Small molecules which reverse hypertension
Canned Analysis
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General Information
AccessionDCA00009677
TitleSmall molecules which reverse hypertension
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the hypertension gene expression signature in the CNS - Brain (MMHCC) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1b9a7e467bea600fb81a4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:209
Cell TypeCNS - Brain (MMHCC)
DO IDDOID:10763
Disease Namehypertension
Organismrat
UMLS CUIC0020538
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM60118, GSM60119
Perturbed SamplesGSM60122, GSM60123, GSM60124
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE2739
Gene Expression Omnibus
Angiotensin II type 1 receptor antagonist effect on brain microvessels of hypertensive animals
7
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