HGNC Family | Zinc fingers |
Name | zinc finger protein 30 |
Description | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Mar 2025] |
Summary |
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nNAIP proteins serve as critical cytosolic sensors in the innate immune response by directly recognizing bacterial ligands derived from type III secretion systems—including needle proteins, rod proteins, and flagellin. Upon ligand binding, NAIP molecules oligomerize with NLRC4 to form inflammasome complexes that in turn activate caspase‐1, triggering pyroptotic cell death and the secretion of pro‐inflammatory mediators. This ligand recognition and inflammasome assembly occurs in a cell type–dependent manner, with distinct expression patterns observed in macrophages, dendritic cells, and epithelial cells that tailor local host defenses against diverse bacterial pathogens."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "7"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nIn addition to its immune surveillance functions, NAIP plays an important role in cellular homeostasis through the inhibition of apoptosis. Its transcription is intricately regulated by multiple promoters, including domesticated long terminal repeats and transcription factors such as PAX2, which ensure tissue‐specific expression in neuronal, renal, and intestinal compartments. Such regulation contributes to neuroprotective effects—by limiting caspase activation in response to toxic insults—and is implicated in developmental processes as well as in the clinical spectrum of diseases like spinal muscular atrophy."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "8", "end_ref": "13"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nEmerging evidence further suggests that perturbations in the gut microbiota may influence NAIP‐dependent inflammasome pathways, thereby impacting mucosal immune responses. Altered bacterial communities, such as the overgrowth of sulfate‐reducing Desulfovibrio in ulcerative colitis, might interface with these innate defense mechanisms, highlighting the broader relevance of NAIP in maintaining intestinal homeostasis."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "14"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Jieling Yang, Yue Zhao, Jianjin Shi, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Human NAIP and mouse NAIP1 recognize bacterial type III secretion needle protein for inflammasome activation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Proc Natl Acad Sci U S A (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1073/pnas.1306376110"}], "href": "https://doi.org/10.1073/pnas.1306376110"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23940371"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23940371"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Manira Rayamajhi, Daniel E Zak, Joseph Chavarria-Smith, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Cutting edge: Mouse NAIP1 detects the type III secretion system needle protein."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Immunol (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.4049/jimmunol.1301549"}], "href": "https://doi.org/10.4049/jimmunol.1301549"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24043898"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24043898"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Jeannette L Tenthorey, Eric M Kofoed, Matthew D Daugherty, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Molecular basis for specific recognition of bacterial ligands by NAIP/NLRC4 inflammasomes."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell (2014)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.molcel.2014.02.018"}], "href": "https://doi.org/10.1016/j.molcel.2014.02.018"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24657167"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24657167"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Isabella Rauch, Jeannette L Tenthorey, Randilea D Nichols, et al. "}, {"type": "b", "children": [{"type": "t", "text": "NAIP proteins are required for cytosolic detection of specific bacterial ligands in vivo."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Exp Med (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1084/jem.20151809"}], "href": "https://doi.org/10.1084/jem.20151809"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27045008"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27045008"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Yue Zhao, Jianjin Shi, Xuyan Shi, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Genetic functions of the NAIP family of inflammasome receptors for bacterial ligands in mice."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Exp Med (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1084/jem.20160006"}], "href": "https://doi.org/10.1084/jem.20160006"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27114610"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27114610"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Mikael E Sellin, Anna A Müller, Boas Felmy, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Epithelium-intrinsic NAIP/NLRC4 inflammasome drives infected enterocyte expulsion to restrict Salmonella replication in the intestinal mucosa."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Host Microbe (2014)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.chom.2014.07.001"}], "href": "https://doi.org/10.1016/j.chom.2014.07.001"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25121751"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25121751"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Marco A Ataide, Graziele Z Manin, Samuel S Oliveira, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Inflammasome activation and CCR2-mediated monocyte-derived dendritic cell recruitment restrict Legionella pneumophila infection."