WDR26 Gene

HGNC Family	WD repeat domain containing (WDR)
Name	WD repeat domain 26
Description	This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nWDR26, a WD40 repeat protein, functions as a versatile scaffold that modulates multiple intracellular signaling pathways critical for cell survival, migration, and stress responses. Differential methylation of the WDR26 gene has been associated with depressive disorders and proposed as a peripheral blood biomarker."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": " In tumor and immune cells, WDR26 directly binds the Gβγ subunits to assemble signaling complexes that selectively promote GPCR-dependent activation of the phosphatidylinositol 3‑kinase (PI3K)/AKT pathway and phospholipase C‑β2 (PLCβ2), thereby driving processes such as breast tumor cell growth, invasion, and leukocyte chemotaxis."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "2", "end_ref": "4"}]}, {"type": "t", "text": " Moreover, WDR26 has been shown to act as a negative regulator in mitogen‑activated protein kinase (MAPK) signaling"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "5"}]}, {"type": "t", "text": "and to modulate the canonical Wnt pathway by affecting β‑catenin degradation."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "6"}]}, {"type": "t", "text": " In addition, by promoting Rac1 translocation in a mechanism reminiscent of coronin 1A activity"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "7"}]}, {"type": "t", "text": "and by regulating FPR1‐dependent activation of Rho GTPases"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "8"}]}, {"type": "t", "text": ", WDR26 plays a vital role in cytoskeletal organization and cellular motility. It also exerts cytoprotective effects in oxidative stress, where its upregulation attenuates H₂O₂-induced cell death."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "9"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nBeyond its regulatory role in signal transduction, WDR26 is integral to the formation of supramolecular E3 ubiquitin ligase assemblies. As a core component of the CTLH (C-terminal to LisH) complex, WDR26 facilitates substrate recruitment and subsequent ubiquitylation events that control metabolic enzymes."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "10"}]}, {"type": "t", "text": " Importantly, heterozygous de novo mutations and haploinsufficiency of WDR26 have been implicated in a spectrum of neurodevelopmental abnormalities—collectively described as Skraban-Deardorff syndrome—characterized by intellectual disability, developmental delay, seizures, and distinct craniofacial dysmorphism."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "12", "end_ref": "16"}]}, {"type": "t", "text": " Structural analyses suggest that these pathogenic variants impair WDR26’s ability to integrate into higher-order CTLH E3 assemblies, thereby disrupting complex formation and normal substrate ubiquitylation, which likely contributes to the clinical manifestations observed in affected individuals.\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "A Córdova-Palomera, M Fatjó-Vilas, C Gastó, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Genome-wide methylation study on depression: differential methylation and variable methylation in monozygotic twins."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Transl Psychiatry (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/tp.2015.49"}], "href": "https://doi.org/10.1038/tp.2015.49"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25918994"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25918994"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Zhizeng Sun, Xiaoyun Tang, Fang Lin, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The WD40 repeat protein WDR26 binds Gβγ and promotes Gβγ-dependent signal transduction and leukocyte migration."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M111.301382"}], "href": "https://doi.org/10.1074/jbc.M111.301382"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22065575"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22065575"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Zhizeng Sun, Alan V Smrcka, Songhai Chen "}, {"type": "b", "children": [{"type": "t", "text": "WDR26 functions as a scaffolding protein to promote Gβγ-mediated phospholipase C β2 (PLCβ2) activation in leukocytes."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M113.462564"}], "href": "https://doi.org/10.1074/jbc.M113.462564"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23625927"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23625927"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Yuanchao Ye, Xiaoyun Tang, Zhizeng Sun, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Upregulated WDR26 serves as a scaffold to coordinate PI3K/ AKT pathway-driven breast cancer cell growth, migration, and invasion."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Oncotarget (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.18632/oncotarget.7439"}], "href": "https://doi.org/10.18632/oncotarget.7439"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26895380"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26895380"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Ying Zhu, Yuequn Wang, Chunzhi Xia, et al. "}, {"type": "b", "children": [{"type": "t", "text": "WDR26: a novel Gbeta-like protein, suppresses MAPK signaling pathway."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cell Biochem (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/jcb.20175"}], "href": "https://doi.org/10.1002/jcb.20175"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15378603"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15378603"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Toshiyasu Goto, Junhei Matsuzawa, Shun-Ichiro Iemura, et al. "}, {"type": "b", "children": [{"type": "t", "text": "WDR26 is a new partner of Axin1 in the canonical Wnt signaling pathway."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "FEBS Lett (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/1873-3468.12180"}], "href": "https://doi.org/10.1002/1873-3468.12180"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27098453"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27098453"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Antonio Castro-Castro, Olivia Muriel, Miguel A Del Pozo, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Characterization of Novel Molecular Mechanisms Favoring Rac1 Membrane Translocation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PLoS One (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1371/journal.pone.0166715"}], "href": "https://doi.org/10.1371/journal.pone.0166715"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27835684"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27835684"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Mizuho Hasegawa, Charles A Parkos, Asma Nusrat "}, {"type": "b", "children": [{"type": "t", "text": "WD40 Repeat Protein 26 Negatively Regulates Formyl Peptide Receptor-1 Mediated Wound Healing in Intestinal Epithelial Cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Am J Pathol (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.ajpath.2020.06.005"}], "href": "https://doi.org/10.1016/j.ajpath.2020.06.005"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32958140"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32958140"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Jie Zhao, Ying Liu, Xing Wei, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A novel WD-40 repeat protein WDR26 suppresses H2O2-induced cell death in neural cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Neurosci Lett (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.neulet.2009.05.024"}], "href": "https://doi.org/10.1016/j.neulet.2009.05.024"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19446606"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19446606"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Dawafuti Sherpa, Jakub Chrustowicz, Shuai Qiao, et al. "}, {"type": "b", "children": [{"type": "t", "text": "GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.molcel.2021.03.025"}], "href": "https://doi.org/10.1016/j.molcel.2021.03.025"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33905682"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33905682"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Karthik V Gottemukkala, Jakub Chrustowicz, Dawafuti Sherpa, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Non-canonical substrate recognition by the human WDR26-CTLH E3 ligase regulates prodrug metabolism."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell (2024)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.molcel.2024.04.014"}], "href": "https://doi.org/10.1016/j.molcel.2024.04.014"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "38759627"}], "href": "https://pubmed.ncbi.nlm.nih.gov/38759627"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Cara M Skraban, Constance F Wells, Preetha Markose, et al. "}, {"type": "b", "children": [{"type": "t", "text": "WDR26 Haploinsufficiency Causes a Recognizable Syndrome of Intellectual Disability, Seizures, Abnormal Gait, and Distinctive Facial Features."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Am J Hum Genet (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.ajhg.2017.06.002"}], "href": "https://doi.org/10.1016/j.ajhg.2017.06.002"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28686853"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28686853"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Auriane Cospain, Elise Schaefer, Marie Faoucher, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Skraban-Deardorff syndrome: Six new cases of WDR26-related disease and expansion of the clinical phenotype."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Clin Genet (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1111/cge.13933"}], "href": "https://doi.org/10.1111/cge.13933"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33506510"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33506510"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Lisa Pavinato, Slavica Trajkova, Enrico Grosso, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Expanding the clinical phenotype of the ultra-rare Skraban-Deardorff syndrome: Two novel individuals with WDR26 loss-of-function variants and a literature review."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Am J Med Genet A (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/ajmg.a.62157"}], "href": "https://doi.org/10.1002/ajmg.a.62157"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33675273"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33675273"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Jiacheng Hu, Mingming Xu, Xiaobo Zhu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Two Novel Variants of "}, {"type": "a", "children": [{"type": "t", "text": "i"}], "href": "i"}, {"type": "t", "text": "WDR26"}, {"type": "a", "children": [{"type": "t", "text": "/i"}], "href": "/i"}, {"type": "t", "text": " in Chinese Patients with Intellectual Disability."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Genes (Basel) (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3390/genes13050813"}], "href": "https://doi.org/10.3390/genes13050813"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "35627197"}], "href": "https://pubmed.ncbi.nlm.nih.gov/35627197"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Annette Gross, Judith Müller, Jakub Chrustowicz, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Skraban-Deardorff intellectual disability syndrome-associated mutations in WDR26 impair CTLH E3 complex assembly."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "FEBS Lett (2024)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/1873-3468.14866"}], "href": "https://doi.org/10.1002/1873-3468.14866"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "38575527"}], "href": "https://pubmed.ncbi.nlm.nih.gov/38575527"}]}]}]}
Synonyms	CDW2, SKDEAS, GID7
Proteins	WDR26_HUMAN
NCBI Gene ID	80232
API
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Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

