Small molecules which reverse Carcinoma in situ of large intestine
Canned Analysis
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General Information
AccessionDCA00009617
TitleSmall molecules which reverse Carcinoma in situ of large intestine
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the Carcinoma in situ of large intestine gene expression signature in the Colon cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c6e1e467bea600fb8824
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:190
Cell TypeColon
Disease NameCarcinoma in situ of large intestine
Organismhuman
UMLS CUIC0686087
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM95473, GSM95474, GSM95475, GSM95476, GSM95477, GSM95478, GSM95479, GSM95480
Perturbed SamplesGSM95496, GSM95497, GSM95498, GSM95499, GSM95500, GSM95501, GSM95502, GSM95503, GSM95504, GSM95505, GSM95506, GSM95507, GSM95508, GSM95509, GSM95510
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE4183
Gene Expression Omnibus
Inflammation, adenoma and cancer: objective classification of colon biopsy specimens with gene expression signature
21
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