Small molecules which mimic Ventricular hypertrophy
Canned Analysis
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General Information
AccessionDCA00009864
TitleSmall molecules which mimic Ventricular hypertrophy
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the Ventricular hypertrophy gene expression signature in the Myocardial tissue cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1ca2ee467bea600fb89cc
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:313
Cell TypeMyocardial tissue
Disease NameVentricular hypertrophy
Organismmouse
UMLS CUIC0340279
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM105487, GSM105488, GSM105489
Perturbed SamplesGSM105483, GSM105484, GSM105485, GSM105486
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE4678
Gene Expression Omnibus
Alpha-tropomyosin mutant models of familial cardiac hypertrophy
7
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