Small molecules which reverse schizophrenia
Canned Analysis
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General Information
AccessionDCA00010809
TitleSmall molecules which reverse schizophrenia
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the schizophrenia gene expression signature in the Superior temporal cortex - postmortem - Male cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c42ae467bea600fb86c8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:855
Cell TypeSuperior temporal cortex - postmortem - Male
DO IDDOID:5419
Disease Nameschizophrenia
Organismhuman
UMLS CUIC0220702
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM545726, GSM545727, GSM545731, GSM545732, GSM545733, GSM545736, GSM545737, GSM545739, GSM545742, GSM545743
Perturbed SamplesGSM545745, GSM545748, GSM545749, GSM545751, GSM545752, GSM545753, GSM545755, GSM545756, GSM545757, GSM545759, GSM545760, GSM545761, GSM545764
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE21935
Gene Expression Omnibus
Schizophrenia: postmortem superior temporal cortex
14
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