated HMDB Metabolites of Enzymes dataset. | |
| HPA Cell Line Gene Expression Profiles | cell lines with high or low expression of TRMT44 gene relative to other cell lines from the HPA Cell Line Gene Expression Profiles dataset. | |
| HPA Tissue Gene Expression Profiles | tissues with high or low expression of TRMT44 gene relative to other tissues from the HPA Tissue Gene Expression Profiles dataset. | |
| HPA Tissue Protein Expression Profiles | tissues with high or low expression of TRMT44 protein relative to other tissues from the HPA Tissue Protein Expression Profiles dataset. | |
| HPA Tissue Sample Gene Expression Profiles | tissue samples with high or low expression of TRMT44 gene relative to other tissue samples from the HPA Tissue Sample Gene Expression Profiles dataset. | |
| Hub Proteins Protein-Protein Interactions | interacting hub proteins for TRMT44 from the curated Hub Proteins Protein-Protein Interactions dataset. | |
| InterPro Predicted Protein Domain Annotations | protein domains predicted for TRMT44 protein from the InterPro Predicted Protein Domain Annotations dataset. | |
| JASPAR Predicted Human Transcription Factor Targets 2025 | transcription factors regulating expression of TRMT44 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset. | |
| JASPAR Predicted Mouse Transcription Factor Targets 2025 | transcription factors regulating expression of TRMT44 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Mouse Transcription Factor Targets 2025 dataset. | |
| JASPAR Predicted Transcription Factor Targets | transcription factors regulating expression of TRMT44 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset. | |
| Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles | cell lines with high or low copy number of TRMT44 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset. | |
| Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles | cell lines with high or low expression of TRMT44 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles dataset. | |
| Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles | cell lines with TRMT44 gene mutations from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset. | |
| LINCS L1000 CMAP Chemical Perturbation Consensus Signatures | small molecule perturbations changing expression of TRMT44 gene from the LINCS L1000 CMAP Chemical Perturbations Consensus Signatures dataset. | |
| LOCATE Predicted Protein Localization Annotations | cellular components predicted to contain TRMT44 protein from the LOCATE Predicted Protein Localization Annotations dataset. | |
| MotifMap Predicted Transcription Factor Targets | transcription factors regulating expression of TRMT44 gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset. | |
| MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations | gene perturbations changing expression of TRMT44 gene from the MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations dataset. | |
| NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles | drug perturbations changing expression of TRMT44 gene from the NIBR DRUG-seq U2OS MoA Box dataset. | |
| NURSA Protein Complexes | protein complexs containing TRMT44 protein recovered by IP-MS from the NURSA Protein Complexes dataset. | |
| Pathway Commons Protein-Protein Interactions | interacting proteins for TRMT44 from the Pathway Commons Protein-Protein Interactions dataset. | |
| PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations | gene perturbations changing expression of TRMT44 gene from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset. | |
| PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations | gene perturbations changing expression of TRMT44 gene from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset. | |
| Reactome Pathways 2024 | pathways involving TRMT44 protein from the Reactome Pathways 2024 dataset. | |
| Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles | cell types and tissues with high or low DNA methylation of TRMT44 gene relative to other cell types and tissues from the Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles dataset. | |
| Roadmap Epigenomics Cell and Tissue Gene Expression Profiles | cell types and tissues with high or low expression of TRMT44 gene relative to other cell types and tissues from the Roadmap Epigenomics Cell and Tissue Gene Expression Profiles dataset. | |
| Roadmap Epigenomics Histone Modification Site Profiles | histone modification site profiles with high histone modification abundance at TRMT44 gene from the Roadmap Epigenomics Histone Modification Site Profiles dataset. | |
| Rummagene Transcription Factor Associations 2026 | transcription factors regulating expression of TRMT44 gene from the Rummagene Transcription Factor Associations 2026 dataset. | |
| RummaGEO Drug Perturbation Signatures | drug perturbations changing expression of TRMT44 gene from the RummaGEO Drug Perturbation Signatures dataset. | |
| RummaGEO Gene Perturbation Signatures | gene perturbations changing expression of TRMT44 gene from the RummaGEO Gene Perturbation Signatures dataset. | |
| TargetScan Predicted Conserved microRNA Targets | microRNAs regulating expression of TRMT44 gene predicted using conserved miRNA seed sequences from the TargetScan Predicted Conserved microRNA Targets dataset. | |
| TargetScan Predicted Nonconserved microRNA Targets | microRNAs regulating expression of TRMT44 gene predicted using nonconserved miRNA seed sequences from the TargetScan Predicted Nonconserved microRNA Targets dataset. | |
| TCGA Signatures of Differentially Expressed Genes for Tumors | tissue samples with high or low expression of TRMT44 gene relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset. | |
| TISSUES Curated Tissue Protein Expression Evidence Scores | tissues with high expression of TRMT44 protein from the TISSUES Curated Tissue Protein Expression Evidence Scores dataset. | |
| TISSUES Curated Tissue Protein Expression Evidence Scores 2025 | tissues with high expression of TRMT44 protein from the TISSUES Curated Tissue Protein Expression Evidence Scores 2025 dataset. | |
| TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 | tissues co-occuring with TRMT44 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 dataset. | |
