Small molecules which mimic schizophrenia
Canned Analysis
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General Information
AccessionDCA00010806
TitleSmall molecules which mimic schizophrenia
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the schizophrenia gene expression signature in the Superior temporal cortex - postmortem - Female cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c42fe467bea600fb86ca
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:854
Cell TypeSuperior temporal cortex - postmortem - Female
DO IDDOID:5419
Disease Nameschizophrenia
Organismhuman
UMLS CUIC0220702
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM545725, GSM545728, GSM545729, GSM545730, GSM545734, GSM545735, GSM545738, GSM545740, GSM545741
Perturbed SamplesGSM545744, GSM545746, GSM545747, GSM545750, GSM545754, GSM545758, GSM545762, GSM545763, GSM545765, GSM545766
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE21935
Gene Expression Omnibus
Schizophrenia: postmortem superior temporal cortex
14
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