Small molecules which mimic schizophrenia
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00010306
TitleSmall molecules which mimic schizophrenia
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the schizophrenia gene expression signature in the brain tissue (frontal cortex) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c158e467bea600fb857a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDdz:545
Cell Typebrain tissue (frontal cortex)
DO IDDOID:5419
Disease Nameschizophrenia
Organismhuman
UMLS CUIC0220702
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1521654, GSM1521655, GSM1521656, GSM1521657, GSM1521658, GSM1521659, GSM1521660, GSM1521661, GSM1521662, GSM1521664, GSM1521665, GSM1521666, GSM1521667, GSM1521668, GSM1521669, GSM1521670, GSM1521671, GSM1521672, GSM1521673, GSM1521674, GSM1521675, GSM
Perturbed SamplesGSM1521685, GSM1521686, GSM1521687, GSM1521688, GSM1521689, GSM1521690, GSM1521691, GSM1521692, GSM1521693, GSM1521694, GSM1521695, GSM1521696, GSM1521697, GSM1521698, GSM1521699, GSM1521700, GSM1521701, GSM1521702, GSM1521703, GSM1521704, GSM1521705, GSM
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE62191
Gene Expression Omnibus
Gene expression profiles of patients with schizophrenia, bipolar disorder and healthy controls
14
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.