Small molecules which reverse bipolar disorder
Canned Analysis
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General Information
AccessionDCA00010309
TitleSmall molecules which reverse bipolar disorder
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the bipolar disorder gene expression signature in the brain tissue (frontal cortex) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c153e467bea600fb8578
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDdz:546
Cell Typebrain tissue (frontal cortex)
DO IDDOID:3312
Disease Namebipolar disorder
Organismhuman
UMLS CUIC0236780
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1521654, GSM1521655, GSM1521656, GSM1521657, GSM1521658, GSM1521659, GSM1521660, GSM1521661, GSM1521662, GSM1521664, GSM1521665, GSM1521666, GSM1521667, GSM1521668, GSM1521669, GSM1521670, GSM1521671, GSM1521672, GSM1521673, GSM1521674, GSM1521675, GSM
Perturbed SamplesGSM1521625, GSM1521626, GSM1521627, GSM1521628, GSM1521629, GSM1521630, GSM1521631, GSM1521632, GSM1521633, GSM1521634, GSM1521635, GSM1521636, GSM1521637, GSM1521638, GSM1521639, GSM1521640, GSM1521641, GSM1521642, GSM1521643, GSM1521644, GSM1521645, GSM
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE62191
Gene Expression Omnibus
Gene expression profiles of patients with schizophrenia, bipolar disorder and healthy controls
14
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