Targretin, 9-cis retinoic acid, and 4-hydroxyphenylretinamide effect on various organs
Transcriptomics Dataset
FAIR Metrics
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General Information
AccessionGSE3952
TitleTargretin, 9-cis retinoic acid, and 4-hydroxyphenylretinamide effect on various organs
DescriptionAnalysis of normal livers, lungs, and mammary glands from Sprague Dawleys treated with targretin (TGR), 9-cis retinoic acid (9cRA), or 4-hydroxyphenylretinamide (4HPR). Results provide insight into the molecular basis of the varying chemopreventive anti-cancer effects of these agents.
Landing Pagehttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE3952
RepositoryGene Expression Omnibus
Tools used to analyze the dataset

Keyword
Dataset Accession

Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Canned Analyses generated with the dataset

Dataset Accession
Tool Name
Direction
Cell Type
Drug Name
Geneset

Small molecules which mimic Alitretinoin treatment
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse Alitretinoin treatment
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic Alitretinoin treatment
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse Alitretinoin treatment
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic Alitretinoin treatment
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse Alitretinoin treatment
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic Fenretinide treatment
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse Fenretinide treatment
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic Bexarotene treatment
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse Bexarotene treatment
The L1000 database was queried in order to identify small molecule perturbations which rev...
...
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