Small molecules which mimic Alitretinoin treatment
Canned Analysis
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General Information
AccessionDCA00012236
TitleSmall molecules which mimic Alitretinoin treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Alitretinoin treatment in the mammary gland cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1dfe9e467bea600fb93a0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2675
Cell Typemammary gland
Drug NameAlitretinoin
DrugBank IDDB00523
Organismrat
SMILES IDC/C(=C/C=C/C(=C/C(=O)O)/C)/C=C/C1=C(C)CCCC1(C)C
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM89874, GSM89877, GSM89880, GSM90169
Perturbed SamplesGSM89860, GSM89863, GSM89866, GSM89869
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE3952
Gene Expression Omnibus
Targretin, 9-cis retinoic acid, and 4-hydroxyphenylretinamide effect on various organs
63
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