Small molecules which reverse lupus erythematosus
Canned Analysis
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General Information
AccessionDCA00010641
TitleSmall molecules which reverse lupus erythematosus
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the lupus erythematosus gene expression signature in the Peripheral blood B cells (inactive lupus) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c66be467bea600fb87e8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:739
Cell TypePeripheral blood B cells (inactive lupus)
DO IDDOID:8857
Disease Namelupus erythematosus
Organismhuman
UMLS CUIC0409974
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM746743, GSM746744, GSM746745, GSM746746, GSM746747, GSM746748, GSM746750, GSM746751, GSM746752
Perturbed SamplesGSM746726, GSM746727, GSM746728, GSM746729, GSM746730, GSM746731, GSM746732, GSM746733, GSM746734, GSM746735, GSM746736, GSM746737, GSM746738, GSM746739, GSM746740, GSM746741, GSM746742
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE30153
Gene Expression Omnibus
Quiescent systemic lupus erythematosus: peripheral blood B cells
7
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