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Eur J Immunol (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/eji.202249985"}], "href": "https://doi.org/10.1002/eji.202249985"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "36427489"}], "href": "https://pubmed.ncbi.nlm.nih.gov/36427489"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Mark T Romanish, Wynne M Lock, Louie N van de Lagemaat, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Repeated recruitment of LTR retrotransposons as promoters by the anti-apoptotic locus NAIP during mammalian evolution."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PLoS Genet (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1371/journal.pgen.0030010"}], "href": "https://doi.org/10.1371/journal.pgen.0030010"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17222062"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17222062"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Johannes K X Maier, Sylvia Balabanian, Cynthia R Coffill, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Distribution of neuronal apoptosis inhibitory protein in human tissues."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Histochem Cytochem (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1369/jhc.6A7144.2007"}], "href": "https://doi.org/10.1369/jhc.6A7144.2007"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17510375"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17510375"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Sylvain Lesné, Cecilia Gabriel, Deirdre A Nelson, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Akt-dependent expression of NAIP-1 protects neurons against amyloid-{beta} toxicity."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2005)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M413495200"}], "href": "https://doi.org/10.1074/jbc.M413495200"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15797869"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15797869"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Alison Dziarmaga, Pierre-Alain Hueber, Diana Iglesias, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Neuronal apoptosis inhibitory protein is expressed in developing kidney and is regulated by PAX2."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Am J Physiol Renal Physiol (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1152/ajprenal.00004.2006"}], "href": "https://doi.org/10.1152/ajprenal.00004.2006"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16735463"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16735463"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Charles Thompson, Devin Gary, Mark Mattson, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Kainic acid-induced naip expression in the hippocampus is blocked in mice lacking TNF receptors."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Brain Res Mol Brain Res (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.molbrainres.2004.01.009"}], "href": "https://doi.org/10.1016/j.molbrainres.2004.01.009"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15046874"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15046874"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Jennifer Ingram-Crooks, Martin Holcik, Suzanna Drmanic, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Distinct expression of neuronal apoptosis inhibitory protein (NAIP) during murine development."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Neuroreport (2002)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1097/00001756-200203250-00007"}], "href": "https://doi.org/10.1097/00001756-200203250-00007"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "11930148"}], "href": "https://pubmed.ncbi.nlm.nih.gov/11930148"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Yaping An, Zihan Zhai, Xin Wang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Targeting Desulfovibrio vulgaris flagellin-induced NAIP/NLRC4 inflammasome activation in macrophages attenuates ulcerative colitis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Adv Res (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.jare.2023.08.008"}], "href": "https://doi.org/10.1016/j.jare.2023.08.008"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "37586642"}], "href": "https://pubmed.ncbi.nlm.nih.gov/37586642"}]}]}]}
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Synonyms | KOX28 |
Proteins | ZNF30_HUMAN |
NCBI Gene ID | 90075 |
API | |
Download Associations | |
Predicted Functions |
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Co-expressed Genes |
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Expression in Tissues and Cell Lines |
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ZNF30 has 2,792 functional associations with biological entities spanning 8 categories (molecular profile, organism, functional term, phrase or reference, disease, phenotype or trait, chemical, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 73 datasets.
Click the + buttons to view associations for ZNF30 from the datasets below.
If available, associations are ranked by standardized value
Dataset | Summary | |
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Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles | tissues with high or low expression of ZNF30 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset. | |
Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray | tissue samples with high or low expression of ZNF30 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset. | |
Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq | tissue samples with high or low expression of ZNF30 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset. | |
Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles | tissues with high or low expression of ZNF30 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset. | |
