Small molecules which mimic acute myeloid leukemia
Canned Analysis
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General Information
AccessionDCA00009460
TitleSmall molecules which mimic acute myeloid leukemia
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the acute myeloid leukemia gene expression signature in the Mononuclear Leukocyte cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1bac9e467bea600fb8236
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:112
Cell TypeMononuclear Leukocyte
DO IDDOID:9119
Disease Nameacute myeloid leukemia
Organismhuman
UMLS CUIC0023467
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM39873, GSM39874, GSM39875, GSM39876
Perturbed SamplesGSM39819, GSM39820, GSM39821, GSM39822, GSM39823, GSM39824, GSM39825, GSM39826, GSM39827, GSM39828, GSM39829, GSM39830, GSM39831, GSM39832, GSM39833, GSM39834, GSM39835, GSM39836, GSM39837, GSM39838, GSM39839, GSM39840, GSM39841, GSM39842, GSM39843, GSM39
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE2191
Gene Expression Omnibus
Acute myeloid leukemia response to chemotherapy
7
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