{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nThe provided collection of studies (11733994, 12015298, 12243745, 12475645, 15777791, 15824114, 16024816, 17008882, 17023412, 17177854, 17616934, 18356808, 19530222, 19766719, 21084308, 22260998, 22623588, 23948589, 24280453, 25387007, 25957482, 30893599, 35963565, 36408877) collectively explores the complex roles of basement membrane proteins—especially the nidogen isoforms (nidogen‐1 and nidogen‐2) and various laminin chains—in the assembly, stabilization, and tissue‐specific functionality of basement membranes. These studies detail how interactions between nidogen and laminin underlie key developmental processes (e.g., lung and kidney maturation, neuronal network stabilization, wound repair) and describe the redundancy and compensatory dynamics between nidogen isoforms that ensure basement membrane integrity across many tissues."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "24"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nNotably, none of these abstracts provide any information regarding the gene ZCCHC24. Although the studies collectively enhance our understanding of basement membrane composition and function through detailed analyses of nidogen, laminin, and their interactors, there is no data or discussion on ZCCHC24 within this body of literature. Thus, based on these abstracts alone, no functional role—if any—can be ascribed to ZCCHC24 in the context of basement membrane biology or related cellular processes.\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "T Sasaki, W Göhring, K Mann, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Short arm region of laminin-5 gamma2 chain: structure, mechanism of processing and binding to heparin and proteins."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Mol Biol (2001)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1006/jmbi.2001.5176"}], "href": "https://doi.org/10.1006/jmbi.2001.5176"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "11733994"}], "href": "https://pubmed.ncbi.nlm.nih.gov/11733994"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Michael Willem, Nicolai Miosge, Willi Halfter, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Specific ablation of the nidogen-binding site in the laminin gamma1 chain interferes with kidney and lung development."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Development (2002)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1242/dev.129.11.2711"}], "href": "https://doi.org/10.1242/dev.129.11.2711"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12015298"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12015298"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Katriina Salmivirta, Jan F Talts, Magnus Olsson, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Binding of mouse nidogen-2 to basement membrane components and cells and its expression in embryonic and adult tissues suggest complementary functions of the two nidogens."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Exp Cell Res (2002)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1006/excr.2002.5611"}], "href": "https://doi.org/10.1006/excr.2002.5611"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12243745"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12243745"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Nicolai Miosge, Takako Sasaki, Rupert Timpl "}, {"type": "b", "children": [{"type": "t", "text": "Evidence of nidogen-2 compensation for nidogen-1 deficiency in transgenic mice."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Matrix Biol (2002)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/s0945-053x(02)00070-7"}], "href": "https://doi.org/10.1016/s0945-053x(02"}, {"type": "t", "text": "00070-7) PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12475645"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12475645"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Yamato Kikkawa, Yoichi Mochizuki, Jeffrey H Miner, et al. 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