Small molecules which reverse Alitretinoin treatment
Canned Analysis
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General Information
AccessionDCA00012233
TitleSmall molecules which reverse Alitretinoin treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Alitretinoin treatment in the liver b cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d107e467bea600fb8d0e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2673
Cell Typeliver b
Drug NameAlitretinoin
DrugBank IDDB00523
Organismrat
SMILES IDC/C(=C/C=C/C(=C/C(=O)O)/C)/C=C/C1=C(C)CCCC1(C)C
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM89873, GSM89875, GSM89878, GSM89881
Perturbed SamplesGSM89858, GSM89861, GSM89864, GSM89867
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE3952
Gene Expression Omnibus
Targretin, 9-cis retinoic acid, and 4-hydroxyphenylretinamide effect on various organs
63
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