Small molecules which mimic Fenretinide treatment
Canned Analysis
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General Information
AccessionDCA00012238
TitleSmall molecules which mimic Fenretinide treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Fenretinide treatment in the LIVER from Sprague Dawleys cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e876e467bea600fb9762
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3559
Cell TypeLIVER from Sprague Dawleys
Drug NameFenretinide
Organismrat
PubChem CID5288209
SMILES IDCC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)NC2=CC=C(C=C2)O)C)C
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM89873, GSM89875, GSM89878, GSM89881
Perturbed SamplesGSM89841, GSM89843, GSM89846, GSM89870
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE3952
Gene Expression Omnibus
Targretin, 9-cis retinoic acid, and 4-hydroxyphenylretinamide effect on various organs
63
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