WDR26 has 7,288 functional associations with biological entities spanning 8 categories (molecular profile, organism, disease, phenotype or trait, functional term, phrase or reference, chemical, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 111 datasets.

Click the + buttons to view associations for WDR26 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

WDR26 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of WDR26 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of WDR26 gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of WDR26 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of WDR26 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of WDR26 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of WDR26 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of WDR26 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of WDR26 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of WDR26 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of WDR26 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CCLE Cell Line Proteomics	Cell lines associated with WDR26 protein from the CCLE Cell Line Proteomics dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with WDR26 gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of WDR26 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of WDR26 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of WDR26 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	ClinVar Gene-Phenotype Associations 2025	phenotypes associated with WDR26 gene from the curated ClinVar Gene-Phenotype Associations 2025 dataset.
	CM4AI U2OS Cell Map Protein Localization Assemblies	assemblies containing WDR26 protein from integrated AP-MS and IF data from the CM4AI U2OS Cell Map Protein Localization Assemblies dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of WDR26 gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing WDR26 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing WDR26 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores	cellular components containing WDR26 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with WDR26 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with WDR26 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of WDR26 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with WDR26 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Chemical Interactions	chemicals interacting with WDR26 gene/protein from the curated CTD Gene-Chemical Interactions dataset.
	CTD Gene-Disease Associations	diseases associated with WDR26 gene/protein from the curated CTD Gene-Disease Associations dataset.
	DeepCoverMOA Drug Mechanisms of Action	small molecule perturbations with high or low expression of WDR26 protein relative to other small molecule perturbations from the DeepCoverMOA Drug Mechanisms of Action dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with WDR26 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with WDR26 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with WDR26 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with WDR26 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at WDR26 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of WDR26 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of WDR26 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing WDR26 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
	GAD High Level Gene-Disease Associations	diseases associated with WDR26 gene in GWAS and other genetic association datasets from the GAD High Level Gene-Disease Associations dataset.
	GDSC Cell Line Gene Expression Profiles	cell lines with high or low expression of WDR26 gene relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.
	GeneRIF Biological Term Annotations	biological terms co-occuring with WDR26 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
	GeneSigDB Published Gene Signatures	PubMedIDs of publications reporting gene signatures containing WDR26 from the GeneSigDB Published Gene Signatures dataset.