USP17L2 Gene

Name	ubiquitin specific peptidase 17-like family member 2
Description	DUB3 is a member of the ubiquitin processing protease (UBP) subfamily of deubiquitinating enzymes. See USP1 (MIM 603478) for background information.[supplied by OMIM, Mar 2008]
Synonyms	DUB-3, DUB3, USP17
Proteins	U17L2_HUMAN
NCBI Gene ID	377630
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Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

USP17L2 has 892 functional associations with biological entities spanning 6 categories (molecular profile, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 28 datasets.

Click the + buttons to view associations for USP17L2 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome

USP17L2 Gene

Functional Associations

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Funding

	Dataset	Summary
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of USP17L2 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CHEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of USP17L2 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	CHEA Transcription Factor Targets	transcription factors binding the promoter of USP17L2 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing USP17L2 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of USP17L2 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with USP17L2 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	DISEASES Text-mining Gene-Disease Assocation Evidence Scores	diseases co-occuring with USP17L2 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at USP17L2 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of USP17L2 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of USP17L2 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	GeneRIF Biological Term Annotations	biological terms co-occuring with USP17L2 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
	GeneSigDB Published Gene Signatures	PubMedIDs of publications reporting gene signatures containing USP17L2 from the GeneSigDB Published Gene Signatures dataset.
	GO Biological Process Annotations	biological processes involving USP17L2 gene from the curated GO Biological Process Annotations dataset.
	GO Cellular Component Annotations	cellular components containing USP17L2 protein from the curated GO Cellular Component Annotations dataset.
	GO Molecular Function Annotations	molecular functions performed by USP17L2 gene from the curated GO Molecular Function Annotations dataset.
	GTEx Tissue Gene Expression Profiles	tissues with high or low expression of USP17L2 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset.
	HPA Tissue Gene Expression Profiles	tissues with high or low expression of USP17L2 gene relative to other tissues from the HPA Tissue Gene Expression Profiles dataset.
	HPA Tissue Protein Expression Profiles	tissues with high or low expression of USP17L2 protein relative to other tissues from the HPA Tissue Protein Expression Profiles dataset.
	HuGE Navigator Gene-Phenotype Associations	phenotypes associated with USP17L2 gene by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.
	InterPro Predicted Protein Domain Annotations	protein domains predicted for USP17L2 protein from the InterPro Predicted Protein Domain Annotations dataset.
	JASPAR Predicted Transcription Factor Targets	transcription factors regulating expression of USP17L2 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.
	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	cell lines with high or low copy number of USP17L2 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.
	LOCATE Predicted Protein Localization Annotations	cellular components predicted to contain USP17L2 protein from the LOCATE Predicted Protein Localization Annotations dataset.
	NURSA Protein Complexes	protein complexs containing USP17L2 protein recovered by IP-MS from the NURSA Protein Complexes dataset.
	Pathway Commons Protein-Protein Interactions	interacting proteins for USP17L2 from the Pathway Commons Protein-Protein Interactions dataset.
	Roadmap Epigenomics Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at USP17L2 gene from the Roadmap Epigenomics Histone Modification Site Profiles dataset.
	TCGA Signatures of Differentially Expressed Genes for Tumors	tissue samples with high or low expression of USP17L2 gene relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.
	TISSUES Text-mining Tissue Protein Expression Evidence Scores	tissues co-occuring with USP17L2 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.