Small molecules which reverse rheumatoid arthritis
Canned Analysis
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General Information
AccessionDCA00010691
TitleSmall molecules which reverse rheumatoid arthritis
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the rheumatoid arthritis gene expression signature in the Synovial fluid macrophages cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1be79e467bea600fb840c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:779
Cell TypeSynovial fluid macrophages
DO IDDOID:7148
Disease Namerheumatoid arthritis
Organismhuman
UMLS CUIC0003873
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM265436, GSM265439, GSM265445
Perturbed SamplesGSM265020, GSM265036, GSM265361, GSM265363, GSM265366
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE10500
Gene Expression Omnibus
Rheumatoid arthritis: synovial macrophages
7
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