TSPY10 Gene

Name testis specific protein, Y-linked 10
Description Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in sex differentiation. Predicted to be located in chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Mar 2025]
Summary
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The highlighted research emphasizes diverse regulatory mechanisms—including proteolytic activity, translational control, and transcriptional regulation—in processes such as spermatogenesis, meiotic initiation, and immune modulation. However, none of these investigations provide insights into TSPY10’s potential role. Further targeted studies will be required to elucidate the biological functions and regulatory impact of TSPY10."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "43"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Daniel H Ebert, Jan Deussing, Christoph Peters, et al. 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Synonyms TSPY3, TSPY1
Proteins TSPYA_HUMAN
NCBI Gene ID 100289087
API
Download Associations
Predicted Functions View TSPY10's ARCHS4 Predicted Functions.
Co-expressed Genes View TSPY10's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View TSPY10's ARCHS4 Predicted Functions.

Functional Associations

TSPY10 has 891 functional associations with biological entities spanning 6 categories (functional term, phrase or reference, disease, phenotype or trait, chemical, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 22 datasets.

Click the + buttons to view associations for TSPY10 from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles tissue samples with high or low expression of TSPY10 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
COMPARTMENTS Curated Protein Localization Evidence Scores cellular components containing TSPY10 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
COMPARTMENTS Curated Protein Localization Evidence Scores 2025 cellular components containing TSPY10 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
COMPARTMENTS Text-mining Protein Localization Evidence Scores cellular components co-occuring with TSPY10 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 cellular components co-occuring with TSPY10 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
DISEASES Text-mining Gene-Disease Association Evidence Scores diseases co-occuring with TSPY10 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 diseases co-occuring with TSPY10 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
DisGeNET Gene-Disease Associations diseases associated with TSPY10 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
DisGeNET Gene-Phenotype Associations phenotypes associated with TSPY10 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
GeneSigDB Published Gene Signatures PubMedIDs of publications reporting gene signatures containing TSPY10 from the GeneSigDB Published Gene Signatures dataset.
GO Cellular Component Annotations 2025 cellular components containing TSPY10 protein from the curated GO Cellular Component Annotations 2025 dataset.
HPA Tissue Protein Expression Profiles tissues with high or low expression of TSPY10 protein relative to other tissues from the HPA Tissue Protein Expression Profiles dataset.
InterPro Predicted Protein Domain Annotations protein domains predicted for TSPY10 protein from the InterPro Predicted Protein Domain Annotations dataset.
JASPAR Predicted Human Transcription Factor Targets 2025 transcription factors regulating expression of TSPY10 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset.
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles cell lines with high or low copy number of TSPY10 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.
Rummagene Transcription Factor Associations 2026 transcription factors regulating expression of TSPY10 gene from the Rummagene Transcription Factor Associations 2026 dataset.
RummaGEO Drug Perturbation Signatures drug perturbations changing expression of TSPY10 gene from the RummaGEO Drug Perturbation Signatures dataset.
RummaGEO Gene Perturbation Signatures gene perturbations changing expression of TSPY10 gene from the RummaGEO Gene Perturbation Signatures dataset.
TISSUES Curated Tissue Protein Expression Evidence Scores tissues with high expression of TSPY10 protein from the TISSUES Curated Tissue Protein Expression Evidence Scores dataset.
TISSUES Curated Tissue Protein Expression Evidence Scores 2025 tissues with high expression of TSPY10 protein from the TISSUES Curated Tissue Protein Expression Evidence Scores 2025 dataset.
TISSUES Text-mining Tissue Protein Expression Evidence Scores tissues co-occuring with TSPY10 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.
TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 tissues co-occuring with TSPY10 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 dataset.