Small molecules which reverse asthma
Canned Analysis
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General Information
AccessionDCA00010665
TitleSmall molecules which reverse asthma
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the asthma gene expression signature in the Airway epithelial cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1b9e8e467bea600fb81c4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:753
Cell TypeAirway epithelial cells
DO IDDOID:2841
Disease Nameasthma
Organismhuman
UMLS CUIC0004096
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM469508, GSM469513, GSM469515, GSM469516, GSM469517, GSM469519, GSM469521
Perturbed SamplesGSM469509, GSM469510, GSM469511, GSM469512, GSM469514, GSM469518, GSM469520, GSM469522, GSM469523
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE18965
Gene Expression Omnibus
Asthmatic atopic epithelium
7
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