BioGPS Human Cell Type and Tissue Gene Expression Profiles | cell types and tissues with high or low expression of ZNF30 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset. | |
CCLE Cell Line Gene CNV Profiles | cell lines with high or low copy number of ZNF30 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset. | |
CCLE Cell Line Gene Expression Profiles | cell lines with high or low expression of ZNF30 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset. | |
ChEA Transcription Factor Binding Site Profiles | transcription factor binding site profiles with transcription factor binding evidence at the promoter of ZNF30 gene from the CHEA Transcription Factor Binding Site Profiles dataset. | |
ChEA Transcription Factor Targets | transcription factors binding the promoter of ZNF30 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset. | |
ChEA Transcription Factor Targets 2022 | transcription factors binding the promoter of ZNF30 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset. | |
COMPARTMENTS Curated Protein Localization Evidence Scores | cellular components containing ZNF30 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset. | |
COMPARTMENTS Experimental Protein Localization Evidence Scores | cellular components containing ZNF30 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores dataset. | |
COMPARTMENTS Text-mining Protein Localization Evidence Scores | cellular components co-occuring with ZNF30 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset. | |
COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 | cellular components co-occuring with ZNF30 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset. | |
COSMIC Cell Line Gene CNV Profiles | cell lines with high or low copy number of ZNF30 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset. | |
COSMIC Cell Line Gene Mutation Profiles | cell lines with ZNF30 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset. | |
DepMap CRISPR Gene Dependency | cell lines with fitness changed by ZNF30 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset. | |
DISEASES Text-mining Gene-Disease Association Evidence Scores | diseases co-occuring with ZNF30 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset. | |
DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 | diseases co-occuring with ZNF30 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset. | |
ENCODE Histone Modification Site Profiles | histone modification site profiles with high histone modification abundance at ZNF30 gene from the ENCODE Histone Modification Site Profiles dataset. | |
ENCODE Transcription Factor Binding Site Profiles | transcription factor binding site profiles with transcription factor binding evidence at the promoter of ZNF30 gene from the ENCODE Transcription Factor Binding Site Profiles dataset. | |
ENCODE Transcription Factor Targets | transcription factors binding the promoter of ZNF30 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset. | |
ESCAPE Omics Signatures of Genes and Proteins for Stem Cells | PubMedIDs of publications reporting gene signatures containing ZNF30 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset. | |
GeneSigDB Published Gene Signatures | PubMedIDs of publications reporting gene signatures containing ZNF30 from the GeneSigDB Published Gene Signatures dataset. | |
GEO Signatures of Differentially Expressed Genes for Gene Perturbations | gene perturbations changing expression of ZNF30 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset. | |
GEO Signatures of Differentially Expressed Genes for Small Molecules | small molecule perturbations changing expression of ZNF30 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset. | |
GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations | transcription factor perturbations changing expression of ZNF30 gene from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset. | |
GEO Signatures of Differentially Expressed Genes for Viral Infections | virus perturbations changing expression of ZNF30 gene from the GEO Signatures of Differentially Expressed Genes for Viral Infections dataset. | |
GO Biological Process Annotations 2015 | biological processes involving ZNF30 gene from the curated GO Biological Process Annotations 2015 dataset. | |
GO Biological Process Annotations 2025 | biological processes involving ZNF30 gene from the curated GO Biological Process Annotations2025 dataset. | |
GO Cellular Component Annotations 2015 | cellular components containing ZNF30 protein from the curated GO Cellular Component Annotations 2015 dataset. | |
GO Cellular Component Annotations 2025 | cellular components containing ZNF30 protein from the curated GO Cellular Component Annotations 2025 dataset. | |
GO Molecular Function Annotations 2015 | molecular functions performed by ZNF30 gene from the curated GO Molecular Function Annotations 2015 dataset. | |
GO Molecular Function Annotations 2023 | molecular functions performed by ZNF30 gene from the curated GO Molecular Function Annotations 2023 dataset. | |
GO Molecular Function Annotations 2025 | molecular functions performed by ZNF30 gene from the curated GO Molecular Function Annotations 2025 dataset. | |
GTEx Tissue Gene Expression Profiles | tissues with high or low expression of ZNF30 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset. | |
GTEx Tissue Gene Expression Profiles 2023 | tissues with high or low expression of ZNF30 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles 2023 dataset. | |
GTEx Tissue Sample Gene Expression Profiles | tissue samples with high or low expression of ZNF30 gene relative to other tissue samples from the GTEx Tissue Sample Gene Expression Profiles dataset. | |
GWASdb SNP-Disease Associations | diseases associated with ZNF30 gene in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset. | |
GWASdb SNP-Phenotype Associations | phenotypes associated with ZNF30 gene in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset. | |
Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles | cell lines with high or low expression of ZNF30 gene relative to other cell lines from the Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles dataset. | |
HPA Cell Line Gene Expression Profiles | cell lines with high or low expression of ZNF30 gene relative to other cell lines from the HPA Cell Line Gene Expression Profiles dataset. | |
HPA Tissue Gene Expression Profiles | tissues with high or low expression of ZNF30 gene relative to other tissues from the HPA Tissue Gene Expression Profiles dataset. | |
HPA Tissue Protein Expression Profiles | tissues with high or low expression of ZNF30 protein relative to other tissues from the HPA Tissue Protein Expression Profiles dataset. | |
HPA Tissue Sample Gene Expression Profiles | tissue samples with high or low expression of ZNF30 gene relative to other tissue samples from the HPA Tissue Sample Gene Expression Profiles dataset. | |
HPM Cell Type and Tissue Protein Expression Profiles | cell types and tissues with high or low expression of ZNF30 protein relative to other cell types and tissues from the HPM Cell Type and Tissue Protein Expression Profiles dataset. | |
InterPro Predicted Protein Domain Annotations | protein domains predicted for ZNF30 protein from the InterPro Predicted Protein Domain Annotations dataset. | |
JASPAR Predicted Transcription Factor Targets | transcription factors regulating expression of ZNF30 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset. | |
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles | cell lines with high or low copy number of ZNF30 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset. | |
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles | cell lines with high or low expression of ZNF30 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles dataset. | |
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles | cell lines with ZNF30 gene mutations from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset. | |
KnockTF Gene Expression Profiles with Transcription Factor Perturbations | transcription factor perturbations changing expression of ZNF30 gene from the KnockTF Gene Expression Profiles with Transcription Factor Perturbations dataset. | |
LOCATE Predicted Protein Localization Annotations | cellular components predicted to contain ZNF30 protein from the LOCATE Predicted Protein Localization Annotations dataset. | |
MiRTarBase microRNA Targets | microRNAs targeting ZNF30 gene in low- or high-throughput microRNA targeting studies from the MiRTarBase microRNA Targets dataset. | |
NURSA Protein Complexes | protein complexs containing ZNF30 protein recovered by IP-MS from the NURSA Protein Complexes dataset. | |
Pathway Commons Protein-Protein Interactions | interacting proteins for ZNF30 from the Pathway Commons Protein-Protein Interactions dataset. | |
PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations | gene perturbations changing expression of ZNF30 gene from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset. | |
PFOCR Pathway Figure Associations 2024 | pathways involving ZNF30 protein from the Wikipathways PFOCR 2024 dataset. | |
Reactome Pathways 2014 | pathways involving ZNF30 protein from the Reactome Pathways dataset. | |
Reactome Pathways 2024 | pathways involving ZNF30 protein from the Reactome Pathways 2024 dataset. | |
Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures | gene perturbations changing expression of ZNF30 gene from the Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures dataset. | |
Roadmap Epigenomics Cell and Tissue Gene Expression Profiles | cell types and tissues with high or low expression of ZNF30 gene relative to other cell types and tissues from the Roadmap Epigenomics Cell and Tissue Gene Expression Profiles dataset. | |
Roadmap Epigenomics Histone Modification Site Profiles | histone modification site profiles with high histone modification abundance at ZNF30 gene from the Roadmap Epigenomics Histone Modification Site Profiles dataset. | |
RummaGEO Drug Perturbation Signatures | drug perturbations changing expression of ZNF30 gene from the RummaGEO Drug Perturbation Signatures dataset. | |
RummaGEO Gene Perturbation Signatures | gene perturbations changing expression of ZNF30 gene from the RummaGEO Gene Perturbation Signatures dataset. | |
TargetScan Predicted Nonconserved microRNA Targets | microRNAs regulating expression of ZNF30 gene predicted using nonconserved miRNA seed sequences from the TargetScan Predicted Nonconserved microRNA Targets dataset. | |
TCGA Signatures of Differentially Expressed Genes for Tumors | tissue samples with high or low expression of ZNF30 gene relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset. | |
TISSUES Curated Tissue Protein Expression Evidence Scores | tissues with high expression of ZNF30 protein from the TISSUES Curated Tissue Protein Expression Evidence Scores dataset. | |
TISSUES Curated Tissue Protein Expression Evidence Scores 2025 | tissues with high expression of ZNF30 protein from the TISSUES Curated Tissue Protein Expression Evidence Scores 2025 dataset. | |
TISSUES Experimental Tissue Protein Expression Evidence Scores | tissues with high expression of ZNF30 protein in proteomics datasets from the TISSUES Experimental Tissue Protein Expression Evidence Scores dataset. | |
TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 | tissues with high expression of ZNF30 protein in proteomics datasets from the TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 dataset. | |
TISSUES Text-mining Tissue Protein Expression Evidence Scores | tissues co-occuring with ZNF30 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset. | |
TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 | tissues co-occuring with ZNF30 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 dataset. | |